Patents Examined by Konstantha Katcheves
  • Increase of nodule number and nitrogen fixation in leguminosae
    Patent number: 6492176
    Abstract: The present invention relates to a new mutant Rhizobium etli CNPAF 512 strain, having an inactivated raiI gene. Inactivation of the raiI gene leads to increased nodule number in beans upon inoculation thereof with the mutant strain. Based on this specific strain other strains can be mutated in the similar gene(s) in order to enable nodule increase and nitrogen fixation in other Leguminosae species.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: December 10, 2002
    Assignee: K.U. Leuven Research & Development
    Inventors: Viola Rosemeyer, Jozef Vanderleyden
  • Method of combinatorial protein synthesis based on ribosomal frameshifting
    Patent number: 6440700
    Abstract: Disclosed are materials and methods for practicing combinatorial protein synthesis based on ribosomal frameshifting. The genes, encoding the proteins to be synthesized, are constructed by assembly of several double-stranded DNA fragments and are cloned into bacteria. The genes include interspersed frameshifting sequences. Proteins are made in the cell by translating nucleotide sequences in a combinatorial mode. The invention can be used for the selection of new, modified or improved proteins.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: August 27, 2002
    Inventor: Wlodek Mandecki