Abstract: A continuous segment of chromosomal DNA from E. coli O157:H7, isolated on plasmid pSC(overlap) (ATCC No. 69648), encodes an adhesin (SEQ ID NO:4) that mediates bacterial colonization of bovine intestines.
Type:
Grant
Filed:
March 26, 1997
Date of Patent:
August 25, 1998
Assignees:
Children's Hospital and Medical Center, University of Washington, Washington State University Research Foundation
Inventors:
Phillip I. Tarr, Sima S. Bilge, Thomas E. Besser, James C. Vary, Jr.
Abstract: Biologically active variant tissue plasminogen activators are disclosed. The disclosure focuses on position 276 variants that exhibit enhanced fibrin specificity.
Type:
Grant
Filed:
July 14, 1994
Date of Patent:
May 26, 1998
Assignee:
Genentech, Inc.
Inventors:
Herbert L. Heyneker, Gordon A. Vehar, Nicholas F. Paoni, William F. Bennett
Abstract: The present invention relates to improved plasminogen activators (improved t-PA) which have a prolonged biological half life, an increased stability to heat and acids and can be expected to be effective as inhibiting inflammation around the site in which thrombus is formed.
Abstract: This invention provides a family of insecticidally effective proteins and particular members of that family which may be isolated from the venom of the spider Filistata hibernalis, DNA encoding such proteins, insecticidal compositions of these proteins or the DNA encoding them, and methods for controlling invertebrate pests. Recombinant expression vectors and host cells and methods for producing insecticidally effective peptides are also provided.
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
December 9, 1997
Assignees:
FMC Corporation, NPS Pharmaceuticals, Inc.
Inventors:
John Randolph Hunter Jackson, Karen Joanne Krapcho, Janice Helen Johnson, Robert Marden Kral, Jr.
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