Patents Examined by Jr. Rollins
  • Inhibition of diarrhea induced by Escherichia coli heat-stable enterotoxin
    Patent number: 4587265
    Abstract: Substantially nontoxic materials such as cysteamine constituting a source of sulfhydryl groups are useful in inhibiting diarrhea induced by Escherichia coli heat-stable enterotoxin. Such materials block ST-induced secretion prior to the formation of cyclic GMP without interference with normal basal activity or metabolism and may inactivate ST itself by breaking disulfide bridges.
    Type: Grant
    Filed: February 7, 1983
    Date of Patent: May 6, 1986
    Assignee: St. Louis University
    Inventor: Richard N. Greenberg