Patents Examined by Krisanne Thornton
  • Patent number: 6537494
    Abstract: There is disclosed a sterilizing fog, characterized by droplet size range, vapor density range, sterilant concentration range and sterilant concentration within the droplets. Specifically, there is disclosed a fog achieved by an apparatus combining pressure, temperature and acoustics to form a super-charged ozoneated water and an apparatus that creates small micro droplets which form a highly concentrated sterilizing fog. Specific sterilants used are ozone, chlorine and chlorous acid generating compositions such as sodium hypochlorite, or combinations thereof.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: March 25, 2003
    Assignee: Holographic Engineering LLC
    Inventor: Todd Garlick
  • Patent number: 6534004
    Abstract: A method that allows for dry storage of bioprosthetic devices comprising a tissue component is provided. The method comprises the steps of providing a device comprising a chemically cross-linked animal tissue component; treating the tissue component with an aqueous solution comprising a biocompatible, water soluble, organic molecule comprising a plurality of carbon atoms and a plurality of hydroxyl groups for a time sufficient to allow equilibration between the fluids in the interstices of the tissue component and the aqueous solution; and then sterilizing the treated tissue component using a sterilizing gas or ionizing radiation. The present invention also relates to an implantable tissue component that can be stored dry. The tissue component is chemically-fixed and comprises within the interstices thereof a dimensional stabilizer selected from the group consisting of a polyhydric alcohol and derivatives thereof, a water soluble carbohydrate, and a water soluble gum.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: March 18, 2003
    Assignee: The Cleveland Clinic Foundation
    Inventors: Ji-Feng Chen, Kent Wika
  • Patent number: 6534000
    Abstract: A sterilization cassette and a sterilization method for sterilizing, storing, and dispensing dental instruments. The sterilization cassette includes a mounting bar and a locking bar for dental pliers of various types, a removable instrument tray, and a case with a front side which opens and hinges in two places, allowing the cassette to be arranged in horizontal and vertical configurations.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: March 18, 2003
    Assignee: Steri Source, Inc.
    Inventors: Dennis J. Michaelson, Jeffrey W. Mix
  • Patent number: 6528016
    Abstract: A method is provided for rapidly determining whether a load of equipment to be sterilized in a sterilization chamber absorbs, adsorbs, condenses, or decomposes significant amounts of germicide vapor or gas, such as hydrogen peroxide. The initial slope of the curve of a plot of ln(c/co) versus time is determined, where c is the concentration of hydrogen peroxide and co is the maximum concentration of hydrogen peroxide. The initial slope is determined in the first 100 seconds after the maximum in the concentration of hydrogen peroxide. If the initial slope is approximately 0.016 sec−1 or less, the load is acceptable. If the initial slope is significantly steeper than 0.016 sec−1, the load absorbs, adsorbs, condenses, or decomposes significant amounts of hydrogen peroxide. If the slope of the curve is steep, the system can abort the sterilization run before significant amounts of hydrogen peroxide have been absorbed, adsorbed, or condensed.
    Type: Grant
    Filed: June 27, 2000
    Date of Patent: March 4, 2003
    Assignee: Ethicon, Inc.
    Inventors: James P. Kohler, Nancy S. Chu
  • Patent number: 6524535
    Abstract: An adsorptive decomposition deodorizing element comprising of a heating unit having an electrical heating unit inserted between laminated mica plates and a deodorizing unit located on the peripheral surface of said heating unit which can be heated very quickly, gives little offensive odor even in the step of regeneration by heating, and has a light weight and an excellent processability.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: February 25, 2003
    Assignee: Nikki-Universal Co., Ltd.
    Inventors: Yoshiki Nakano, Eiki Iida, Ryouji Aikawa
  • Patent number: 6524537
    Abstract: A fragrance emitter used with internet is disclosed. The fragrance emitter is able to emit various kinds of fragrance stored in vessels according to the command sent by a frequency detector which is used to search for the existence of a specific frequency specially used by a specific web site. Therefore, when the existence of a specific frequency matches with a predetermined frequency, the electromagnetic valve is able to activate the movement of a valve mounted on a fragrance vessel in an air tight manner, such that the fragrance is ventilated and mix with the air by a fan.
    Type: Grant
    Filed: March 7, 2000
    Date of Patent: February 25, 2003
    Inventor: Chum Lee
  • Patent number: 6521178
    Abstract: A method by which medical equipment, such as surgical scalpels, can be sanitized using a detergent or treating composition containing a surfactant and a solvent such as water is disclosed. The method involves taking the used medical equipment and contacting it with the treating composition, and subjecting both the equipment and composition to microwaves. The composition foams during microwaving and/or immerses the equipment such that microwave arcing is avoided, and such that the medical equipment is sanitized.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: February 18, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Alan Scott Goldstein, Howard David Hutton
  • Patent number: 6521180
    Abstract: A method of sterilizing an instrument having an exterior and a proximal end in a chamber of a sterilizing apparatus, the method including the following steps: washing the instrument with a rinse fluid; removing bio-burden from the instrument with a bio-burden removing fluid; stabilizing a sterilization temperature at which sterilization of the instrument occurs; sterilizing the instrument; a first rinsing of the instrument with the rinse fluid; and a first drying of the instrument. The sterilizing step includes: applying to the instrument a first application of a sterilizing fluid at a first predetermined flow rate and applying to the instrument a second application of the sterilizing fluid at a second predetermined flow rate. The first application includes a first predetermined sequence of pulses of the sterilizing fluid and a driving fluid. The second application includes a plurality of pulses of the sterilizing fluid.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: February 18, 2003
    Assignee: Sermed Industries, Inc.
    Inventors: Roberto M. Sergio, Winfield Wood, Jr.
  • Patent number: 6514467
    Abstract: An air-freshener for a vehicle, in particular a motorcar, provided with a housing into which a container for a volatile liquid or a liquid containing one or more volatile components can be inserted, in the opening of which container a wick extending into the housing is fitted. There are further present a covering cap which, when the container with wick has been inserted into the housing, is movable up and down over the wick, and control means for setting the position of the covering cap.
    Type: Grant
    Filed: February 23, 2000
    Date of Patent: February 4, 2003
    Assignee: Sara Lee/DE N.V.
    Inventors: Dirk Jan Bulsink, Johannes Arnoldus van Voorden, Johannes Antonius Gerardus Wilhelmus Zigmans
  • Patent number: 6503458
    Abstract: A device for purifying air within a room. The device includes a housing having a plurality of air inlet ports and a plurality of air outlet ports. An ultraviolet ray generator is positioned within the housing along with a fan for drawing air into the housing through the air inlet ports. A passageway leading from the air inlet ports and encircling the ultraviolet ray generator to the air outlet ports provides a path for air drawn into the housing. The ultraviolet rays produced by the generator kill bacteria, germs and viruses in the air passing thereby through the passageway and the passageway maximizes a distance traveled by the air through the housing and thereby maximizing exposure of the air to the ultraviolet rays. The device also generates ozone for neutralizing undesirable odors, such as stale tobacco smoke and mildew in the air drawn into the housing.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: January 7, 2003
    Inventor: William D Ogle
  • Patent number: 6495096
    Abstract: A deodorant, for substances containing hydrogen sulfide or mercaptans, which includes a combination of a peroxide and a nitrate ion, a combination of a peroxide, a nitrate ion and a metal salt, or a combination of a chelating agent and one of the above combinations, and a process for deodorization comprising treating a substance for treatment, containing hydrogen sulfide or mercaptans, with the above deodorant. Smell caused by hydrogen sulfide or mercaptans is effectively removed by the deodorant. Smell from waste water, sludge, and water discharged from washing apparatuses can be efficiently removed with use of the deodorant in a small amount in accordance with this process.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: December 17, 2002
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Takayoshi Hamaguchi, Kazuyuki Minato, Toshimi Matsumoto, Tadashi Shimomura
  • Patent number: 6488889
    Abstract: A process is described for evacuating a reactor, in which at least one object is sterilized by means of Low pressure plasma. The reactor must be evacuated from atmospheric pressure to plasma discharge pressure. At least two separate, successive evacuation stages are hereby provided. In the first. evacuating stage and a possible further evacuation stage, the reactor is brought down step by step to a reduced intermediary pressure. In the last evacuation stage the reactor is evacuated to the plasma discharge pressure. For each evacuation stage it is advantageous to provide a separate vacuum chamber, to each of which the reactor is corrected. This brings with it the advantage that the entire amount of gas does not need to be transported through one single pump or a single set of pumps.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: December 3, 2002
    Assignee: Rudiger Haaga GmbH
    Inventors: Werner Stahlecker, Robert Frost
  • Patent number: 6485684
    Abstract: A fluid disinfection or sterilization system includes spray nozzles (26) for spraying an anti-microbial fluid on the exterior of an endoscope (14) supported in a microbial decontamination chamber (10a, 10b). The endoscope includes interior lumens which are microbially decontaminated by flowing anti-microbial fluid from outlets (28) through the lumens. A port (36) is connected with a leak detector. In order to ensure that the proper leak detector and anti-microbial fluid ports of the disinfection or sterilization system are interconnected with the proper lumen ports of the endoscope, a tethered connection assembly (50) is provided. The tethered interconnection assembly includes fittings (60, 62, 64) which are uniquely configured for interconnection with an appropriate one of a high pressure port, a low pressure port, and the leak detector port. Fittings at the other end of the tube assemblies (56) are configured for interconnection with appropriate corresponding ports of the endoscope.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: November 26, 2002
    Assignee: Steris Inc.
    Inventors: Tara Denise Mapson, Yury Keselman, David Jesurun, Victor M. Selig, Joseph Tvergyak, Richard A. Schieman, Bruce L. Vavra, Joseph T. Sestak
  • Patent number: 6482356
    Abstract: A pump is supported on a housing and has an inlet port coupled to a lubricant supply and an outlet port coupled to a tube outlet opening for delivering a predetermined amount of the lubricant during an activated cycle of the pump. An actuator, when triggered, operates in an actuated state for a predetermined duration during which time the pump is activated for one cycle and delivers a predetermined amount of the lubricant to the tube outlet opening. A switch is independently selectable for triggering the actuator to activate only the active cycle of the pump. The actuator may be a spring-biased solenoid or a timer circuit with a relay. The pump may be a piston-diaphragm type or any one of various motor driven types. The pump is activated for about 1 second, without also activating a cleaning cycle or a purging cycle and delivers ⅛ to ½ cc of a lubricant comprising about 90% by volume of a pharmaceutical grade mineral oil and about 10% by volume of NNL-690.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: November 19, 2002
    Inventor: Kenneth R. Brown
  • Patent number: 6482358
    Abstract: A sequential delivery assembly (30) sequentially releases three different treatment materials into a fluid flow path (24) to form a treatment fluid with a composition which varies throughout a cleaning and microbial decontamination cycle. A chamber (12) receives items to be cleaned and decontaminated. A pump (22) pumps the treatment fluid from the sequential delivery assembly along a fluid flow line (24) to nozzles (16, 18) disposed within the chamber. The nozzles spray the treatment fluid over the items to be cleaned and decontaminated. The delivery assembly includes a well (34) for receiving a three compartment cup (44). The cup contains a first compartment (70) which includes a cleaning material (76), such as a detergent. A second compartment (72) contains pre-treatment materials (78), such as buffers and corrosion inhibitors, which prepare the system for receiving a microbial decontaminant (80), such as a concentrated solution of peracetic acid, contained in the third compartment (74).
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: November 19, 2002
    Assignee: Steris Inc.
    Inventors: Daniel N. Kelsch, Jude A. Kral, Joseph Tvcrgyak, Bernard J. Moss, James C. Hlebovy, Arthur T. Nagare, Jeffery R. Horacek
  • Patent number: 6471914
    Abstract: A process for sterilization of a liquid in a continuous system comprising a series of steps. First the liquid is continuously pumped into a pressurized system. Second, the pressure on the liquid is increased in a first pressurization stage. Next, the liquid is increased in pressure in a second pressurization stage. Fourth, the liquid is held at an elevated pressure for a predetermined period of time to kill off microorganisms within the liquid. The liquid is then rapidly depressurized to fracture microorganisms with the liquid. The apparatus for producing this process includes a continuous liquid treatment system with a pump, a first stage intensifier, a surge drum, a second stage intensifier, a pressure receiver and a pressure reducer. A particulate treatment system may also be included which comprises a pressure receiver, an intensifier, and a recoverer for blending a particulate component with the liquid component.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: October 29, 2002
    Assignee: The Coca-Cola Company
    Inventors: Gerald M. Platz, N. Wayne Walkup, Howard L. Grimmett
  • Patent number: 6468482
    Abstract: A flash sterilization container (10) comprises a pan (12) forming the bottom of the container holding a tray (14), with a cover (16) forming the top of the container, and a filter element (20). Items to be sterilized are placed on the tray (14) and the cover (16) is attached and sealed to the pan (12). The sealed container is then placed in an autoclave or other source of pressurized steam. Items which require “stat” sterilization can be placed in a basket (80) with a plurality of vent holes (83) which further limits the amount, and therefore the whole mass, of the instruments placed into the container for sterilization and significantly decreases the time required for sterilization. The filter (20) allows the steam to enter the interior of the container and sterilize any items contained therein.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: October 22, 2002
    Assignee: Case Medical, Inc.
    Inventors: Marcia A. Frieze, Allan S. Frieze, Kate Kislevitz
  • Patent number: 6461568
    Abstract: Methods and apparatus for sterilizing small objects. A small object is inserted into a chamber formed in the sterilizer. A portion of the small object mates with a lockout device to disable the lockout device. After the lockout device is disabled, the sterilizer produces at least one flash of high intensity ultraviolet light produced by an ultraviolet light source. The ultraviolet light flash kills microorganisms on the surface of the small object. The chamber of the sterilizer may be lined with a reflective coating to disperse the ultraviolet light around the chamber so that most, if not all, of the small object within the sterilizer is exposed to the ultraviolet light.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: October 8, 2002
    Assignee: UV-Solutions, LLC
    Inventor: Richard A. Eckhardt
  • Patent number: 6461567
    Abstract: A device comprising a light source, a sample holder and a temperature control chamber. The sample holder supports the vessels in a fixed relationship relative to the light source. The temperature control chamber surrounds the sample holder and vessels, so that a temperature control fluid may be passed around the sample vessels effectively maintaining the temperature of the sample vessels within a desired temperature range.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: October 8, 2002
    Assignee: Cerus Corporation
    Inventors: David Paul Hearst, George D. Cimino, John Eugene Hearst, Stephen T. Isaacs
  • Patent number: RE37932
    Abstract: A supermicrocellular foamed material and a method for producing such material, the material to be foamed such as a polymerplastic material, having a supercritical fluid, such as carbon dioxide in its supercritical state, introduced into the material to form a foamed fluid/material system having a plurality of cells distributed substantially throughout the material. Cell densities lying in a range from about 109 to about 1015 per cubic centimeter of the material can be achieved with the average cell sizes being at least less than 2.0 microns and preferably in a range from about 0.1 micron to about 1.0 micron.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: December 10, 2002
    Assignee: Massachusetts Institute of Technology
    Inventors: Daniel F. Baldwin, Nam P. Suh, Chul B. Park, Sung W. Cha