Abstract: The invention provides novel mixtures of quaternary ammonium salts having plant growth-regulating properties. The salts, as well as other active ingredients used to regulate plant growth, are dissolved in solvents having either formula II(a) or II(b), as depicted below:
or
wherein
“R” is Hydrogen or a C1-C18 alkyl,
“n” is 0, 1,2 or 3,
“A” is a C1-C6 alkene or a C1-C6 oxyalkylene,
“m” is 1, 2, 3, 4 or 5, and
“B” is a straight-chain or branched C2-C8 alkylene.
Type:
Grant
Filed:
October 20, 1998
Date of Patent:
April 23, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Reiner Kober, Karl-Heinrich Schneider, Hans Ziegler, Mary Elizabeth Callan, Charles W. Finch, Reinhold Stadler, Peter Hofmeister, Wilhelm Rademacher, Elmar Kibler, Reimer Göttsche
Abstract: There is described a process for the-preparation of cosmetic products, in particular cosmetic products. The process comprises the preparation of 5-99.999% by weight of a powder phase, the preparation of 0.0001-95% by weight of an oily, waxy and/or polymeric lipid phase and the mixture of the two phases through the use of CO2 as a solvent, in supercritical condition and non.
Abstract: Compositions, for example cosmetic or dermatological compositions, which are in solid form, and which comprise at least one oil, at least one compound of formula I, and less than about 5% by weight of wax relative to the total weight of the composition. The compositions can be in the form of a translucent or even transparent anhydrous stick. They can be, for example, optionally colored “transfer-resistant” or “non-migrating” compositions. Cosmetic treatment processes for a support chosen from facial and body skin, mucous membranes and keratin fibers, comprising applying these compositions to the support.
Abstract: A sustained release ranolazine formulation contains an intimate mixture of ranolazine and a partially neutralized pH-dependent binder to form a film that is mostly insoluble in aqueous media below pH 4.5 and soluble in aqueous media above pH 4.5. The formulation is suitable for twice daily administration of ranolazine and is useful for controlling the rate of dissolution of ranolazine, and to maintain human plasma ranolazine levels at between 550 and 7500 ng base/mL.
Type:
Grant
Filed:
March 29, 2000
Date of Patent:
April 9, 2002
Assignees:
CV Therapeutics, Inc., Syntex (USA) Inc.
Inventors:
Andrew A. Wolff, Fiona Baker, John Langridge
Abstract: A cosmetic or pharmaceutical composition used for blocking the penetration of ultraviolet radiation, the composition containing nanoscale organic UV filters having a mean diameter of from 10 to 300 nm.
Type:
Grant
Filed:
December 8, 1999
Date of Patent:
April 9, 2002
Assignee:
Cognis Deutschland GmbH
Inventors:
Christian Kropf, Hans Dolhaine, Thomas Foerster, Bernd Fabry
Abstract: The present invention discloses a method for topical application of an enzyme, wherein the enzyme becomes incorporated in a peelable film, for instance a polyvinyl alcohol film, after its application. In this way, the release of enzyme-containing dust particles from the site of application is prevented.
Abstract: The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.
Type:
Grant
Filed:
March 23, 1999
Date of Patent:
April 2, 2002
Assignee:
ALZA Corporation
Inventors:
David E. Edgren, Patrick S.-L. Wong, Francisco Jao, Yolanda M. Puga
Abstract: Antiperspirant compositions herein comprise an antiperspirant active, together with a carrier and a structurant for the carrier which comprises an organic wax having a melting point of from 40 to 90° C. of which at least 60% of the weight of the wax is provided by at least one aliphatic ester satisfying the formula:
CH3—(CH2)n—CO—(CH2)m—CH3
in which n is from 9 to 39 and m is from 0 to 35 to form a solid or a soft solid. The compositions can be anhydrous, in the form of a suspension of antiperspirant active, or can comprise aqueous emulsions.
The formulations structured by the selected waxes provide lower visible deposits on topical application compared with conventional wax-structured formulations and the waxes are effective at structuring/thickening at a proportion below that in conventional wax-structured formulations.
Type:
Grant
Filed:
June 2, 2000
Date of Patent:
March 26, 2002
Assignee:
Unilever Home & Personal Care USA, division of Conopco,
Inc.
Inventors:
Bruce Steven Emslie, Laura Dimitrova Stoimenof, Graham Andrew Turner
Abstract: An emulsion comprising an aqueous phase and an oily phase and additionally comprising a hydrophilic thickening compound and a lipophilic thickening copolymer. A cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, such an emulsion. The use of such a combination makes it possible to stabilize an emulsion, in particular an oil-in-water emulsion and more particularly an emulsion not comprising a surfactant.
Abstract: The invention concerns a cosmetic or dermatological composition designed for for forming a film on a keratin substrate, in cross-linked hybrid material. Said composition is of the sol/gel type and is obtained by mixing: (a) at least an organometallic compound; (b) at least a functionalised organic polymer or said polymer precursor, or at least a functionalised silicone polymer or said polymer precursor, the precursor being different from (a); (c) a sufficient amount of water for hydrolysing the organometallic compound: and (d) optionally at least an alcohol; said film being non-reversible.
Type:
Grant
Filed:
December 3, 1999
Date of Patent:
March 5, 2002
Assignee:
L'Oreal
Inventors:
Jean Mondet, Francis Xavier Quinn, Clément Sanchez
Abstract: The invention relates to a non-aqueous, emulsifiable concentrate (EC) formulation for herbicidal crop protection active compounds which consists essentially of
(a) 25 to 150 g/L of at least one fluorinated herbicidal compound,
(b) 400 to 900 g/L of one or more herbicidal alkyl phenoxyalkanoates,
(c) 10 to 100 g/L of at least one non-ionic surfactant,
(d) 10 to 100 g/L of at least one benzene sulfonate,
(e) 50 to 600 g/L of one or more solvent selected from the group consisting of aliphatic or aromatic hydrocarbons, methylated plant oils and water-miscible polar aprotic organic solvents, and
(f) optionally, up to 5 g/L of at least one defoamer,
and to the use of such a emulsifiable concentrate as a herbicide.
Abstract: A skin cleaning, bacterial control, foam solution is provided, which enables a user to wash without requiring pre-wetting with water; this is followed by rinsing off the foam. The foam solution product is produced by mixing foaming and cleaning ingredients, active bacterial control ingredients, and water with a gas such as air, CO2, nitrogen, propellant, etc., to make the foam. The foam solution and method enables a improved coverage, better penetration, less time, and the least amount of active ingredients for controlling microorganisms when used for personal care washing. The lubricity of the water enables an easier wash, without the prior application of water; the wash is then followed by rinsing. The method for producing a foam surfactant suitable for a combined bovine teat dip and teat wash comprises air pressurization of a surfactant solution containing a germicide, disinfectant, biocide, etc.
Abstract: The invention relates to a molded antimicrobial article including an infiltrated antimicrobial agent which forms independent phases of 0.01 &mgr;m or more in short diameter in the molded article. The antimicrobial agent is a pyridine based antimicrobial agent with a molecular weight of 200 to 700 and an inorganic property/organic property value of 0.3 to 1, and 50% or more of the antimicrobial agent is infiltrated in a depth range of 0.5 &mgr;m or more from the surface of the molded article, or that 30% or more of the antimicrobial agent is infiltrated in a depth range of 2 &mgr;m or more from the surface of the molded article. The molded antimicrobial article of the invention can be obtained by immersing a fibrous product in a dyeing liquid containing the pyridine based antimicrobial agent, and treating simultaneously with dye under pressurization, or by applying a liquid containing a pyridine based antimicrobial agent to a fibrous product by padding or spraying, and heat-treating it at 160 to 200° C.
Abstract: The invention relates to novel detergent and conditioning compositions having at least one anionic surfactant, at least one amphoteric surfactant, at least one oil of polyolefin type, at least one cationic polymer and at least one water-soluble salt or alcohol; wherein the anionic surfactant/amphoteric surfactant weight ratio being less than or equal to 3; and to application of the compositions to clean and care for the hair or the skin.
Abstract: Pharmaceutical compositions comprising electrostatic and steric-stabilized sub-micron and micron-size stable microparticles of water-insoluble or poorly soluble drugs or other industrially useful insoluble compounds having diameters of about 0.05 to about 10 microns are described. The particles have phospholipid coated surfaces and are stabilized with a combination of charged surface modifier and block copolymer. The diameter of the particles is greater than about 50% but less than 100% of the diameter of particles comprising the poorly soluble drug and the phospholipid coated surfaces prepared by otherwise identical means in the absence of the combination of charged surface modifier and block copolymer. The charged surface modifier provides electrostatic stabilization and the block copolymer provides steric stabilization that minimize particle size growth caused by Ostwald ripening and particle aggregation and provides for small particle formation.
Abstract: The present invention is drawn to a device for the transdermal administration of dextromethorphan, (+)-3-methoxy-17-methyl-9a,13a,14a-morphanin, and salts, prodrugs and metabolites thereof, together with a pharmaceutically acceptable carrier, to a human being or animal in need thereof, to achieve an antitussive effect. The present invention is further drawn to a method of achieving an antitussive effect in a human being or animal which comprises transdermally administering dextromethorphan, (+)-3-methoxy-17-methyl-9a,13a,14a-morphanin, and salts, prodrugs and metabolites thereof, together with a pharmaceutically acceptable carrier.
Type:
Grant
Filed:
October 23, 1998
Date of Patent:
January 1, 2002
Assignee:
Pharmacia & Upjohn AB
Inventors:
Ulla Hoeck, Bo Kreilgaard, Helle Kristensen
Abstract: The invention relates to the use of at least one compound of formula:
in which R1 and R′1 are C1-C18 alkyl radicals which are optionally substituted by one or more halogens or hydroxyls and/or are interrupted by one or more heteroatoms, and R2 to R5 and R′2 to R′5 are hydrogen or halogen atoms, hydroxyl radicals or C1-C6 alkyl, alkyloxy, acyl or acyloxy radicals, in a cosmetic composition, in particular a make-up composition, in order to confer on it antimicrobial properties and properties of lengthy hold over time and/or of non-migration and/or of freedom from transfer and/or of non-formation of streaks.
The invention also relates to a cosmetic composition, in particular a make-up composition and especially an eyeshadow, comprising such a compound in a silicone binder.
Abstract: Use of a specific particulate phase in a cosmetic composition, in particular a make-up composition, and cosmetic composition comprising such a particulate phase. Use of a particulate phase comprising particles with mean dimensions ranging from 5 to 100 microns and preferably from 20 to 50 microns and comprising at least two consecutive faces, the normals of which at the median point form, between one another, an angle at least equal to 90°, in a cosmetic composition, in particular a make-up composition, for the purpose of limiting, decreasing or eliminating the blemishes of keratinous substances and/or of modifying the perception of the volume of some regions of the said substances.
Cosmetic composition, in particular in make-up composition, such as a foundation, comprising such a particulate phase.
Abstract: A composition containing vernix to provide therapeutic treatment in a human, and a method for using the composition, are disclosed. The composition may contain a natural or synthetic medicament, or may be manipulated to regulate transport properties. The medicament may be, for example, a protectant against ultraviolet radiation or an antioxidant. Various compositions and uses of vernix, both natural and synthetic, are disclosed. The compositions may be used in embodiments such as skin protection, wound healing, and restoration of epidermal barrier function.
Type:
Grant
Filed:
November 22, 1999
Date of Patent:
December 25, 2001
Assignee:
Children's Hospital Medical Center
Inventors:
Steven B. Hoath, William L. Pickens, Martha O. Visscher
Abstract: In order to provide a selective antibacterial composition which distinguishes a harmful Staphylococcus aureus that exists on diseased skin from a harmless Staphylococcus epidermidis that exists on a healthy skin, which shows sufficient ability to treat and prevent skin disease by limiting its antibacterial effect to the harmful S.aureus without affecting to the growth of the harmless S.epidermidis, and which is a external preparation for the treatment of atopic dermatitis especially, the selective antibacterial composition of the present invention contains a farnesol and/or a xylitol.