Patents Examined by Kristin Larson
  • Patent number: 5580962
    Abstract: A thrombolytic, parenterally administrable drug containing activated protein C is provided for. The drug is free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and activated protein C.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: December 3, 1996
    Assignee: Immuno Aktiengesellschaft
    Inventors: Johann Eibl, Yendra Linnau, Anton Philapitsch, Hans P. Schwarz
  • Patent number: 5578304
    Abstract: Disclosed are gastric acid-resistant polymer-coated, buffered digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods for treating digestive disorders, pancreatic enzyme insufficiency, impaired liver function, and cystic fibrosis for regulating the absorption of dietary iron and cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: November 26, 1996
    Assignee: Digestive Care Inc.
    Inventor: Tibor Sipos
  • Patent number: 5556624
    Abstract: A method for immunopotentiating and protecting an animal from an infection caused by E. coli is described. The method comprises administering a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L. to the animal.
    Type: Grant
    Filed: November 1, 1994
    Date of Patent: September 17, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki
  • Patent number: 5556785
    Abstract: A composition containing powdered Lactobacillus brevis subsp. coagulans is used to enhance the immunological functions of a patient, particularly with respect to increasing interferon production, 2-5A synthetase activity and Natural Killer activity.
    Type: Grant
    Filed: October 27, 1993
    Date of Patent: September 17, 1996
    Assignees: Institut Pasteur de Kyoto, Shinwa Pharmaceutical Co., Ltd., Nitto Pharmaceutical Industries Ltd.
    Inventor: Tsunataro Kishida
  • Patent number: 5556625
    Abstract: A method of reducing the symptoms of diarrhea by administering to an animal a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: September 17, 1996
    Assignee: Eisai Co., Ltd.
    Inventors: Seiichi Araki, Mamoru Suzuki, Masatoshi Fujimoto, Tadashi Ueki
  • Patent number: 5554368
    Abstract: A biologically pure culture of Pseudomonas syringae having the identifying characteristics of the deposited strain designated as ATCC 55389 is disclosed. A composition for inhibiting microbial decay on fruit is disclosed, the composition including a strain of Pseudomonas syringae having the identifying characteristics of the deposited strain designated as ATCC 55389 and a carrier. The composition has a concentration of the strain in the carrier which is sufficient to significantly inhibit microbial decay on the fruit. Additionally, a method for inhibiting microbial decay on fruit is disclosed including the step of exposing the fruit to a composition which includes a sufficient concentration of a strain of Pseudomonas syringae having the characteristics of the deposited strain as ATCC 55389 to significantly inhibit microbial decay.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: September 10, 1996
    Assignee: EcoScience Corporation
    Inventors: James P. Stack, Steven N. Jeffers, Baruch Sneh, Teresa S. Wright
  • Patent number: 5549889
    Abstract: The present invention relates to a newly discovered Streptomyces species, Streptomyces dicklowii, which exhibits nematocidal and fungicidal activity in agricultural and horticultural settings. S. dicklowii can be used as a biocontrol agent in the treatment and prevention of nematode and/or fungal infection in plants, and particularly in commercially important crop plants.
    Type: Grant
    Filed: June 11, 1993
    Date of Patent: August 27, 1996
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Bert M. Zuckerman, M. B. Dicklow, Nahum Marban-Mendoza
  • Patent number: 5545722
    Abstract: Disclosed is a hepatocyte-growth agent which comprises a polysaccharide or a derivative such as heparin, heparan sulfate, chondroitin sulfate and dextran sulfate and a hepatocyte-growth factor (hHGF) obtained by purification of plasma or recombination, by which activity of the hHGF is strengthened, and an hHGF molecule is stabilized.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: August 13, 1996
    Assignee: Mitsubishi Kasei Corporation
    Inventor: Daiji Naka
  • Patent number: 5545555
    Abstract: A microbial transport medium for the collection, transport and storage of samples suspected of having Chlamydia, Mycoplasma, Ureaplasma or viral pathogens comprises a balanced salt solution, a proteinaceous stabilizer, and carbohydrate and amino acid nutrient sources. The medium is buffered to maintain physiological pH and includes a pH indicator in order to maintain pH fluctuation. The medium further comprises antimicrobial and antifungal agents and can comprise gelatin. Samples can be stored in the medium at temperatures ranging from room temperature to minus 70.degree. C. Additionally, the transport medium can be used in standardized commercial ELISA and PCR assays.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: August 13, 1996
    Assignee: Microtest, Inc.
    Inventors: Stephen G. Racioppi, James P. Brinker
  • Patent number: 5543142
    Abstract: An improved method for regulating plant growth has been developed. The plant soil medium in which plants are grown is regulated to a pH in the range of about 2 to about 9, and preferably to a range of about 6.8 to 7.2. Then, Actinomyces viscosus strain GA is applied directly to the plant soil medium. The Actinomyces viscosus, GA delivers a natural biological control agent to plants, rather than a synthetic agent, which acts as a growth retardant and a flower initiator.
    Type: Grant
    Filed: April 6, 1994
    Date of Patent: August 6, 1996
    Assignee: Natural Industries, Inc.
    Inventor: William M. Kowalski
  • Patent number: 5523395
    Abstract: Disclosed are two lectin species isolated from the hemolymph of Japanese horseshoe crabs and Southern horseshoe crabs which bind to N-acetylneuraminic acid and N-glycolylneuraminic acid, but not to N-acetylglucosamine, glucoronic acid, or N-acetylgalactosamine.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: June 4, 1996
    Assignee: Maruha Corporation
    Inventors: Seiichi Ohkuma, Khomei Yanagi, Kuniharu Wada, Isami Tsuboi, Shoji Kimura, Masahito Matsukawa, Nobuyuki Sato
  • Patent number: 5512279
    Abstract: The invention relates to the biological control of Dipteran pests other than the mosquito, which comprises the use of Bacillus thuringiensis isolate HD 541 (NCIMB 40373) or HD 571 (NCIMB 40374), or a mutant, recombinant or derivative thereof, or insecticidal material derived therefrom.
    Type: Grant
    Filed: April 15, 1993
    Date of Patent: April 30, 1996
    Assignee: Agricultural Genetics Company Limited
    Inventors: Paul Jarrett, Philip F. White, Nicole J. Pethybridge
  • Patent number: 5501852
    Abstract: This invention relates to a strain of Bacillus thuringiensis M200, a sample of which has been deposited under the accession number NCIMB 40385, or a variant, derivative or mutant thereof having entomocidal activity against lepidopterous pests. The invention also relates to the use of the said strain for control of insect pests.
    Type: Grant
    Filed: December 28, 1994
    Date of Patent: March 26, 1996
    Assignee: Agricultural Genetics Company Limited
    Inventors: Martin-Paul Meadows, Deborah J. Ellis, Paul Jarrett
  • Patent number: 5482838
    Abstract: Purified trypsin-sensitive agent or analog thereof, able to downregulate collagenase, PAI-1 and .beta.APP expression in senescent cells isolatable from culture medium having growing fibroblasts or U937 promyelocytic cells.
    Type: Grant
    Filed: February 8, 1993
    Date of Patent: January 9, 1996
    Assignee: Geron Corporation
    Inventor: Michael D. West
  • Patent number: 5480827
    Abstract: A three-dimensional solid support for the in vitro cultivation of cells consists essentially of porous polycrystalline aragonite in the form of a cylinder, sphere or plate. The support may be used to successively grow layers of different cells on the support, and is particularly useful for cultivating endothelial cells, fibroblasts and bone marrow cells.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: January 2, 1996
    Assignee: Inoteb
    Inventors: Genevieve Guillemin, Pascal Christel, Jean-Louis Patat, Alain Meunier
  • Patent number: 5472690
    Abstract: The mycoherbicide of the present invention is effective in the control of Calamagrostis canadensis and/or related grasses, particularly in areas undergoing reforestation. The mycoherbicide includes one or both of Fusarium nivalis (ATCC #26050) and a fungus, Colletotrichum calamagrostidis (PFC-215, ATCC #74287), isolated from a diseased plant of C. canadensis var. canadensis. The mycoherbicidal formulation preferably includes an allelopathic agent, such as straw, straw-based material, straw extract, grass extract or an endophyte. An especially effective treatment was demonstrated with C. calamagrostidis (PFC-215) and an inoculum of endophytic Fusarium nivalis. An embodiment of a method of treatment according to the present invention includes the application of endophytes of reduced virulence to grass bordering a target area or in grazing lands, to prevent either natural or inoculative infection.
    Type: Grant
    Filed: August 5, 1993
    Date of Patent: December 5, 1995
    Assignee: Forestry Canada
    Inventor: Richard S. Winder
  • Patent number: 5460812
    Abstract: Disclosed are gastric acid-resistant polymer-coated buffered digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods of treating digestive disorders, pancreatic enzyme insufficiency, impaired liver function, cystic fibrosis, for regulating the absorption of dietary iron and cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
    Type: Grant
    Filed: September 29, 1993
    Date of Patent: October 24, 1995
    Assignee: Digestive Care Inc.
    Inventor: Tibor Sipos
  • Patent number: 5432067
    Abstract: There is disclosed a process for the production of biotin, in which a culture of a microorganism of the genus Sphingomonas, having an ability to produce biotin, is prepared in a medium, and biotin produced and accumulated in the medium is collected. Also disclosed are microorganisms of the genus Sphingomonas, having an ability to produce biotin, which are useful for this production process of the present invention.
    Type: Grant
    Filed: August 25, 1993
    Date of Patent: July 11, 1995
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Kazuo Kumagai, Misao Miki, Emiko Kawano, Satoshi Mitsuda
  • Patent number: 5427787
    Abstract: A biocidal formulation with improved resistance to ultraviolet rays comprising: (a) an appropriate biocide which is Bacillus thuringiensis; (b) an anti-ultraviolet agent selected from the group consisting of 2-(2-H-benzotriazole-2-yl)-phenol and their derivatives represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 are independently selected from the group consisting of alkyl, aryl, and alkylaryl groups; (c) pre-gelatinized starch; and (d) natural starch, the biocide, the anti-ultraviolet agent, the pre-gelatinized starch and the natural starch are mixed then baked at 60.degree.-90.degree. C. to form the biocidal formulation.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: June 27, 1995
    Assignee: Industrial Technology Research Institute
    Inventors: Chien-Chun Yang, I-Horng Pan, Mei-Hueih Chen, Suey-Sheng Kao, Yeong-Sheng Tsai
  • Patent number: 5425941
    Abstract: The present invention is drawn to isolates of Candida oleophila which are effective for the control of postharvest diseases in fruit and to biocontrol compositions which include such isolates. A method of utilizing the isolates to inhibit pathogens which cause postharvest diseases is also described. The organisms were isolated from the surface of tomato fruit and are useful for the control of a variety of fruit-rot pathogens in a variety of fruits.
    Type: Grant
    Filed: October 15, 1993
    Date of Patent: June 20, 1995
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Charles L. Wilson, Michael E. Wisniewski, Edo Chalutz