Abstract: A stent delivery system can include a core member, a stent engagement member, and a stent. The core member can have a distal segment. The stent engagement member can have a generally tubular body positioned about the core member distal segment and can be rotatably coupled to the core member. The engagement member can include an inner layer that has a first durometer and an outer layer that has a second durometer less than the first durometer. The stent can extend along the core member distal segment such that an inner surface of the stent is engaged by the engagement member outer layer for facilitating rotation of the stent relative to the core member.

Abstract: Tissue compression devices having pressure indicators and methods of using the same. The tissue compression devices provide feedback to a user with respect to the pressure being applied to selected tissue at a selected location such as a radial artery to assist the user in applying the desired amount of pressure to the tissue (such as the pressure needed to achieve hemostasis at an access site). The pressure indication may be provided by a ring indicator that moves between two configurations (e.g., a concave configuration and a convex configuration), a bellow chamber in a housing, a bladder located below a bladder window, etc.

Abstract: A prosthetic aortic valve intended for native or valve-in-valve within bioprostheses includes an expandable support scaffold and valve leaflets disposed within an upper leaflet portion of the support scaffold. The valve leaflets within the upper portion may be located within the annulus (intravalvular), above the annulus, or above the native or prosthetic leaflets (supravalvular). The valve within a previously implanted degenerated heart valve such that a base or lower portion of the replacement valve is within the previously implanted valve and the upper portion is expanded within the aorta, the internal area of the valve can be increased and the hemodynamics of the valve improved. Alternatively, the valve may include separate upper and lower portions allowing the portions to be implanted sequentially if needed and the length and other characteristics of the valve to be adjusted based on patient anatomy and condition.

Abstract: This invention can be embodied in a device for occluding a cerebral aneurysm comprising a series of proximally-and-distally-connected coil loops. This invention can further comprise a stretchable mesh which spans the interiors of these loops. These loops (and the stretchable mesh) overlap to create a coil-and-mesh mass within the aneurysm sac which occludes the aneurysm.

Abstract: Mechanical thrombectomy apparatuses (devices, systems, etc.) and methods for positioning them within a vessel and using them to remove a thrombus, e.g., clot, from within a vessel. In particular, described herein are methods of advancing an inverting tractor thrombectomy apparatus having a tractor comprising a flexible tube of material that inverts over itself as it rolls over a distal end opening of an elongate inversion support by extending the tractor region and/or a puller coupled to the tractor distally beyond the end of the catheter. Also described herein are power-driven mechanical thrombectomy apparatuses.

Abstract: The invention relates to a snare device for catching an object, in particular for catching objects or foreign bodies in a human or animal body, said snare device comprising a hollow element, in particular a catheter, and a snare made of a flexible elastic shape-memory material, wherein the snare is movable relative to the hollow element and can be pulled into the hollow element and pushed out of it, and wherein the snare has an impressed original shape to which said snare return, when pushed out from the hollow element, as a result of the material stresses caused when it was pulled in, wherein the original shape of the snare has a twisted area, as a result of which a first loop and a second loop are formed, wherein the first loop is arranged substantially parallel to the longitudinal axis of the hollow element, and the second loop is at an angle with respect to the longitudinal axis of the hollow element, and which is characterized in that the snare thus deformed is introduced into the hollow element and is a

Abstract: A clip used to repair the tissue of a heart valve leaflet may include a shaft having a barb and a plurality of legs connected to the shaft. The plurality of legs may extend away from the barb in a first condition, and may extend towards the barb in a use condition. The clips may be delivered to the heart valve leaflet and applied to the same in a minimally invasive procedure using a transcatheter device. The device may be used to apply a single clip to the leaflet tissue or multiple clips.

Abstract: The invention relates to a surgical device (100) designed to be inserted into a stump of a hollow organ (40) of a person or animal in order to prepare a circular anastomosis, wherein the device (100) is designed without a stapling unit for producing a surgical stapled scam, wherein the device (100) has an instrument shaft (120) having a handle section (121, 300) and, at the end of time instrument shaft (120) away from the handle section (121, 300), a head section (130) that is or can be coupled to the instrument shaft (120) by means of a detachable coupling (113), wherein the handle section (121, 300) is designed for a user to hold the device (100), wherein the head section (130) has at least one first molded body (109) and a counter-pressure plate (111) of a surgical circular stapling device (160) connected to the first molded body (109), wherein the surgical device has fu least one first molded body (109) and one second molded body (108) between the handle section and the counter-pressure plate, the second

Abstract: A medical instrument includes a rod-shaped grasp portion at a base end thereof, a functional portion used in medical practice at a front end thereof, and a shape-memory portion including a rod-shaped shape-memory alloy provided between the grasp portion and the functional portion. The grasp portion includes a holding portion having a space in which one end of the shape-memory portion is inserted from the longitudinal direction. The instrument has a gap between an outer surface of the shape-memory portion and an inner surface of the holding portion, and in bending the shape-memory portion, the shape-memory portion is capable of deforming within the range of the gap. Then, by bending, the outer surface of the shape-memory portion comes into contact with an inner edge portion of an opening of the holding portion, and thereby restricts deformation of the shape-memory portion beyond the predetermined range.

Abstract: Embodiments of the present invention relate to surgical clamping devices and applicators for use therewith. Embodiments of the surgical clamping device comprise a body and a pair of clamping members extending from the body. An electronic controller housed within the body is coupled to control movement of at least one of the clamping members to control a pressure exerted by the clamping members on a blood vessel clamped therebetween. At least one blood flow sensor is mounted to at least one of the clamping members to detect blood flow in the blood vessel. The clamping members are locked in place when blood flow has been occluded or constricted to the desired extent.

Abstract: An occlusion system includes a delivery catheter having an elongate body defining a delivery lumen, and an occlusion device including a bundle of elongate occlusion wires configured for simultaneous delivery through the delivery lumen. At least a portion of each of the occlusion wires includes a shape memory material and has a preformed shape. The occlusion system includes a delivery configuration in which each of the occlusion wires is positioned within the delivery lumen, urged against the preformed shape, and substantially parallel to a longitudinal axis of the delivery lumen, and a post-deployment configuration in which each of the occlusion wires is released from the delivery lumen and conforms to the preformed shape. According to the preformed shape, each of the occlusion wires has a longitudinal segment remaining parallel to the longitudinal axis and a curved end providing an outward radial force with respect to the longitudinal axis.

Abstract: Provided is a fragmentation tip, an intraocular surgery device, a method for suppressing an occurrence of cavitation, and a cataract surgery method, which can suppress the occurrence of cavitation. The fragmentation tip, which is attached to an intraocular surgery device configured to apply ultrasonic vibration, includes: a cylindrical support portion configured to be mounted on the intraocular surgery device; and a cylindrical tip body provided at a distal end of the support portion to be in communication with an internal space of the support portion, wherein the tip body has a cross sectional shape having a length in a first direction that is larger than a length in a second direction that is orthogonal to the first direction, and vibration is applied to the support portion so that the tip body rotates back and forth about an axis of the tip body that passes through its center in the first and second directions.

Abstract: Tissue compression devices including a multi-chamber bladder that is retained within the tissue compression device, with the multi-chamber bladder being positioned in a bladder orifice in a base of a compression device body. The multi-chamber bladder includes at least one upper chamber located above the base and at least one lower chamber located below the base. The lower chamber is located between the base and a selected location on a patient when the compression device is positioned over selected tissue such as, e.g., a radial artery, as described herein.

Abstract: A combination double-barreled and debranching stent graft and methods for its use, where the stent graft comprises, a main body stent graft defining a single lumen with distal and proximal ends, a first bifurcation in the main body defining first and second lumens, the main body stent graft defines a tubular wall that is contiguous with the first and second lumens such that any fluid entering the main body stent graft must exit by entering one of the first or second lumens, (c) a second bifurcation within the first lumen defining a first leg and a second leg, (d) a third bifurcation within the first leg defining a third leg and a fourth leg, and (e) a fourth bifurcation within the second leg between about 10 mm and about 20 mm distal from the second bifurcation defining a fifth leg and a sixth leg.

Abstract: Disclosed herein is a variably flexible pipe including at least one flap member having variable flexibility and a tube formed of an elastically deformable material and accommodating the at least one flap member, and a manipulator having the same. The at least one flap member may include a plurality flap parts and a connection part to which one side of each of the plurality of flap parts is connected, and the tube changes pressure applied to the plurality of flap parts according to a controlled change of the inner pressure of the tube, thereby causing the variably flexible pipe to be effectively selectively maintained in a deformed state.

Abstract: A surgical system comprises an end effector for operating on tissue and a screen positioned around the end effector. The screen is fluidly coupled with a suction source by a conduit such as a tube. The screen is configured to communicate suction through the screen while preventing tissue from contacting the end effector. The screen is further configured to retract proximally relative to the end effector to thereby expose the end effector.

Abstract: A delivery system is provided for a self-expanding medical device. The delivery system has a handle assembly with a housing. The housing has a slot with a deployment knob extending therethrough. The self-expanding medical device is deployed by restraining the housing of the handle assembly and pulling on the deployment knob. This causes an outer sheath to withdraw proximally from an inner catheter to release the self-expanding medical device from a space between the outer sheath and inner catheter.

Abstract: A transcatheter valve prosthesis is disclosed that has a compressed, delivery configuration and an expanded configuration for deployment within a native heart valve. The valve prosthesis includes a self-expanding frame and a prosthetic valve component. The self-expanding frame includes a valve receiving portion defining an opening therethrough and first and second anchors at opposing ends of the valve receiving portion. The valve receiving portion is substantially planar and the first and second anchors are oriented substantially perpendicular to the valve receiving portion when the valve prosthesis is in the expanded configuration. The prosthetic valve component is disposed within the opening of the valve receiving portion and secured thereto.

Abstract: An apparatus configured for coupling two portions of tissue of a subject, such as two portions of a transected tendon. In some embodiments, the apparatus comprises a first and second helical element and a locking element. Each helical element is configured to be coupled to a portion of tissue, and the locking element is configured to couple the first helical element to the second helical element such that the helical elements are collinear.

Abstract: Device for treatments of endoscopic resection/removal of tissues including: a handpiece; an outer tubular element extending along a longitudinal axis including a proximal end, a distal end and a cutting opening at the distal end; an inner tubular element rotatably accommodated in the outer tubular element; the inner tubular element extending along a longitudinal axis and including a proximal end, a distal end and a cutting tip at its distal end; a guide for rotating/oscillating the inner/outer tubular elements with respect to one another; the guide including an electric motor and power-supply; a first clutch keyed on the inner tubular element substantially at the proximal end of the inner tubular element; a second clutch keyed on the distal end of the motor output shaft to axially slide on the motor output shaft; and at least one elastic element to push the second clutch to couple with the first clutch.