Patents Examined by Julie Tavares
  • Patent number: 8647577
    Abstract: The described embodiments may provide a method of fabricating a chemical detection device. The method may comprise forming a microwell above a CMOS device. The microwell may comprise a bottom surface and sidewalls. The method may further comprise applying a first chemical to be selectively attached to the bottom surface of the microwell, forming a metal oxide layer on the sidewalls of the microwell, and applying a second chemical to be selectively attached to the sidewalls of the microwell. The second chemical may lack an affinity to the first chemical.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: February 11, 2014
    Assignee: Life Technologies Corporation
    Inventors: Wolfgang Hinz, John Matthew Mauro, Shifeng Li, James Bustillo
  • Patent number: 8632736
    Abstract: This disclosure is directed to systems for separating a target analyte from a suspension. A suspension is added to a tube. A float is also added to the tube, and the tube, float, and suspension are centrifuged together, causing the constituent components of the suspension to separate into different layers along the axial length of the tube according to their specific gravities. The float has a specific gravity that positions the float at approximately the same level as a layer containing the target analyte, when the tube, float and sample are centrifuged. Prior to isolation, the material may be located between an outer surface of the float and an inner surface of the tube, or within a central bore that extends longitudinally through the float. The target analyte may then be drawn into a compartment within the float, thereby isolating the target analyte from the other suspension constituents.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: January 21, 2014
    Assignee: Rarecyte, Inc.
    Inventors: Paul Spatafore, Jackie Lynn Stilwell, Arturo Ramirez, Evan Castiglia
  • Patent number: 8628727
    Abstract: The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax).
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: January 14, 2014
    Assignee: Northwestern University
    Inventors: Richard P. Van Duyne, Xiaoyu Zhang, Jing Zhao, Alyson V. Whitney, Jeffrey W. Elam, George C. Schatz, Peter C. Stair, Shengli Zou, Matthew Young, Olga Lyandres
  • Patent number: 8623297
    Abstract: The present invention relates to a device, to a system, and to a method for the preparation and fractioned dispensing of samples of a fluid. The device of the invention comprises a body having formed therein guide means suitable for receiving a sample-taker member and for guiding it in translation through the device, and at least one preparation chamber enabling an aliquot of a fluid sample dispensed into the chamber by a said sample-taker member to be prepared in a stream of a suitable reagent. The guide means pass through the preparation chamber and communicate therewith to enable an aliquot of fluid to be dispensed into the chamber in a determined position of the sample-taker member in the guide means. The preparation chamber has an introduction orifice for introducing at least one reagent into the chamber for mixing the reagent with an aliquot, and at least one dispensing orifice for dispensing the mixture formed by said aliquot and said reagent to recovery and/or analysis means.
    Type: Grant
    Filed: July 29, 2008
    Date of Patent: January 7, 2014
    Assignee: Horiba ABX SAS
    Inventors: Roger Le Comte, Guilhem Couderc, Paul Moreno
  • Patent number: 8591809
    Abstract: A substrate transfer container comprises a housing including a plurality of substrate slots positioned within a gas chamber having an interior environment. Each substrate slot accommodates a substrate undergoing a substrate manufacturing process, the interior environment of the gas chamber being selectively sealed from an exterior environment. A detection unit at the housing is constructed and arranged to detect an environmental property of the interior environment of the gas chamber, and to generate a detection signal in response. A signal transmission module at the housing is configured to wirelessly transmit a detection signal received from the detection unit.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: November 26, 2013
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Byung-Koog Ra, Tae-Sik Yun, Kunhyung Lee, Hyunjoon Kim, Hyeogki Kim, KiDoo Kim
  • Patent number: 8540948
    Abstract: A lidded container having a tubular container which at the bottom has a container base, at the top a container opening and below the container opening a sealing region on the internal wall, a lid which comprises a lid base and a plug protruding from the inside of the lid base, and which may be inserted through the container opening into a sealing position in the sealing region, and locking means for releasably locking the lid to the container comprising at least one latching projection projecting radially outward at the top edge of the container, at least one flexible and elastic connecting link projecting from the bottom side of the lid base on which a latching edge is arranged at a distance from the lid base vertically below the connection of the connecting link to the lid base.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: September 24, 2013
    Assignee: Eppendorf AG
    Inventor: Juergen Loehn
  • Patent number: 8540936
    Abstract: An erosion sensor that can separately monitor erosion and corrosion of a substrate, such as a wind turbine blade or a turbine blade used in devices such as gas turbines, aircraft engines, microturbines, steam turbines, and the like is disclosed. The sensor can include a first element or “erosion part” that is made of a corrosion resistant material. The first element of the sensor has similar erosion properties to the substrate being monitored. The sensor can further include a second element or a “corrosion part” that is made of a material having similar erosion and corrosion properties to the substrate. The sensor can provide an erosion indicator based on the erosion of the first element and a corrosion indicator based on the erosion and corrosion of the second element.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: September 24, 2013
    Assignee: General Electric Company
    Inventors: Rebecca Evelyn Hefner, Paul Stephen DiMascio
  • Patent number: 8535945
    Abstract: A system and method for concentrating samples. The system can include a first container adapted to contain a sample. The first container can include a first portion and a second portion adapted to be removably coupled to the first portion. The system can further include a second container comprising the second portion and a third portion adapted to be removably coupled to the second portion. The method can include centrifuging the first container in a first orientation toward the second portion of the first container; retaining a concentrate of the sample in the second portion of the first container; and centrifuging the second container in a second orientation toward the third portion of the second container, such that the concentrate retained in the second portion is moved into the third portion of the second container, the second orientation being different from the first orientation.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: September 17, 2013
    Assignee: 3M Innovative Properties Company
    Inventor: Kurt J. Halverson
  • Patent number: 8518349
    Abstract: A filtration syringe having at least a first and second chamber separated by a fluid permeable membrane, which may be selectively permeable to solids of a certain size, allows aspirated particle-filled fluid to be filtered within the syringe. A centrifuge tube apparatus is also provided for centrifuging a sample collected in a syringe, the apparatus comprising: a syringe comprising at one end a narrowed outlet and means for connection to a needle and at the opposing end a partially inserted syringe plunger; and a syringe holder having an interior for accepting the syringe, wherein the interior comprises at least one ledge for resting the syringe in an inverted position within the holder to prevent further insertion of the plunger during centrifugation, further wherein the syringe holder is sized for insertion in a centrifuge rotor.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: August 27, 2013
    Inventor: Lanny Johnson
  • Patent number: 8512637
    Abstract: A device for receiving a sample carrier is provided. The device includes an opening for receiving part of the sample carrier and a cutter for removing a part of the sample carrier. The cutter is coupled to a lid, which is movable to allow the cutter to make an incision in the sample carrier and, at the same time, to close at least part of the opening left open after receipt of the sample carrier. The disclosure further relates to a system comprising such a device and a method for operating such a device.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: August 20, 2013
    Assignee: Biocartis SA
    Inventors: Harmina Zeijlstra, Ronald De Gier, Marloes M. E. B. Van De Wal, Ronaldus M. H. Steyvers, Astrid E. Visser
  • Patent number: 8496891
    Abstract: A reaction container holder capable of inhibiting the lowering of the transfer efficiency of heat transferred from a rotating member to a bottom surface of a reaction container, and an analyzer comprising the reaction container holder, are provided. In a reaction container holder comprising: a retaining member unit comprising a plurality of container retaining sections for retaining reaction containers, which house a reaction liquid containing a reagent and a specimen; and a circular rotating member for detachably fixing the unit from above and rotating, the holder keeping the container at a constant temperature by transferring heat from a heat source through the rotating member to the container, the rotating member comprises a level difference section, an upper surface of which is positioned below a bottom surface of the container retained by the unit and above a bottom part of the section, when the retaining member unit is fixed.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: July 30, 2013
    Assignee: Beckman Coulter, Inc.
    Inventor: Chikara Kuroda
  • Patent number: 8480957
    Abstract: Gas detector tubes may be used to determine a concentration of target gases in air. The gas detector tubes described may be read either by and optical reader or visually by the user. A gas detector tube reader having an optical reader capable of reading a length of stain, a color change and color density of a reagent in a gas detector tube. The gas detector tube may further comprise sensors for measuring the environmental conditions during sampling.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: July 9, 2013
    Assignee: Nextteq LLC
    Inventors: Bryan I. Truex, Gueorgui Mihaylov
  • Patent number: 8460620
    Abstract: A specimen collection container includes inner and outer tubes. The inner tube includes a bottom end, a top end, and a sidewall extending therebetween defining an interior. The sidewall includes an inner surface and an outer surface having at least one annular protrusion extending therefrom. The inner tube includes at least one funnel portion adjacent the top end for directing a specimen into the inner tube interior, and an annular ring disposed about a portion of the outer surface of the sidewall adjacent the top end. The outer tube includes a bottom end, a top end, and a sidewall extending therebetween, the sidewall having an outer surface and an inner surface defining an annular recess adapted to receive a portion of the annular protrusion therein. The inner tube is disposed within the outer tube and a portion of the top end of the outer tube abuts the annular ring.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: June 11, 2013
    Assignee: Becton, Dickinson and Company
    Inventors: Benjamin R. Bartfeld, Robert G. Ellis, Robert S. Golabek, Jr., Nancy Dubrowny, Girish Parmar, Paul Holmes, Alex Blekher, Michael Delk
  • Patent number: 8420013
    Abstract: Pure water is sucked from an acid adding flow line into a syringe and discharged from a drain flow line to clean the acid adding flow line, and then a carrier gas from a gas pipe is supplied to the acid adding flow line by the syringe to dry the acid adding flow line. A sample water collecting flow line is also cleaned and dried in the same manner. A TOC measurement flow line is cleaned with cleaning water sucked from a cleaning water flow line into the syringe, then a carrier gas from the gas pipe is supplied to the TOC measurement flow line by the syringe to clean and dry a flow line through which sample water flows in an organic matter oxidative decomposition unit from the TOC measurement flow line.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: April 16, 2013
    Assignee: Shimadzu Corporation
    Inventor: Shinsuke Inoue
  • Patent number: 8377397
    Abstract: A combustion tube comprises a generally cylindrical body with an outwardly extending annular tube stop spaced from one end of the combustion tube for engaging a combustion tube mounting assembly and fixing the tube in a precise position. Near the opposite end of the tube is an enlarged opening for receiving an upper seal assembly of a combustion furnace with the outer annular shoulder of the upper end of the tube having a rolled edge to facilitate the insertion of the tube through the seal in the upper seal assembly of the furnace. The combustion tube is made of quartz glass to withstand the temperatures encountered in the furnace. The combustion tube is specifically designed and adapted to be precisely positioned in an induction furnace with an easy tube removal system for the furnace.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: February 19, 2013
    Assignee: Leco Corporation
    Inventor: Gordon C. Ford
  • Patent number: 8372352
    Abstract: A drum type container for analytical elements comprises a casing defining a compartment with a plurality of portions for receiving respective ones of the analytical elements. The container further comprises a base assembly to which the casing is rotatably mounted. The base assembly includes a dispenser mechanism for dispensing the glucose test strips from the casing and a locking mechanism for maintaining an alignment of a selected one of the compartment portions with the dispensing mechanism.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: February 12, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Frank A. Chan
  • Patent number: 8361417
    Abstract: Some embodiments include a valve positioned within a test tube to maintain a separation between components of liquid with different densities after centrifugation. The valve preferably includes a cylindrically shaped housing with a conical plug configured to nest within the housing. The plug is not in contact with the housing during centrifugation, but comes into position post-centrifugation.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: January 29, 2013
    Inventors: Mehdi Hatamian, Mehrtosh Ghalebi, Matin Ebneshahrashoob
  • Patent number: 8343426
    Abstract: The present invention includes a separable test tube for use in a centrifugal separator that does not need to separately transfer separation liquid to another test tube for a second separation after a first separation. The separable test tube includes a first tube including a first coupling portion, a second coupling portion, and an adjustment portion. A second tube includes a first body part, a first space portion, a first packing fastener, a third coupling portion which engages the first coupling portion, and an adjustment groove into which the adjustment portion is inserted. A third tube includes a second body part having a second space portion, a second packing fastener, and a fourth coupling portion which engages the second coupling portion. First and second watertight members are coupled to the first and second coupling portions, respectively. First and second packings are coupled to the first and second packing fasteners, respectively.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: January 1, 2013
    Inventor: Hyo Seop Song
  • Patent number: 8329105
    Abstract: A lightweight, compact, easy-to-use, portable furnace used for quickly assaying crushed ore samples in the field and used by prospectors, miners, and geologists. The portable furnace can also be used for smelting precious metals and refining and recycling different metals. The furnace includes a metal stand having a stand base with a first end portion with a dish opening therein and a second end portion with an upwardly folded heat shield. The heat shield includes a nozzle groove therein for receiving a gas nozzle. The gas nozzle is part of a gas blow torch having a handle and a gas tank. The stand base also includes first and second sides folded downwardly for holding the metal stand above a flat surface. A bottom of a scorifying dish is received in the dish opening. A cupel is received inside the open top of the scorifying dish. The cupel is adapted for receiving a crushed ore sample therein to be assayed. A dish lid is received on top of the scorifying dish.
    Type: Grant
    Filed: January 20, 2009
    Date of Patent: December 11, 2012
    Inventors: Richard E. Sweeny, William B. Lewelling