Patents Examined by Kagnew H Gebreysus
  • Compositions for generation of immune tolerance to specific antigens
    Patent number: 10265416
    Abstract: Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: April 23, 2019
    Assignee: École Polytechnique Fédérale de Lausanna (EPFL)
    Inventors: Jeffrey A. Hubbell, Stephan Kontos, Karen Y. Dane