Patents Examined by Konstantina M. Katcheves
  • Method for isolating DNA from biological materials
    Patent number: 6992182
    Abstract: The invention relates to a method for the stabilization, purification or/and isolation of nucleic acids from biological materials, in particular stool samples which may contain contaminations and interfering substances. Furthermore, a reagent kit suitable for carrying out the method of the invention is described.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: January 31, 2006
    Assignee: Qiagen GmbH
    Inventors: Oliver Müller, Markus Sprenger-Haussels, Helge Bastian, Stefanie Vollert
  • Methods and compositions for nucleic acid delivery
    Patent number: 6992070
    Abstract: The present provides methods and compositions that enable effective delivery of nucleic acids to desired cells, including to a solid organ such as a mammalian heart. The methods and compositions enable effective gene transfer and subsequent expression to a majority of cells throughout a solid organ such as the heart. Methods and compositions of the invention preferably provide enhanced vascular permeability that enables increased gene transfer to targeted cells, but without significant degradation or injury to endothelial cell layers.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: January 31, 2006
    Assignee: The Johns Hopkins University
    Inventors: J. Kevin Donahue, Eduardo Marban, Koichi Nagata, John H. Lawrence