Abstract: A power injector is provided for injecting fluid from a replaceable syringe and through an injection tube into the body of an animal. The syringe includes one or more operator-removable and interchangeable syringe mounting heads, at least one of which mounts syringes of a rear loadable type. Preferably an alternative head is provided that accepts front loadable syringes. The mounting head includes an opening and a moveable syringe holder that preferably pivots open to receive a syringe from the back of the holder and pivots closed to orient the rear of the syringe over the ram. The holder has a slot therethrough having a width sufficient to permit an injection tube attached to the syringe nozzle to be moved transversely through the slot to permit the syringe to be removed from the holder without disconnecting the tube from the orifice of the syringe and without withdrawing the tip of the tube rearwardly through the opening.

Abstract: A liquid removal system having an interface device and a vacuum source are described. The interface device has a porous membrane with an entrance zone on one side. The vacuum source maintains a vacuum on the side of the membrane opposite the entrance zone when the membrane is wetted. Liquid which contacts the wetted porous membrane is removed from the interface device by the vacuum source.

Abstract: A catheter assembly having a sheath, which includes a side wall enclosing an interior bore, and a distal region. The assembly also has a bendable catheter tube, which is carried for sliding movement in the interior bore. A pull wire also runs through the interior bore of the sheath, preferably within a lumen. The catheter tube has a distal portion with a coupling which joins the distal portion of the catheter tube and the distal portion of the pull wire. Relative movement of the pull wire and the sheath causes bending of the catheter tube outwardly through the opening, in response to sliding movement of the catheter tube within the interior bore toward the distal region of the sheath.

Abstract: A device for forming a leakproof closure on the terminus of a tubing having an elastic wall. The device consists of a plug insertion tool and a plug. The plug is a elongate member having a convex distal end and a proximal end. The plug insertion tool has a handle portion which is dimensioned to be grasped by a user for manipulation. The distal end of the insertion tool has a rod projecting axially therefrom which is adapted to releasably engage the proximal end of the plug. The plug is dimensioned to fit snugly within the elastically distended lumen of the tubing. In operation, the plug insertion tool is releasably attached to the proximal end of the plug by engagement means such as mating threads and the distal end of the plug inserted into the open end of the tubing and advanced by means of the insertion tool. The intralumenal portion of the plug forms a leakproof seal with the elastic wall of the tubing.

Abstract: A method for inserting an implant into a patient utilizing an apparatus comprising a cartridge having a body with a central bore. The body comprises at its proximal end a retention shoulder or hub adapted for retention by an insertion tool. The body further comprises a closure plug received in the proximal end of the bore that seals the bore and that has an exposed surface to engage a plunger rod from an insertion tool. The body further comprises a sealed distal tip of decreasing diameter from the outer surface of the body that terminates in a point adapted for penetrating a pre-existing body orifice or for piercing tissue during insertion into a patient. The tip is frangible into a plurality of segments under pressure exerted by the distal end of the implant, allowing the implant to emerge from the cartridge.

Abstract: A method and apparatus for occlusion monitoring in a flow circuit using pressure waveform analysis. The flow circuit includes a first conduit and a second conduit which fluidly interconnects a fluid supply with the first conduit. A pump is disposed in an intermediate portion of the second conduit. Monitoring of the pressure in the first conduit is used to identify any occlusions in that portion of the second conduit which is disposed between the pump and the fluid supply.

Abstract: A bidirectional catheter with a deflectable tip at a distal end includes a handle at a proximal end and a tubular member extending between the tip and the handle. The handle includes a first piston member slidably mounted in a handle base with proximal ends of steering wires secured in the handle. The steering wires extend through the tubular member with respective distal ends thereof secured to circumferentially spaced portions of the distal end tip. Axial displacement of the piston member in a second direction conversely urges deflection of the distal end tip in a second direction by tensioning the other wire relative to the first wire. The piston member can include another piston member slidable in the first piston member with the proximal ends of the steering wires secured in the first mentioned piston member and the handle member, respectively, and with the other piston member supporting a proximal end of the tubular member.

Abstract: A PCA device includes a fluid conduit having an upstream portion and a downstream portion, a first flow-restricting orifice in the upstream portion, a second flow-restricting orifice in the downstream portion, a pressure-responsive check valve in the downstream portion in parallel with the second flow-restricting orifice, and a bolus dose delivery mechanism including a chamber in fluid communication between the upstream portion and the downstream portion. Continuous flow is provided through the first flow-restricting orifice, the chamber, and the second flow-restrictive orifice, the continuous flow serving to fill the chamber at a controlled rate through the first flow-restrictive orifice. The bolus dose delivery mechanism is manually actuable to express the contents of the chamber through the check valve to supplement the continuous flow through the downstream portion. The bolus dose delivery mechanism includes a resilient diaphragm that forms a sealed closure for the chamber.

Abstract: An endoscopic surgical instrument for aspiration, irrigation, and blowing gas adjacent a surgical site is provided. The instrument includes a handle portion and a cannula member extending distally from the handle portion. First and second connection ports are supported by the handle and are in fluid communication with the cannula member. An insertion port is also supported by the handle portion and is preferably axially aligned with the cannula member. A blow tube is removably positioned within the cannula member via the insertion port. The first and second connection ports are adapted to communicate with a source of irrigation fluid and a vacuum source and the blow tube is adapted to be connected to a source of pressurized gas such that irrigation fluid, aspiration, and/or pressurized gas can be selectively provided via the cannula member at the surgical site.

Abstract: A process for the treatment of atrial arrhythmia by use of ablation and/or mapping procedures comprising ablating discrete ablation tracks within the left and right atrium of the heart by use of precurved left and right atrium guiding introducers, including preferably a guiding introducer system for use in the left atrium comprising an inner and an outer guiding introducer. Also disclosed are shapes for the guiding introducers and the guiding introducer system to be used for the ablation and/or mapping of the discrete tracks within the left and right atrium.

Abstract: The present invention relates to a drip chamber for an intravenous infusion set. The invention also relates to a method of making drip chambers, and further, to an intravenous infusion set including a drip chamber. The invention is provided with a drip chamber comprising a housing defining a chamber to be located in a vertical position and including an inlet at the top and an outlet at the bottom; a first hydrophilic filter covering the outlet effective, when wet, to permit the flow therethrough of a liquid and to block the flow therethrough of air; and a second hydrophilic filter covering the inlet also effective, when wet, to permit the flow therethrough of a liquid and to block the flow therethrough of air.

Abstract: There is disclosed a nasal irrigation system having an applicator or irrigating member through which a pressurized stream of irrigating fluid is passed through to the nasal passage. The applicator or irrigating member includes a tubular member, adapted for receiving a pressurized stream of fluid from a fluid source, having a bore extending therethrough. The tubular member is formed of a first portion and a second portion offset at an angle from each other. One portion of the tubular member includes an opening extending into the bore. The covering and uncovering of the opening by the user allows for the user to control the pressure of the fluid stream through the irrigating member, such that the fluid stream is directed to the nose and nasal passages when desired. A fitting is attached to an end of the tubular member for further comfort for contacting the nose. A method for using the irrigating member and the system including this irrigating member is also disclosed.

Abstract: The closed system medication administering system employs an adaptor having a hollow penetrating which can directly access a drug vial by piercing through a bung in the drug vial. A collapsible sleeve is placed around the hollow penetrating member and a membrane is disposed across the end of the sleeve to seal the hollow penetrating member when not in use. The hollow penetrating member also pierces the membrane when pushed into a drug vial. Resilient locking prongs may be provided to fixedly secure the drug vial to the adaptor or may be omitted. A reservoir bag may also be provided in a second line to fill with fluid from the primary line in order to effect reconstitution or dilution of a powdered or crystalline type drug in the drug vial. Simple manipulations of the unit consisting of the flexible bag, adaptor and drug vial allow the powdered drug to be reconstituted or diluted and subsequently dispensed.

Abstract: A portable analgesic system comprises a liquid medicine supply unit which stores a given amount of liquid medicine temporarily and then discharges the liquid medicine automatically, a first three-way connector connected to an outlet of the liquid medicine supply unit, an intermittent injection line for liquid medicine connected to one outlet of the first three-way connector, a continuous injection line for liquid medicine connected to the other outlet of the first three-way connector, and a second three-way connector for intercommunicating with outlets of the both lines.

Abstract: A steerable catheter comprises a catheter body, a control handle, and a tip section. The catheter body comprises an outer wall having proximal and distal ends and at least one lumen extending therethrough. The control handle is situated at the proximal end of the catheter body. The tip section comprises a flexible tubing having proximal and distal ends and at least one off axis lumen. The catheter also comprises a spacer at the junction of the catheter body and tip section. The spacer is made of a material more flexible than the catheter body but less flexible than the flexible tubing of the tip section. The spacer is fixedly situated between the proximal end of the tip section and the distal end of the catheter body. The catheter further comprises a compression coil and a puller wire. The compression coil extends through a lumen in the catheter body and into an off axis lumen in the tip section.

Abstract: Process for introducing a fluid into a cavity or a blood vessel of a human or animal body, particularly for gas insufflation in preparation for or during a minimally invasive surgical procedure or investigation of the body cavity or blood vessel, the fluid being conveyed from a pressurised gas store (11,12) through a fluid supply line (4) and an introduction instrument (T) of a fluid introduction system (1) into the body cavity or blood vessel and the internal pressure produced in the body cavity or blood vessel being determined from the insufflation pressure measured at a measuring point in the fluid introduction system and a correction magnitude reflecting the drop in pressure between the measuring point and the body cavity or blood vessel, wherein the internal pressure is determined substantially without interrupting the introduction of fluid from substantially continuously detected measurements of the insufflation pressure and the fluid volume introduced per unit of time (fluid flow), the gas flow yieldin

Abstract: Intravascular catheters that include a flexible catheter body, a distal housing secured to the catheter body, a work element disposed within the housing and exposed to the external environment through a side window, and a guiding structure for the work element, are disclosed. An axial path through the housing is defined by the guiding structure. Embodiments of the guiding structure include a slot or channel formed in the housing, a coaxial tube attached to the housing, a radially offset ribbon attached to the housing, or the external surface of the housing itself. The work element, such as a rotatable cutting blade in an atherectomy catheter, is coupled to the guiding structure such that the work element is retained within the housing during insertion and operation of the catheter and even when the housing is bent or distorted as a result of bends in the blood vessel.

Abstract: Devices and methods are disclosed for the percutaneous administration of a composition to a desired in vivo location. The composition comprises a biologically active substance and a pharmaceutically acceptable carrier. The pharmaceutically acceptable carrier is preferably non-solid and a polymer, which is preferably capable of being transformed into a gel, thus allowing timed-released delivery of the substance. A preferred use for this invention is to provide local delivery of biologically active substances for the prevention of restenosis following angioplasty or other blood vessel injury.

Abstract: A syringe tip device and method wherein a safety chamber is provided at the end of the hub for a slip tip, eccentric tip, or threaded tip syringe. The hub is placed on any conventional syringe in a convention manner; the safety sheath protecting the needle cannula is removed and the syringe is filled with the desired amount of medication wherein the medication is injected into a patient wherein when the process is complete, a button or lever is depressed, releasing an internal biased spring that strikes the needle cannula and bends the needle cannula within the hub chamber until the entire needle cannula is bent and destroyed within the hub chamber thus rendering the needle cannula safe from an accidental needle cannula prick.

Abstract: An automatic speed control system continually adjusts the speed of an implanted cardiac assist blood pump to an optimum level for the varying physiological needs of the patient. It does this by periodically iteratively incrementing the speed setpoint of the pump. When the system detects the imminence of a ventricular collapse at diastole, it decrements the speed setpoint by a predetermined safety margin. An alarm condition is provided if the setpoint decrease results in an insufficient blood flow rate through the pump. The flow rate and imminence of ventricular collapse are computed in real time as functions of only the pump's motor current and speed setpoint.