Abstract: A topical proprioceptive tube and method of use for at least activating muscle, reducing muscle fatigue, enhancing performance, or reducing a risk of knee injury. The tube includes a flexible sleeve having at least: a hamstring buttress, a knee buttress, or both, wherein the hamstring buttress and the knee buttress are configured to be coupled to the interior of the flexible sleeve such that the hamstring buttress applies pressure to at least a portion of one of the subject's hamstring muscles and the knee buttress applies pressure to at least a portion of the subject's Vastus Medialis Obliquus (VMO) when worn by the subject to provide a desired effect.