Patents Examined by Kevine E. Weddington
  • Positive AMPA receptor modulation to enhance brain neurotrophic factor expression
    Patent number: 6030968
    Abstract: Methods for increasing the level of neurotrophic factors and neurotrophic factor receptors in the brain of a mammal afflicted with a pathology which produces neurodegeneration without significant loss of memory or learning comprising administering to a mammal an effective amount of an allosteric upmodulator of .alpha.-amino-3-hydroxy-5-methyl-isoxazole-4-proprionic acid (AMPA) receptors.
    Type: Grant
    Filed: September 17, 1997
    Date of Patent: February 29, 2000
    Assignee: The Regents of the University of California
    Inventors: Christine M. Gall, Gary S. Lynch, Julie C. Lauterborn, Peter W. Vanderklish