Abstract: A method of combating plant-pathogenic bacteria, comprising applying to the bacteria or to a bacteria habitat a bactericidally effective amount of a cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid derivative of the formula ##STR1## in which A represents straight-chain or branched alkylene with 1 to 6 carbon atoms or a >C.dbd.CH-- radical,R.sup.1 represents alkoxycarbonyl with 1 to 6 carbon atoms in the alkyl part, benzyloxycarbonyl, carboxyl, optionally substituted carbamoyl, cyano or dialkoxyphosphonyl or alkylsulphonyl with 1 to 4 carbon atoms in the alkyl part, andR.sup.2 represents hydrogen, alkoxycarbonyl with 1 to 6 carbon atoms in the alkyl part, benzyloxycarbonyl, optionally substituted carbamoyl, cyano, chlorine, acetyl, alkyl with 1 to 3 carbon atoms or phenyl, orR.sup.1 and R.sup.2, together with the carbon atom which they substitute, can also form a 2-oxo-tetrahydrofuryl ring,R.sup.3, R.sup.4, R.sup.5 and R.sup.

Abstract: The present invention relates to a new compounded composition with synergistic properties, to dosage units thereof, and to the use of the said compounded composition and dosage units.The composition contains as active ingredients the amidinopenicillanic acid mecillinam or a pharmaceutically acceptable, non-toxic salt or pro-drug thereof in combination with another antibiotic compound of the formula ##STR1## or a pharmaceutically acceptable, non-toxic salt or pro-drug thereof, optionally together with pharmaceutically acceptable, non-toxic carriers and/or auxiliary agents.The new composition is valuable in the human and veterinary practice for the treatment of patients suffering from infectious diseases.

Abstract: An agent for the therapy of hypertension, which comprises as an effective component at least one compound selected from the group consisting of 9-chloro-5-oxo-7-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridine, a salt thereof and hydrates thereof.

Abstract: Hypertension and thrombotic conditions in mammals are treated by administration of sulphite, bisulphite or cyclic sulphite ester of a monohydric or polyhydric alcohol.

Abstract: A rapidly absorbable liquid formulation of a dihydropyridine comprising, by weight, about 0.5 to 10 parts of a dihydropyridine of the formula ##STR1## in which R.sub.1 is C.sub.1 -C.sub.4 -alkyl, optionally substituted by C.sub.2 -C.sub.3 -alkoxy,R.sub.2 is C.sub.1 -C.sub.10 -alkyl, optionally substituted by C.sub.1 -C.sub.3 -alkoxy, trifluoromethyl or N-methyl-N-benzylamino,R.sub.3 is C.sub.1 -C.sub.4 -alkyl, cyano or hydroxymethyl, andX is 2- or 3-nitro, 2,3-dichloro or 2,3.dbd.N--O--N.dbd.,20 to 60 parts of a solubilizing agent and 80 to 40 parts of a diluent.

Abstract: A lyophilized pharmaceutical solid composition containing cyclophosphamide for reconstitution with water to provide a solution for oral or parenteral administration. This lyophilized cyclophosphamide solid composition demonstrates improved stability, solubility characteristics and enhanced appearance compared with currently available dry powder pre-mix compositions of cyclophosphamide. The lyophilized solid composition contains about 20 parts by weight of cyclophosphamide, about 11/4-2 parts by weight of water and from about 10-85 parts by weight of excipient which is comprised mainly of mannitol. Processes for making the composition are disclosed.

Abstract: A fungicidal composition containing a fungicidally effective amount of tolchlofos-methyl [O,O-dimethyl O-(2,6-dichloro-4-methylphenyl) phosphorothioate] as an active ingredient, attapulgite clay as a carrier and polypropylene glycol as a stabilizer, its formulation and its use as a fungicide.

Abstract: A storage-stable highly active muzolimine composition comprising by weight about(a) 100 parts of muzolimine(b) 40-500 parts of starch(c) 20-100 parts of cellulose(d) 0.2-5 parts of silica, and(e) 0.1-3 parts of stearic acid, Ca stearate, Mg stearate and/or talc.

Abstract: A therapeutic composition for reducing blood acetaldehyde level in a patient comprises methionine and a physiologically tolerable carrier. Additionally, potassium citrate and Vitamin B6 may be present in the composition.

Abstract: Method for the treatment of calcifying pancreatitis which comprises administering an effective amount of trimethadione or dimethadione to a patient suffering from calcifying pancreatitis, by which pancreatic stones are effectively dissolved out.

Abstract: A pharmaceutical composition containing a therapeutically effective amount of a pyridinylimidazole 4- or 5-substituted carboxylic acid and esters thereof is provided to treat cardiovascular ailment.

Abstract: A method of producing .alpha..sub.2 -adrenergic receptor agonist activity by contacting an .alpha..sub.2 -adrenergic receptor with an effective amount of a compound of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently selected from hydrogen or loweralkyl of 1 or 2 carbon atoms, or a pharmaceutically acceptable salt thereof.

Abstract: Peripherally selective dopamine antagonists are useful in the treatment of ocular hypertension when administered topically to the eye.

Abstract: This invention relates to a novel method for the treatment of malarial infections in warm-blooded animals using the antibiotics X-14868A, LL-C23024 beta, LL-C23024 iota, and combinations theory and to compositions containing these antibiotics.

Abstract: m-Amino-.alpha.-methylphenethylamine, when administered internally, induces water diuresis in patients having edema.

Abstract: A biocidal composition suitable for use as a stabilizer in polymer systems using 2-mercaptopyridene-1-oxide or a derivative combined with an organophosphorous compound and a benzotriazole wherein the organophosphorous compound and the benzotriazole act together to stabilize the mercaptopyridene against degradation and discoloration of the polymer system.

Abstract: The use of a compound having the general formula: ##STR1## wherein n is 0 or a small integer, normally from 1 to 3; R is an alkyl or alkenyl group containing from 4 to 18 carbon atoms; and X is oxygen, sulfur or amide ##STR2## with the further proviso that any one or more of the OH groups can be replaced by a polar zwitterionic group such as NH.sub.4 + SO.sub.3 -; for the treatment of cholesterol gallstones by infusion of the solvent around the gallstones to dissolve them.