Abstract: New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
Type:
Grant
Filed:
September 29, 2003
Date of Patent:
October 30, 2012
Assignee:
Novartis AG
Inventors:
Payman Amiri, Wendy Fantl, Barry Haskell Levine, Daniel J. Poon, Savithri Ramurthy, Paul A. Renhowe, Sharadha Subramanian, Leonard Sung
Abstract: There is provided compositions and methods for providing a natural appearance, healthy glow, and other aesthetic benefits to the skin. One composition has a shade-matched pearlescent component. Another composition has a blend of a shade-matched pearlescent component and a shade-matched pigment component. Preferably, the blend is incorporated into an emulsion, a powder, cream-to-powder cosmetic, a gel, a pomade, a solution, a stick, suspension, or a wet/dry foundation.
Abstract: A process for preparing graft copolymers of polyvinyl esters by polymerization of a) at least one vinyl ester of aliphatic C1-C24-carboxylic acids in the presence of b) polyethers which are solid at room temperature and have the general formula I, c) and, where appropriate, at least one other monomer using a free-radical organic initiator system, wherein liquid polyalkylene glycol is used as solvent for the free-radical initiator system (feed).
Type:
Grant
Filed:
January 24, 2001
Date of Patent:
December 16, 2008
Assignee:
BASF Aktiengesellschaft
Inventors:
Maximilian Angel, Michael Gotsche, Karl Kolter
Abstract: Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising minoxidil, and methods for using the novel compositions for treating and preventing hair loss in a region of a patient.