Patents Examined by Jyothsnh Venkat
  • Method for making liposomes of enhanced entrapping capacity toward foreign substances to be encapsulated
    Patent number: 5393530
    Abstract: Liposome vesicles are prepared containing water or very dilute solutions encapsulated therein. These "empty" liposomes are suspended in a carrier liquid containing, dispersed therein, substances of interest to be loaded into the vesicles and incubated for a period of time at temperatures above the lipids transition temperature, whereby loading by transmembrane permeation occurs in high yields.
    Type: Grant
    Filed: June 22, 1992
    Date of Patent: February 28, 1995
    Assignee: Bracco International B.V.
    Inventors: Michel Schneider, Herve Tournier, Roland Hyacinthe, Christian Guillot, Bernard Lamy