Abstract: An apparatus has an upright gantry. A tube arm assembly and a compression arm assembly are rotatably coupled to the gantry. The tube arm assembly independently rotates relative to the compression arm assembly. A controller disposed on the gantry is operably connected to at least one of the tube arm assembly and the compression arm assembly.

Abstract: Systems and methods are disclosed for monitoring anatomic position of a human subject and modifying a radiotherapy treatment based on anatomic position changes, as determined with a regression model trained to estimate movement of a region of interest. Example operations for movement monitoring and therapy control include: obtaining 3D image data for a subject, which provides a reference volume and at least one defined region of interest; obtaining real-time 2D image data corresponding to the subject, captured during the radiotherapy treatment session; extracting features from the 2D image data; producing a relative motion estimation of a region of interest with a machine learning regression model, the model trained to estimate a spatial transformation from the 2D image data based on training from the reference volume; and controlling a radiotherapy beam of a radiotherapy machine used in the radiotherapy session, based on the relative motion estimation.

Abstract: Radiation treatment planning includes accessing values of parameters such as a number of beams to be directed into sub-volumes in a target, beam directions, and beam energies. Information that specifies limits for the radiation treatment plan are accessed. The limits include a limit on irradiation time for each sub-volume outside the target. Other limits can include a limit on irradiation time for each sub-volume in the target, a limit on dose rate for each sub-volume in the target, and a limit on dose rate for each sub-volume outside the target. The values of the parameters are adjusted until the irradiation time for each sub-volume outside the target satisfies the maximum limit on irradiation time.

Abstract: Disclosed herein are methods for radiotherapy treatment plan optimization for irradiating one or more target regions using both an internal therapeutic radiation source (ITRS) and an external therapeutic radiation source (ETRS). One variation of a method comprises iterating through ITRS radiation dose values and ETRS radiation dose values to attain a cumulative dose that meets prescribed dose requirements. In some variations, an ITRS is an injectable compound that has a targeting backbone and a radionuclide, and images acquired using an imaging compound that has the same targeting backbone as the injectable compound can be used to calculate the radiation dose deliverable using the injectable ITRS, and also to calculate firing filters for delivering radiation using a biologically-guided radiation therapy (BGRT) system. Image data acquired from a previous treatment session may be used to adapt the dose provided by an ITRS and/or ETRS for a future treatment session.

Abstract: Method include emitting x-rays from an x-ray source, directing a first portion of the x-rays through an object grating situated adjacent to an object while the object is scanned relative to the object grating along a scan direction, directing a second portion of the x-rays through the object and subsequently through a detector grating without transmitting through the object grating, wherein the object grating and detector grating are adjacently arranged in a field of view of the x-rays sequentially with respect to each other in the scan direction, and receiving the first portion transmitted through the object and object grating with a first portion of a detector and receiving the second portion transmitted through the object and the detector grating with a second portion of the detector adjacent to the first portion of the detector. Systems are also disclosed, along with related techniques for beam hardening correction.

Abstract: A tumor positioning method includes obtaining projection images of a tumor at different angles; and registering the projection images with an initial reference image to obtain a first offset. If it is determined that a virtual reacquisition operation needs to be performed according to the first offset, the method further includes generating a first reference image according to the first offset; and registering the projection images with the first reference image to obtain a second offset. If it is determined that the operation does not need to be performed according to the second offset, the method further includes outputting a first accumulated offset being a sum of the first and second offsets. The method may solve problems of long time consuming and the service life of a treatment couch and acquisition devices being reduced due to repeatedly moving the treatment couch and repeatedly acquiring the X-ray projection images.

Abstract: The present disclosure provides a substance identification device and a substance identification method. The substance identification device comprises: a classifier establishing unit configured to establish a classifier based on scattering density values reconstructed for a plurality of known sample materials, wherein the classifier comprises a plurality of feature regions corresponding to a plurality of characteristic parameters for the plurality of known sample materials, respectively; and an identification unit for a material to be tested, configured to match the characteristic parameter of the material to be tested with the classifier, and to identify a type of the material to be tested by obtaining a feature region corresponding to the characteristic parameter of the material to be tested.

Abstract: A microscope system for flexibly, efficiently and quickly inspecting patterns and defects on extreme ultraviolet (EUV) lithography photomasks. The system includes a stand-alone plasma-based EUV radiation source with an emission spectrum with a freestanding line emission in the spectral range from 12.5 nm to 14.5 nm has a relative bandwidth of ?/??>1000, means for the broadband spectral filtering ?/??<50 for selecting the dominant freestanding emission line, means for suppressing radiation with wavelengths outside of the EUV spectral region, zone plate optics for magnified imaging of the object with a resolution which corresponds to the width of an outermost zone of the zone plate, a numerical aperture corresponding to more than 1000 zones, and a EUV detector array for capturing the patterned object.

Abstract: The present disclosure provides a back scattering inspection system and a back scattering inspection method. The back scattering inspection system includes a frame and a back scattering inspection device. The rack includes a track arranged vertically or obliquely relative to the ground, and a space enclosed by the track forms an inspection channel; and the back scattering inspection device includes a back scattering ray emitting device and a back scattering detector, and the back scattering inspection device is movably disposed on the track for inspecting an inspected object passing through the inspection channel. The back scattering inspection system can perform back scattering inspection on a plurality of surfaces of the inspected object.

Abstract: Disclosed herein are systems and methods for iteratively training artificial intelligence models using reinforcement learning techniques. With each iteration, a training agent applies a random radiation therapy treatment attribute corresponding to the radiation therapy treatment attribute associated with previously performed radiation therapy treatments when an epsilon value indicative of a likelihood of exploration and exploitation training of the artificial intelligence model satisfies a threshold. When the epsilon value does not satisfy the threshold, the agent generates, using an existing policy, a first predicted radiation therapy treatment attribute, and generates, using a predefined model, a second predicted radiation therapy treatment attribute. The agent applies one of the first predicted radiation therapy treatment attribute or the second predicted radiation therapy treatment attribute that is associated with a higher reward.

Abstract: An apparatus and method for characterisation of a sample via spectroscopy and/or imaging. The apparatus comprises a first detector for imaging or spectroscopy, a second detector for imaging or spectroscopy, and a toroidal capacitor type electrostatic energy analyser. The toroidal capacitor type electrostatic energy analyser comprises a first and a second entrance aperture arranged such that charged particles emitted from a sample and passing through the first entrance aperture traverse a first trajectory through the toroidal capacitor type electrostatic energy analyser to be incident at the first detector, and charged particles emitted from a sample and passing through the second entrance aperture traverse a second trajectory through the toroidal capacitor type electrostatic energy analyser to be incident at the second detector.

Abstract: An analyzer includes a wavelength-dispersive X-ray spectrometer and a control unit that controls the wavelength-dispersive X-ray spectrometer, the control unit performing: processing of acquiring an analysis result of preparatory analysis performed on a specimen to be analyzed; processing of setting spectroscopic conditions for WDS analysis using the wavelength-dispersive X-ray spectrometer based on the analysis result of the preparatory analysis; and processing of performing the WDS analysis on the specimen to be analyzed under the set spectroscopic conditions.

Abstract: It is provided a method for determining arc costs. The method comprises the steps of: determining a plurality of beam orientations; evaluating a set of at least one cost function comprising an intermediate exposure cost function that is evaluated by performing the substeps of: projecting the at least one target volumes on a beam plane; determining an alignment angle based on a collimator angle value; finding any intermediate area in the beam plane along the alignment angle between areas of the at least one target volume projection; determining a value of the intermediate exposure cost function. The method further comprises the steps of: finding a plurality of arcs, wherein each arc comprises a sequence of a plurality of beam orientations; and calculating, for each arc in the plurality of arcs, at least one arc cost based on the cost function values of the beam orientations of the arc.

Abstract: This disclosure presents systems and processes to collect elemental composition of target fluid and solid material located downhole of a borehole. Waveguides can be utilized that include capillary optics to deliver emitted high energy into a container or a conduit and then to detect the high energy. A source waveguide can be used to emit the high energy into the target fluid and a detector waveguide can collect resulting measurements. Each waveguide can include a protective sheath and a pressure cap on the end of the capillary optics that are proximate the target fluid, to protect against abrasion and target fluid pressure. In other aspects, a pulsed neutron tool can be utilized in place of the waveguides to collect measurements. The collected measurements can be utilized to generate chemical signature results that can be utilized to determine the elemental composition of the target fluid or of the solid material.

Abstract: The invention relates to a position indicator for a system for moving a patient in a non-invasive therapy system, wherein the system for moving includes a patient support arranged outside a treatment space of a medical apparatus of the non-invasive therapy system, a treatment table arranged inside the treatment space in the medical apparatus, and a patient bed movable in a longitudinal direction from the patient support to the treatment table and back by means of activation of a transferring mechanism, wherein the position indicator comprises a number of light emitting elements arranged in the patient support and each being arranged to receive activation signals instructing a receiving light emitting element to emit light to indicate positions for treatment equipment.

Abstract: Provided is an X-ray tube, including: an electron-beam emitting unit; a target having a first surface and a second surface; a solid heat diffusion member fixed onto the second surface of the target; and a flow-path forming member, which is arranged on a side of the solid heat diffusion member, the side being opposite to the target, and that is configured to define a film flow path in which a cooling fluid forms a film flow that is parallel to a surface shape of the solid heat diffusion member. A protruding portion protrudes toward the side of the solid heat diffusion member, which is opposite to the target. The film flow path has a shape extending along at least a part of a surface of the protruding portion.

Abstract: A method and system for detecting an image of an object in an analyzer-based system with a polychromatic x-ray beam from an x-ray source, wherein an analyzer crystal and a detector simultaneously acquire a rocking curve of the x-ray beam for all energies of the x-ray beam. The x-ray beam is diffracted through the object using an asymmetrical monochromator. A detector movement is synchronized with one of the x-ray source or the object. The synchronization includes moving the detector at a first rate that is different than a second rate of the object or the x-ray source, wherein a ratio between the first rate and the second rate is determined by the magnification of the system.

Abstract: Disclosed herein are radiotherapy methods and systems that can display a workflow-oriented graphical user interface(s). A method comprises presenting a plurality of pages for display, each corresponding to a stage of a radiotherapy treatment for a patient; in response to receiving an indication that a surface of a patient is aligned, retrieving, from a radiotherapy file, a first image of an internal target aligned in accordance with treatment attributes; receiving a second image of the internal target; overlaying on a first page of the plurality of pages, the first image and the second image, the first page displaying a direction to position the internal target in the second image to align with the internal target in the first image; and when the internal target is aligned, presenting for display a second page of the plurality of pages corresponding to a subsequent stage of the radiotherapy treatment for the patient.

Abstract: The present invention relates, in part, to methods of using X-ray fluorescence (XRF) spectrometry for analyzing (e.g., measuring) the binding of a soluble target to an insoluble material.

Abstract: A back illuminated sensor is included as a collector component of a detector for use in intraoral and extraoral 2D and 3D dental radiography, digital tomosynthesis, photon-counting computed tomography, positron emission tomography (PET), and single-photon emission computed tomography (SPECT). The disclosed imaging method includes one or more intraoral or extraoral emitters for emitting a low-dose gamma ray or x-ray beam through an examination area; and one or more intraoral or extraoral detectors for receiving the beam, each detector including a back illuminated sensor. Within the detector, the beam is converted into light and then focused and collected at a photocathode layer without passing through the wiring layer of the back illuminated sensor.