Abstract: The present invention is directed to a method for the preparation of evolved microorganisms permitting the creation or modification of metabolic pathways. Strains of evolved microorganisms and evolved genes obtained by the method are also provided. The invention is also directed to the use of evolved microorganisms, genes or proteins in a biotransformation process.
Type:
Grant
Filed:
February 18, 2004
Date of Patent:
June 29, 2010
Assignee:
Metabolic Explorer
Inventors:
Michel Chateau, Benjamin Gonzalez, Isabelle Meynial-Salles, Philippe Noel Paul Soucaille, Olivier Zink