Patents Examined by Kristin Ann Vajda
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Patent number: 10098837Abstract: Aerosol formulations comprising glycopyrronium bromide, formoterol or a salt thereof, and beclometasone dipropionate are useful for the prevention or treatment of moderate/severe chronic obstructive pulmonary disease.Type: GrantFiled: July 28, 2017Date of Patent: October 16, 2018Assignee: CHIESI FARMACEUTICI S.p.A.Inventors: Mario Scuri, Pierfrancesco Coli, Giuseppe Delmonte
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Patent number: 10085951Abstract: The invention provides novel curcuminoid formulations which have improved aqueous solubility and bioavailability when compared to known curcuminoid dosage forms. Formulations of the invention exhibit an enhanced intestinal absorption of curcuminoids, a slower curcuminoid metabolism and a reduced rate of systemic curcuminoid elimination. Additionally, upon administration in vivo, the formulations described and claimed herein produce a high, sustained level of the curcuminoid metabolite tetrahydrocurcumin. For example, at about eight to about ten hours after oral administration to a human, tetrahydrocurcumin plasma levels of between about 50 ng/mL to about 175 ng/mL are detectable, even when that metabolite is absent from the administered formulation. Novel processes for making curcuminoid formulations which have improved aqueous solubility and oral bioavailability, and methods of treating a wide variety of inflammatory, immune and neurogenerative disorders and cancers, are also provided.Type: GrantFiled: December 8, 2015Date of Patent: October 2, 2018Assignee: DESIGNS FOR HEALTH, INC.Inventors: Sarah M. Gannon, Jose A. Llobrera
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Patent number: 10080803Abstract: Oil-in-water emulsions are prepared using phospholipids purified from krill.Type: GrantFiled: April 24, 2015Date of Patent: September 25, 2018Assignee: Aker BioMarine Antartic ASInventor: Stefan Hupfeld
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Patent number: 10071044Abstract: A thickened composition that does not lose viscosity even in the presence of an organic acid. A thickened composition, including a polyhydric alcohol, water, an organic acid, and a lipid peptide-type compound containing at least one of a compound of Formula (1) to Formula (3) below and a pharmaceutically usable salt of compound of Formula (1) to Formula (3), where R1 is a C9-23 aliphatic group, R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a C1-2 branched chain, R3 is a —(CH2)n—X group, n is a number of 1 to 4, X is an amino group, guanidino group, —CONH2 group, a 5-membered ring group optionally containing 1 to 3 nitrogen atom(s), a 6-membered ring group optionally containing 1 to 3 nitrogen atom(s), or a condensed heterocycle group that contains a 5-membered ring and a 6-membered ring optionally containing 1 to 3 nitrogen atom(s).Type: GrantFiled: May 14, 2015Date of Patent: September 11, 2018Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.Inventor: Takayuki Imoto
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Patent number: 10071064Abstract: Methods and formulations for batch-mixing flavonoid tinctures and infusing the flavonoid batch-mixed tincture into a food, beverage, cosmetic or drug products with minimal or no effect on the alcohol by volume of the product, and to precisely deliver the desired mixture concentration of the flavonoids, is provided. A batch-mixed flavonoid tincture includes an amount of at least two individual flavonoid tinctures, each flavonoid tincture being a mixture of at least a flavonoid and a solvent. The batch-mixed tincture is added to various food and beverages, or alternatively directly administered to a human or animal, to make a bioavailable amount of flavonoids to be absorbed and metabolized by the body providing demonstrated health benefits.Type: GrantFiled: September 18, 2017Date of Patent: September 11, 2018Assignee: Heart Healthy Spirits, LLCInventors: Kim A. Popejoy, Jeffrey J. Keaffaber
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Patent number: 10065965Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT) and leishmaniasis, particularly visceral leishmaniasis (VL).Type: GrantFiled: May 26, 2016Date of Patent: September 4, 2018Assignees: GlaxoSmithKline Intellectual Property Development Limited, The University of DundeeInventors: Stephen Brand, Elisabet Viayna Gaza, Ian Gilbert, Eun Jung Ko, Maria Marco Martin, Timothy James Miles, Lars Henrik Sandberg, Michael George Thomas
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Patent number: 10058565Abstract: This invention discloses a process for creating an amino acid-based vitamin and mineral dietary supplement and muscle builder having therapeutic activities such as an antioxidant and a metabolic regulator, a regulator of possible cell dysfunctions, an adjuvant of human vitality and well-being and reduction of pain caused by different diseases wherein 2-aminoetanol dihydrogen phosphate is synthesized from phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid reacted as monoethanolamine and/or diethanolamine and/or triethanolamine. These are reacted under optimal temperature conditions (?10 to +35° C.) at the specific molar ratios for each reagent used.Type: GrantFiled: August 18, 2016Date of Patent: August 28, 2018Inventors: Marcos Vinicius De Almeida, Renato Meneguello
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Patent number: 10053429Abstract: The present invention provides compounds of the Formula below: [Formula should be inserted here] Where A, X, R. and R2-R3 are as described herein; methods of treating patients for hypertriglyceridemia and cardiovascular disease including dyslipidemia and atherosclerosis, and processes for preparing the compounds.Type: GrantFiled: May 19, 2016Date of Patent: August 21, 2018Assignee: Eli Lilly and CompanyInventors: Ana Maria Escribano, Maria Rosario Gonzalez, Celia Lafuente Blanco, Maria Dolores Martin-Ortega Finger, Michael R Wiley