Abstract: A thrombolytic, parenterally administrable drug containing activated protein C is provided for. The drug is free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and activated protein C.
Type:
Grant
Filed:
April 3, 1995
Date of Patent:
December 3, 1996
Assignee:
Immuno Aktiengesellschaft
Inventors:
Johann Eibl, Yendra Linnau, Anton Philapitsch, Hans P. Schwarz
Abstract: Disclosed are gastric acid-resistant polymer-coated, buffered digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods for treating digestive disorders, pancreatic enzyme insufficiency, impaired liver function, and cystic fibrosis for regulating the absorption of dietary iron and cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
Abstract: A method for immunopotentiating and protecting an animal from an infection caused by E. coli is described. The method comprises administering a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L. to the animal.
Abstract: A composition containing powdered Lactobacillus brevis subsp. coagulans is used to enhance the immunological functions of a patient, particularly with respect to increasing interferon production, 2-5A synthetase activity and Natural Killer activity.
Abstract: A method of reducing the symptoms of diarrhea by administering to an animal a composition containing Rosa roxburghii, Artemisiae argyi folium, and Brassica oleracea var. capitata L.
Abstract: A biologically pure culture of Pseudomonas syringae having the identifying characteristics of the deposited strain designated as ATCC 55389 is disclosed. A composition for inhibiting microbial decay on fruit is disclosed, the composition including a strain of Pseudomonas syringae having the identifying characteristics of the deposited strain designated as ATCC 55389 and a carrier. The composition has a concentration of the strain in the carrier which is sufficient to significantly inhibit microbial decay on the fruit. Additionally, a method for inhibiting microbial decay on fruit is disclosed including the step of exposing the fruit to a composition which includes a sufficient concentration of a strain of Pseudomonas syringae having the characteristics of the deposited strain as ATCC 55389 to significantly inhibit microbial decay.
Type:
Grant
Filed:
December 3, 1993
Date of Patent:
September 10, 1996
Assignee:
EcoScience Corporation
Inventors:
James P. Stack, Steven N. Jeffers, Baruch Sneh, Teresa S. Wright
Abstract: The present invention relates to a newly discovered Streptomyces species, Streptomyces dicklowii, which exhibits nematocidal and fungicidal activity in agricultural and horticultural settings. S. dicklowii can be used as a biocontrol agent in the treatment and prevention of nematode and/or fungal infection in plants, and particularly in commercially important crop plants.
Type:
Grant
Filed:
June 11, 1993
Date of Patent:
August 27, 1996
Assignee:
Research Corporation Technologies, Inc.
Inventors:
Bert M. Zuckerman, M. B. Dicklow, Nahum Marban-Mendoza
Abstract: Disclosed is a hepatocyte-growth agent which comprises a polysaccharide or a derivative such as heparin, heparan sulfate, chondroitin sulfate and dextran sulfate and a hepatocyte-growth factor (hHGF) obtained by purification of plasma or recombination, by which activity of the hHGF is strengthened, and an hHGF molecule is stabilized.
Abstract: A microbial transport medium for the collection, transport and storage of samples suspected of having Chlamydia, Mycoplasma, Ureaplasma or viral pathogens comprises a balanced salt solution, a proteinaceous stabilizer, and carbohydrate and amino acid nutrient sources. The medium is buffered to maintain physiological pH and includes a pH indicator in order to maintain pH fluctuation. The medium further comprises antimicrobial and antifungal agents and can comprise gelatin. Samples can be stored in the medium at temperatures ranging from room temperature to minus 70.degree. C. Additionally, the transport medium can be used in standardized commercial ELISA and PCR assays.
Abstract: An improved method for regulating plant growth has been developed. The plant soil medium in which plants are grown is regulated to a pH in the range of about 2 to about 9, and preferably to a range of about 6.8 to 7.2. Then, Actinomyces viscosus strain GA is applied directly to the plant soil medium. The Actinomyces viscosus, GA delivers a natural biological control agent to plants, rather than a synthetic agent, which acts as a growth retardant and a flower initiator.
Abstract: Disclosed are two lectin species isolated from the hemolymph of Japanese horseshoe crabs and Southern horseshoe crabs which bind to N-acetylneuraminic acid and N-glycolylneuraminic acid, but not to N-acetylglucosamine, glucoronic acid, or N-acetylgalactosamine.
Abstract: The invention relates to the biological control of Dipteran pests other than the mosquito, which comprises the use of Bacillus thuringiensis isolate HD 541 (NCIMB 40373) or HD 571 (NCIMB 40374), or a mutant, recombinant or derivative thereof, or insecticidal material derived therefrom.
Type:
Grant
Filed:
April 15, 1993
Date of Patent:
April 30, 1996
Assignee:
Agricultural Genetics Company Limited
Inventors:
Paul Jarrett, Philip F. White, Nicole J. Pethybridge
Abstract: This invention relates to a strain of Bacillus thuringiensis M200, a sample of which has been deposited under the accession number NCIMB 40385, or a variant, derivative or mutant thereof having entomocidal activity against lepidopterous pests. The invention also relates to the use of the said strain for control of insect pests.
Type:
Grant
Filed:
December 28, 1994
Date of Patent:
March 26, 1996
Assignee:
Agricultural Genetics Company Limited
Inventors:
Martin-Paul Meadows, Deborah J. Ellis, Paul Jarrett
Abstract: Purified trypsin-sensitive agent or analog thereof, able to downregulate collagenase, PAI-1 and .beta.APP expression in senescent cells isolatable from culture medium having growing fibroblasts or U937 promyelocytic cells.
Abstract: A three-dimensional solid support for the in vitro cultivation of cells consists essentially of porous polycrystalline aragonite in the form of a cylinder, sphere or plate. The support may be used to successively grow layers of different cells on the support, and is particularly useful for cultivating endothelial cells, fibroblasts and bone marrow cells.
Abstract: The mycoherbicide of the present invention is effective in the control of Calamagrostis canadensis and/or related grasses, particularly in areas undergoing reforestation. The mycoherbicide includes one or both of Fusarium nivalis (ATCC #26050) and a fungus, Colletotrichum calamagrostidis (PFC-215, ATCC #74287), isolated from a diseased plant of C. canadensis var. canadensis. The mycoherbicidal formulation preferably includes an allelopathic agent, such as straw, straw-based material, straw extract, grass extract or an endophyte. An especially effective treatment was demonstrated with C. calamagrostidis (PFC-215) and an inoculum of endophytic Fusarium nivalis. An embodiment of a method of treatment according to the present invention includes the application of endophytes of reduced virulence to grass bordering a target area or in grazing lands, to prevent either natural or inoculative infection.
Abstract: Disclosed are gastric acid-resistant polymer-coated buffered digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods of treating digestive disorders, pancreatic enzyme insufficiency, impaired liver function, cystic fibrosis, for regulating the absorption of dietary iron and cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.
Abstract: There is disclosed a process for the production of biotin, in which a culture of a microorganism of the genus Sphingomonas, having an ability to produce biotin, is prepared in a medium, and biotin produced and accumulated in the medium is collected. Also disclosed are microorganisms of the genus Sphingomonas, having an ability to produce biotin, which are useful for this production process of the present invention.
Abstract: A biocidal formulation with improved resistance to ultraviolet rays comprising: (a) an appropriate biocide which is Bacillus thuringiensis; (b) an anti-ultraviolet agent selected from the group consisting of 2-(2-H-benzotriazole-2-yl)-phenol and their derivatives represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 are independently selected from the group consisting of alkyl, aryl, and alkylaryl groups; (c) pre-gelatinized starch; and (d) natural starch, the biocide, the anti-ultraviolet agent, the pre-gelatinized starch and the natural starch are mixed then baked at 60.degree.-90.degree. C. to form the biocidal formulation.
Type:
Grant
Filed:
November 15, 1993
Date of Patent:
June 27, 1995
Assignee:
Industrial Technology Research Institute
Abstract: The present invention is drawn to isolates of Candida oleophila which are effective for the control of postharvest diseases in fruit and to biocontrol compositions which include such isolates. A method of utilizing the isolates to inhibit pathogens which cause postharvest diseases is also described. The organisms were isolated from the surface of tomato fruit and are useful for the control of a variety of fruit-rot pathogens in a variety of fruits.
Type:
Grant
Filed:
October 15, 1993
Date of Patent:
June 20, 1995
Assignee:
The United States of America as represented by the Secretary of Agriculture
Inventors:
Charles L. Wilson, Michael E. Wisniewski, Edo Chalutz