Patents Examined by Juliet Einsmann Switzer
  • Methods of identification and isolation of polynucleotides containing nucleic acid differences
    Patent number: 6632610
    Abstract: The present invention is directed to methods of isolation of related polynucleotides harboring nucleic acid difference within a polynucleotide sample. The method will be useful in detecting and identifying alternative splicing events and corresponding splicing isoforms and to detect genomic DNA differences between genomes. The method according to the present invention is based on the use of a single-stranded trap. The single-stranded trap preferably involves the use of single-strand binding protein.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: October 14, 2003
    Assignee: Gensat S.A.
    Inventor: Gilbert Thill