Patents Examined by Kualid Masood
  • Process for preparing hepatitis A (HAV) antigens and vaccines
    Patent number: 5731187
    Abstract: Process for preparing hepatitis A (HAV) antigens and vaccines.The HAV virus is multiplied on competent cells, the infected cells are lysed, the supernatant is recovered and the purification is carried out by a chromatographic procedure on an anion-exchange support and a gel filtration procedure, the purification procedures being carried out in the presence of a detergent, and the chromatographic procedure being carried out under conditions which retain the virions or viral capsids, which are then eluted.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: March 24, 1998
    Assignee: Pasteur Merteux Serums Et Vaccins Societe Anonyme
    Inventors: Bernard Fanget, Alain Francon