Abstract: A controller for displaying a puncture site of an intra-atrial septum for heart repairs includes a memory and a processor (710). The processor (710) executes instructions (784) to perform a process based on image data of a heart that includes a mitral valve and an intra-atrial septum. The process includes defining a mitral valve annulus plane along a mitral valve annulus of the mitral valve and a normal vector perpendicular to the mitral valve annulus plane. The process also includes defining an offset plane that intersects with the intra-atrial septum and that is parallel to the mitral valve annulus plane. A safe zone for the puncture site is identified and displayed on the intra-atrial septum. The safe zone is between a lower boundary plane (456) and an upper boundary plane (455) that are each parallel to the offset plane by specified distances.

Abstract: Disclosed herein is a system for navigated punction, biopsy or ablation comprising a mobile electromagnetic field generator for generating an electromagnetic navigation field which is connected to an apparatus for medical imaging, a needle-like instrument (16), comprising a sterile distal portion (22) and an optionally non-sterile proximal portion (20), a removable protection device (30) for encapsulating the sterile distal portion (22), a sensor (38) suitable for carrying out measurements allowing for determining the position of the sensor (38) within the navigation field, and a sensor carrier (26). The sensor carrier (26) comprises an elongate carrier body (36) having proximal and distal ends. The sensor (38) is attached to or enclosed by said carrier body (36) close to its distal end.

Abstract: Systems and methods for three-dimensional imaging, modeling, mapping, and/or control capabilities in compact size suitable for integration with and/or augmentation of robotic, laparoscopic, and endoscopic surgical systems. The systems including at least one optical source configured to project onto a surgical or endoscopic environment, and at least one camera positioned to capture at least one image of the surgical or endoscopic environment.

Abstract: A method and device for detecting inflammation activity of a tissue. The method includes: determining whether there is a possibility for tissue inflammation; and when there is a possibility for tissue inflammation, determining the inflammation activity of a tissue according to tissue stiffness or a parameter reflecting tissue stiffness. The tissue stiffness or the parameter reflecting tissue stiffness can be detected by means of a non-invasive quantitative detection technique of tissue elastic modulus, avoiding defects caused by tissue biopsy, and can detect inflammation activity of a tissue non-invasively, continuously and accurately.

Abstract: Embodiments of the present disclosure relate to techniques for neuromodulation delivery. Based on image data acquired from the subject, control parameters controlling energy application of neuromodulating energy may be dynamically changed during the course of the delivery to maintain desired characteristics of the neuromodulating energy. For example, the beam of the neuromodulating energy may be dynamically adjusted to account for movement of an organ during breathing. In another embodiment, a desired region of interest is identified within the subject based on a trained neural network and the acquired image data.

Abstract: An OSS foreshortening detection system employing an interventional device (40) including a OSS sensor (20) having shape nodes for generating shape sensing data informative of a shape of OSS sensor (20). The system further employs a OSS foreshortening detection device (80) including a OSS shape controller (90) for reconstructing a shape of a portion/entirety of interventional device (40) derived from a generation of the shape sensing data by OSS sensor (20). Device (80) further includes a OSS foreshortening controller (100) for monitoring any foreshortening of the interventional device (40) within an image of the interventional device (40) including the OSS foreshortening controller (100) detecting a location of any occurrence of a foreshortening of the interventional device (40) within the image of interventional device (40) derived from the reconstruction of the shape of the portion/entirety of interventional device (40) by the OSS shape controller (90).

Abstract: The present invention relates to an ultrasound treatment device for HIFU and an ultrasound image, and to a control method therefor. The ultrasound treatment device comprises: a plurality of image converters disposed on one surface of a probe assembly to transmit ultrasound signals to a target and receive signals reflected by the target to create an ultrasound image; a plurality of high intensity focused ultrasound (HIFU) converters disposed on the surface of the probe assembly so as to be located in different positions from the image converters, wherein the HIFU converters transmit ultrasound signals to a target to generate heat energy, thereby treating a tissue within a focusing area; and a control unit performing control such that the difference between apertures of converter arrays constituted by the image converters and the HIFU converters, respectively, is less than a predetermined value.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more external optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The one or more optical emitters and the measurement apparatus may be moved together synchronously. The measurement apparatus may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: An ultrasound detection device comprising: an ultrasound receiver configured to generate a signal indicative of a pressure of ultrasound that impinges on the receiver; and a coded mask comprising an ultrasound-blocking material perforated by an array of a plurality of apertures, the apertures arranged such that when the coded mask is placed over the receiver between the receiver and a source of ultrasound in a predetermined lateral position, the ultrasound is transmitted from the ultrasound source to the receiver via a known unique pattern of active apertures of the plurality of apertures such that the signal that is generated by the receiver is a multiplexed signal.

Abstract: Methods and systems are provided for tracking anatomical features across multiple images. One example method includes outputting, for display on a display device, an annotation indicative of a first location of an identified anatomical feature of a first ultrasound image, the annotation generated based on a first output of a model and outputting, for display on the display device, an adjusted annotation based on a second output of the model, the second output of the model generated based on a second ultrasound image and further based on the first output of the model, the adjusted annotation indicative of a second location of the identified anatomical feature in the second ultrasound image.

Abstract: A surgical visualization system is disclosed. The surgical visualization system includes a control circuit communicatively coupled to a straight line laser source, a structured light emitter, and an image sensor; and a memory communicatively coupled to the control circuit. The memory stores instructions which, when executed, cause the control circuit to control the straight line laser source to project a straight laser line reference; control the structured light source to emit a structured light pattern onto a surface of an element of a surgical device; control the image sensor to detect the projected straight laser line and structured light reflected from the surface of the element of the surgical device; and determine a position of the element of the surgical device relative to the projected straight laser line reference.

Abstract: A surgical visualization system is disclosed. The surgical visualization system is configured to identify one or more structure(s) and/or determine one or more distances with respect to obscuring tissue and/or the identified structure(s). The surgical visualization system can facilitate avoidance of the identified structure(s) by a surgical device. The surgical visualization system can comprise a first emitter configured to emit a plurality of tissue-penetrating light waves and a second emitter configured to emit structured light onto the surface of tissue. The surgical visualization system can also include an image sensor configured to detect reflected visible light, tissue-penetrating light, and/or structured light. The surgical visualization system can convey information to one or more clinicians regarding the position of one or more hidden identified structures and/or provide one or more proximity indicators.

Abstract: An ultrasound imaging system computes real time physiological parameters from measurements of anatomical features in ultrasound image data using a neural network to identify the location of the anatomical features. In one embodiment, cardiac parameters are computed from endocardial wall tracings in M-mode ultrasound image data that are identified by the neural network.

Abstract: Methods, systems, and coaptation measurement devices as described herein include an elongate sensor body at the end of a proximal connecting member, and a plurality of sensors in an array across a face of the sensor body, wherein each sensor of the plurality of sensors is configured to detect if a portion of a heart valve is in contact with the sensor.

Abstract: The disclosure relates to a method and a tracking system for tracking a medical object. Herein, image data obtained by an imaging method and a predetermined target position is acquired for the medical object. The image data is used to detect the medical object automatically by an image processing algorithm and track the position thereof in a time-resolved manner. Furthermore, it is furthermore indicated when, or that, the detected medical object has reached the target position. A plurality of the detected positions of the medical object and associated detection times are stored in a database.

Abstract: There is provided a computer implemented method for generating a three dimensional (3D) image based of fluorescent illumination, comprising: receiving in parallel by each of at least three imaging sensors positioned at a respective parallax towards an object having a plurality of regions with fluorescent illumination therein, a respective sequence of a plurality of images including fluorescent illumination of the plurality of regions, each of the plurality of images separated by an interval of time; analyzing the respective sequences, to create a volume-dataset indicative of the depth of each respective region of the plurality of regions; and generating a 3D image according to the volume-dataset.

Abstract: A system for delivering drugs or other molecules to the brain comprises an ultrasound imaging transducer configured to image structures such as the circle of Willis within a patient's head by way of a low attenuation acoustic window. The system includes a processor configured to register the ultrasound images to previously obtained images which also include the structures. The system includes ultrasound transducer elements operable to deliver ultrasound energy to a target region to cause the blood brain barrier to open. The system may include a drug delivery system that may be operated to deliver a drug to the patient in coordination with opening the blood brain barrier. Coordinates of the target region relative to the ultrasound imaging transducer are determined using registration information.

Abstract: An ultrasound device (10) is disclosed comprising a transducer arrangement (110) and an acoustically transmissive window (150) over said arrangement, said window comprising an elastomer layer (153) having conductive particles dispersed in the elastomer, the elastomer layer having a pressure-sensitive conductivity, the ultrasound device further comprising an electrode arrangement (160) coupled to said elastomer layer and adapted to measure said pressure-sensitive conductivity. An ultrasound system and arrangement including such an ultrasound device are also disclosed.

Abstract: Controlling an image appearance in ultrasound system comprises: providing a set of image appearance feature control parameters, each of which relates to an image appearance feature according to a pre-defined relation between a value scale of the said image appearance feature control parameter and an image appearance related to a certain condition of the corresponding image appearance feature; generating a function between the value of each image feature control parameter and the value of the standard workflow setting parameters of a combination of standard workflow setting parameters influencing the said image appearance feature; and varying automatically the value of the one or more of the standard workflow setting parameters of the combination of standard workflow setting parameters influencing an image appearance feature as a function of a variation of the value of the corresponding image appearance feature control parameters for obtaining the requested image appearance feature variation.

Abstract: An in vivo optical biopsy applicator of the vaginal wall for treatment planning, monitoring, and imaging guided therapy is described herein. The applicator may include an imaging probe operatively coupled to a laser ablation device. The applicator allows for non-invasive optical tissue monitoring in order to define pre- and post menopausal parameters, pre- and post-treatment microscopic changes, and offers an objective scientific tool in order to compare currently available medical, non-medicated, and energy-based treatment protocols.