Abstract: The present disclosure provides synthetic modular polypeptide libraries and nucleic acids encoding such synthetic modular polypeptide libraries. Also provided are methods of making synthetic modular polypeptide libraries and nucleic acids encoding synthetic modular polypeptide libraries. Methods of screening a synthetic modular polypeptide library to identify a selected phenotype associated with a member of a synthetic modular polypeptide library are also provided where such methods find use in both in vitro and in vivo assays.

Abstract: Systems, methods and compositions provided herein relate to the preparation of nucleic acid libraries. Some embodiments include the preparation of nucleic acid libraries by ligation of single-stranded nucleic acids.

Abstract: The present invention provides a method for efficiently obtaining a complex in which a gene (mRNA) and a peptide as a translation product thereof are linked via a peptide receptor molecule, and utilization thereof. In the method of the present invention, at least one 2?-modified nucleoside derivative is introduced into a 5? end side of an antisense strand of a template DNA.

Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: A method for displaying proteins and peptides is disclosed in which individual proteins or peptides remain associated with the DNA encoding them. Proteins or peptides can be generated by in vitro translation of DNA templates, either free in solution or arrayed on a solid support, such that the proteins or peptides remain immobilized on their DNA templates. In particular, high throughput sequencing can be combined with high throughput functional characterization of encoded proteins and peptides, wherein the identity of each protein or peptide is determined by DNA sequencing, and functional studies are carried out directly on each protein or peptide while immobilized on the DNA template encoding it. The methods of the invention should find numerous applications, for example, in high throughput genetic or pharmacological screening, epitope mapping, and protein engineering and directed evolution.

Abstract: The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics.

Abstract: In an image forming apparatus which tranfers a toner image to a sheet in accordance with image information, a first connector, is fixed to the outside of a developing device which supplies a developing agent to the apparatus. The first connector electrically connects the body and the developing device. A second connector, adapted to be connected to the first connector, is fixed to a mounting portion for holding the developing device in the apparatus. When the developing device is attached to the mounting portion, the first and second connectors are connected to each other. The apparatus also includes a movable handle which would or would not allow a removable lid to fully close.

Abstract: A copier/printer with a light/lens system providing copies of documents, a raster output scanner providing prints in response to image signals, a source of screen image signals, and control means for operating both the light/lens system and the raster output scanner together while accessing the screen image signals so that the raster output scanner creates a dot matrix screen on the photoreceptor over which the latent image of the document being copied is placed by the light/lens system.

Abstract: A recording apparatus wherein a bottom of a body of the apparatus having conveyor device for conveying recording paper is freely opened and closed to open the conveyor device when the body is lifted up. A body frame composed of a front panel, a rear panel and a bottom plate of the recording apparatus is molded by a resin as a unit.

Abstract: A system for loading sheet materials on a rotary drum, having carrier for carrying sheet materials to the drum, a mechanism for catching the leading end of the sheet materials on the drum, and a presser member for pressing the sheet materials to said drum rotating, so as to wind said sheet materials around said drum, wherein said system involves a dampening arrangement for dampening the space between sheet materials and the drum surface, which is mirror finished, so as to contact said sheet materials with said peripheral surface of said drum.

Abstract: A printed circuit assembly includes surface mounted circuit components held in place on a printed circuit board by a rigid connection. The outwardly extending leads of the circuit component are bonded to conductive areas of the board by an electrically conducting flexible adhesive. The combination of a rigid mechanical connection between the body portion of the circuit component and the board and a flexible, electrically conductive connection between each lead end and the board provides an arrangement capable of withstanding shock loading, as well as vibrational and bending forces to which the assembly might be subjected. The assembly lends itself to relatively inexpensive circuit boards produced by printing techniques, typically including applied metal buses that serve as low resistance shunts to the power connections of the circuit components.

Abstract: An apparatus in which a tubular member mounted on a shaft moves linearly in response to rotation of the shaft. A cam is mounted on the shaft and in engagement with bearings mounted on the interior surface of the tubular member. As the shaft rotates, the cam moves in unison therewith to move the tubular member linearly. The linear movement of the tubular member moves a portion of a photoconductive belt between an operative position, adjacent a developer unit, and an inoperative position, spaced from the developer unit.

Abstract: A RAM system suitable for use in copier and printing machines having a relatively slow (i.e. 2 inches per second) process speed while avoiding the prior art problem of excess oil application, particularly outside the copy area. The RAM system contains a supply of release agent material which permits operation without frequent addition of oil to the supply yet without fear of oil spillage.The RAM system comprises a very thin (i.e. 0.006 inches thick) wick one end of which contacts a supply of release agent material such as low viscosity silicone oil while an intermediate portion thereof is held in contact with a fuser roll member.An oil reservoir containing a pad is provided. The pad serves as the supply of oil for the one end of the wick. The majority of the oil is contained in the pad, therefore, the problem of spillage found in prior art devices is obviated.

Abstract: Electric relay comprising one or more relay tongues, a relay contact cooperating with the respective tongue and an electromagnet actuating the respective tongue. A relay tongue unit (3) is then integral with at least one relay tongue (4), which has in one part an area reducing cross sectional dimension and is formed at its end opposite to the free end with a material cut portion (23) serving as an electric fuse. The surface of the relay contact (6) cooperating with the contact point (5) of the relay tongue is movable to a limited extent relative to this and, moreover, the electromagnet (9) actuating the relay tongue (4) consists of two composite iron plates (31, 32) electrically insulated from each other which have each, insulated from each other, an electric connection (34) integral with the iron plate, the coil (37) fed by the operating current of the electromagnet (9) being connected with one of its conducting ends (38) to one iron plate (31) and with its other end (39) to the other iron plate (32).

Abstract: Disclosed is a pressure transducer comprising a pressure sensitive silicon die having a front side exposing piezoresistive means and comprising means for flip-chip mounting the die to a pressure vessel. The transducer further comprises a pressure vessel having an aperture, the pressure vessel comprising means for flip-chip mounting the die over the aperture. The die is flip-chip mounted over the aperture in the pressure vessel, and there is a hermetic seal between the pressure vessel and the die.

Abstract: In a circuit breaker includes a fixed contactor, a moving contactor subjected to a switching operation of a switching mechanism, a heater connected to the moving contactor and disposed in such a manner as to extend along a fixed core and a moving core pivotally supported by the fixed core, the fixed contactor is formed in a J-shape and is interposed between an insulating member disposed on the fixed contactor in such a manner as to extend along the side of the fixed contactor facing the moving contactor and a demagnetizing member disposed in such a manner as to extend along the bent inner surface. The circuit breaker includes also an operation time adjusting mechanism engaging with the moving core and capable of adjusting the operation time of the moving core, and a casing storing therein the constituent elements. The operation time adjusting mechanism is brought into abutment against an adjustment portion formed on the moving core, and is detachably mounted on the casing.

Abstract: An electrophotographic printing machine in which indicia are printed on a sheet in at least two different colors. An electrostatic latent image is recorded on a photoconductive member and developed with a liquid developer material of one color. The latent image is neutralized and ions projected onto the photoconductive member in an image wise pattern to record another latent image. This latent image is developed with a liquid developer of another color. Both liquid images are transferred substantially simultaneously to a sheet to print indicia in two colors thereon.

Abstract: Disclosed is an electronic copier, lazer printer or like imaging apparatus for developing a latent image provided on a photoconductive element by a developing device of the type using a toner cartridge, thereby turning the latent image into a visible toner image. A body of the apparatus consists of an upper part and a lower part, the former being openably supported by the latter. A positioning frame is supported by the lower body part in such a manner as to rotatable up and down. An image carrier unit which includes at least the image carrier and a developing unit which includes at least the developing device are detachably mounted on the positioning frame and mounted to and dismounted from the frame independently of each other.

Abstract: A light transmitting plate holding construction of an image forming device comprises an elongated optical filter plate, a holder for holding the optical filter plate and a holder mounting means for mounting the holder on a body of an image forming device, wherein the holder is composed of a pair of holder portions clamping the optical filter plate therebetween in opposition, and each of the holder portions includes an internally faced U-shaped portion engaging both long sides of the optical filter plate, and an externally face U-shaped portion extending integrally from one opposed edge of the internally face U-shaped portion.

Abstract: In a method for producing a reed relay, and a reed relay produced in accordance therewith, for switching r.f. currents at high voltages, it is proposed to arrange the coil, which is wound upon a normal bobbin with flanges on both sides, within a low-ohmic coil shielding by mounting the bobbin with the coil in an outer tube of brass, fitting an inner tube, likewise of brass, in the bobbin and connecting the two tubes by annular end disks placed on the two ends and joined with the tubes by pressing. The whole assembly comprising the bobbin, the coil and the shielding is then mounted on a two-piece bobbin carrier, and the vacuum glass tube of the r.f. reed switch is inserted into the bearing tube of the bobbin carrier and preferable fixed therein by means of a silicone hose.