Patents Examined by Kristin K. Larson
  • Patent number: 5505940
    Abstract: The present invention provides a process of formulating a pest control agent into a sprayable gluten-based formulation. A gluten-based formulation for use in pest control is also provided. The present invention also provides a process of decreasing the population of a pest of a living organism comprising formulating a pest control agent into a sprayable gluten-based formulation and delivering the formulation to the external surface of the living organism.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: April 9, 1996
    Assignees: The United States of America as represented by the Secretary of Agriculture, Biotechnology Research & Development Corporation
    Inventors: Michael McGuire, Baruch Shasha
  • Patent number: 5455171
    Abstract: A microorganism exhibiting excellent antibiotic and sterilizing properties for the preparation of medicines and the like, obtained by fusion of cells of two different fungal species. A Ganoderma and a Grifola, each exhibiting little or no antibiotic activity, are isolated and hybridized, and milled to produce a fused cell body. The cell body is black-brown, and has been deposited as deposit No. 3131 (FERM BP-3131).
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: October 3, 1995
    Inventors: Kazuo Yanai, Takeshi Yanai, Isao Yanai
  • Patent number: 5443829
    Abstract: Disclosed herein are modified saponins or fractions thereof obtainable by modification of a crude Quillaja saponaria extract or by modification of purified saponins obtainable from a crude Quillaja saponaria extract useful in pharmaceutical compositions for enhancing the transport of pharmacologically active substances across mucous membranes of an animal. Also disclosed are modified saponins having reduced irritability wherein the aldehyde group is reduced and the fatty acid moiety may be removed by hydrolysis. Also disclosed are pharmaceutical compositions comprising the modified saponins of the invention.
    Type: Grant
    Filed: September 24, 1993
    Date of Patent: August 22, 1995
    Assignee: Cambridge Biotech Corporation
    Inventors: Charlotte A. Kensil, Sean Soltysik, Dante J. Marciani
  • Patent number: 5352452
    Abstract: Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: October 4, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Kohnert, Rainer Rudolph
  • Patent number: 5352453
    Abstract: Pharmaceutical compositions containing non-glycosylated human tissue type plasminogen activator (t-PA) having enzymatic activity of at least 0.1 MU/ml are disclosed. The compositions have a pH of from 4.5 to 6, contain citrate, and at least one other compound.
    Type: Grant
    Filed: August 6, 1991
    Date of Patent: October 4, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Kohnert, Rainer Rudolph
  • Patent number: 5332663
    Abstract: 7-amino-cephalosporanic acids having the formula ##STR1## are obtained by submitting compounds having the following formula to enzymatic conversion: ##STR2## wherein R represents H, OH, O--CO--R", R" being an alkyl radical with from 1 to 4 carbon atoms, R.sup.1 represents a carboxylic group. The reaction is carried out in the presence of a microorganism selected from the Pseudomonas, Bacillus, Achromobacter genera, or in the presence of an enzyme, either free or immobilized, derived therefrom.
    Type: Grant
    Filed: July 14, 1992
    Date of Patent: July 26, 1994
    Assignee: Ministero dell'Universita' e della Ricerca Scientifica e Tecnologica
    Inventors: Ezio Battistel, Pietro Cesti, Giuliana Franzosi, Vilhelmus van der Goes
  • Patent number: 5276017
    Abstract: Therapeutic and diagnostic applications by the manipulation of a unique protein produced by trophoblasts and defined by the monoclonal antibody FDC-6 are provided by this invention.
    Type: Grant
    Filed: September 25, 1990
    Date of Patent: January 4, 1994
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Ronald F. Feinberg, Harvey J. Kliman
  • Patent number: 5273965
    Abstract: Methods for enhancing the transport of pharmacologically active substances across mucous membranes of an animal by administration of pharmaceutical compositions comprising modified saponins or fractions thereof obtainable by modification of a crude Quillaja saponaria extract or by modification of purified saponins obtainable from a crude Quillaja saponaria extract. Also disclosed are modified saponins having reduced irritability wherein the fatty acid moiety is removed by hydrolysis or the aldehyde group is reduced. Also disclosed are pharmaceutical compositions comprising the modified saponins of the invention.
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: December 28, 1993
    Assignee: Cambridge Biotech Corporation
    Inventors: Charlotte A. Kensil, Sean Soltysik, Dante J. Marciani
  • Patent number: 5262323
    Abstract: The novel strain JHCC 4279 of Bacillus thuringiensis and insecticidal compositions containing insecticidal protein endotoxin produced by the strain JHCC 4279 which protects plants from Diabrotica by exposing larvae to the insecticidal protein endotoxin produced by the strain. Novel genes for insecticidal proteins may be isolated from strain JHCC 4279.
    Type: Grant
    Filed: October 31, 1991
    Date of Patent: November 16, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: Sheila Baird, Susan Ely, Graham M. Gibb, Janet M. Tippett
  • Patent number: 5260074
    Abstract: Disclosed are gastric acid-resistant polymer-coated digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods of treating digestive disorders, impaired liver function, cystic fibrosis, regulating the absorption of dietary cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
    Type: Grant
    Filed: June 22, 1992
    Date of Patent: November 9, 1993
    Assignee: Digestive Care Inc.
    Inventor: Tibor Sipos
  • Patent number: 5244794
    Abstract: Root organ cultures of the monocot genus Allium were successfully grown in culture medium. In a preferred bioreactor system, the roots themselves can be grown and harvested as a source of various Allium flavors and/or the growing roots can be reacted with various nutrients to produce Allium flavor compounds independent of the root harvesting. The root cultures of the present invention produce quantities of onion and onion-like flavor compounds comparable to those found in onion bulbs.Flavor precursors arThis invention was made in part under NSF Grant No. 85-03183. The U.S. Government has certain rights to this invention.
    Type: Grant
    Filed: June 28, 1991
    Date of Patent: September 14, 1993
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Christopher Prince, Michael L. Shuler
  • Patent number: 5232828
    Abstract: A method for improving recovery of cells from liquid suspension by centrifuqation. The method comprises coating the interior of centrifuge containers with a solution comprising an amphipathic compound prior to introduction of the cell suspension and centrifugation. The method is suited for recovery or concentration of rare cells from dilute suspensions, for example when rare cells are isolated from a sample by sorting on a flow cytometer.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: August 3, 1993
    Assignee: Becton, Dickinson and Company
    Inventors: Janette T. Phi-Wilson, Diether J. Recktenwald
  • Patent number: 5227299
    Abstract: The present invention relates to a novel NADH kinase which has high stability and is specific for NADH, and a process for producing the NADH kinase by culturing a yeast belonging to the genus Pichia in a culture medium, and this enzyme permits highly sensitive determination of NADH alone and hence is useful in the field of clinical medicine.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: July 13, 1993
    Assignee: Noda Institute for Scientific Research
    Inventors: Tsuyoshi Ohno, Masaru Suzuki, Tatsuo Horiuchi