Abstract: The disclosure provides for pathogenic biomarkers and serum extracellular vesicular biomarkers that are associated with vascular anomalies and malformation of endothelial cells, and uses thereof, including for diagnosis, prognosis and therapy.
Type:
Grant
Filed:
June 3, 2019
Date of Patent:
April 9, 2024
Assignee:
The Regents of the University of California
Inventors:
Wenbin Tan, John Stuart Nelson, Dongbao Chen
Abstract: Method and system for quantifying target nucleic acids using real-time amplification and internal calibration adjustment. The approach employs a single fixed data point in combination with a single adjustment calibrator amplified on the instrument that is to be calibrated for approximating a complete calibration curve.
Type:
Grant
Filed:
April 17, 2018
Date of Patent:
October 10, 2023
Assignee:
GEN-PROBE INCORPORATED
Inventors:
Sangeetha Vijaysri Nair, Xianqun Wang, Susan K. Yamagata