Abstract: The invention is directed to a method for controlling the operating parameters determining the thermal metabolism of a premature or newborn disposed in an incubator. These operating parameters include the incubator air temperature and the incubator humidity. The method is improved in such a manner that the adjustment of the parameters is coupled to the combination thereof optimizing the thermal metabolism without the necessity of a complex multiple step adjustment for each individual parameter. The method is characterized in that a primary control circuit for controlling the first parameter supplies the actual value corresponding thereto as a control parameter to a logic generator which determines a sequence value by means of a logic function. This sequence value is conducted to a secondary circuit as a desired value for the adjustment of the second parameter.

Abstract: A therapeutic pad for relief of headache-associated head, temple, neck and upper back pain includes a lower portion substantially defining, in surface geometry, a rectangle having major and a minor bases and, further, having an axis of symmetry co-parallel to the minor bases. The therapeutic pad also includes an upper portion substantially defining, in surface geometry, an elongate wing-like shape having a major axis of about double the length of the major bases of the rectangle of the lower portion, and having a minor axis which is an axis of symmetry co-linear to the axis of symmetry of the lower portion. The upper portion includes elements for selectably securing to each other portions of lateral ends of the wing-like shape.

Abstract: An implantable cardiac monitor is arranged for detecting both arrhythmias and ischemia of the human heart. The monitor includes subcutaneous electrodes for establishing electrical contact with the heart and a sense amplifier coupled to each electrode for generating an electrocardiogram of a heart beat sensed at each of the electrodes. The electrocardiograms are digitized and the digital samples thereof are stored in a memory. A microprocessor processes the digital samples of the electrocardiograms and generates characterizing data indicative of the physiology of the heart. The cardiac monitor includes telemetry to permit the cardiac data to be interrogated externally of the patient for obtaining the generated cardiac data indicative of arrhythmic and ischemic episodes.

Abstract: A conformable PEMF transducer (FIG. 1a-1b) used for PEMF therapy (such as for healing non-union fractures of the hip). The transducer (FIG. 3 ) includes electrically conducting primary, secondary, and sense windings (31, 32, 33) formed into a transducer coil integral with non-conducting semi-rigid structural windings (34). The structural windings provide structural support for the coil so that it is formable into a selected anatomical contour, but still flexibly conformable to accommodate normal patient motion. Control electronics (FIG. 4 ) includes a PEMF processor (41) that executes a PEMF program for providing pulsing current to the front and back transducers at predetermined intervals, thereby activating the electromagnetic field according to a prescribed PEMF regimen.

Abstract: A photo-electric pulse measuring probe includes a pair of supporting members which have a light emitting element and a light receiving element adjacent first end portions thereof, respectively, in such a manner that the light emitting element and the light receiving elements are confronted with each other, and which are swingably coupled to each other at the other end portions thereof. The light emitting element and the light receiving element are covered with elastic members, respectively, and wavy surfaces are formed in the mating surfaces of the elastic members, respectively, so that a user's finger is supported by a number of points during measurement.

Abstract: To obtain optical one-way transmission of bioelectrical potential differences between electrodes placed on a patient and the evaluation apparatus, one of the electrodes placed on the patient is designated as the reference electrode. The potentials of all the other electrodes are referred to this electrode, and the signals derived from the potential differences so obtained are amplified, multiplexed, converted analog/digital and transmitted in coded form. At least one of the potential differences recorded by the evaluation apparatus is derived from the difference between two transmitted signals. The number of signals transmitted can thus be less than the number of potential differences recorded. This process is particularly useful for transmitting electrocardiogram signals (ECG signals) to an ECG apparatus which produces twelve standard derivatives. The optical transmission can also be performed by an optical fibre.

Abstract: A diagnosis device which includes a probe provided at a front end of an elongate insertion portion, and has the function of angling this probe. An angle portion is provided between the insertion portion and the probe, and the angle portion includes a pair of tubular segments pivotally connected together. The pair of segments are connected to the front end of the insertion portion and the rear end of the probe, respectively. A soft protective tube is disposed inside the pair of segments at the angle portion. An operating member is connected at one end thereof to a manipulation mechanism mounted on a body, and is connected at the other end thereof to the front segment of the angle portion. The operating member is disposed outside the protective tube at the angle portion.

Abstract: A photo-pulse from a photo-pulse generating apparatus is branched, where one branch is radiated to an examined body and the reflected light reflected within the examined body is delayed in time in proportion to the depth from the surface of the examined body and is led to a time-analyzing reflected light measuring apparatus. In this measuring apparatus, the other branched reference photo-pulse or reference signal pulse is input as delayed by the time for which the photo-pulse reflected within the examined body returns and only the reflected light component synchronized with the entering timing of this reference light pulse is analyzed in the time and is detected. By varying the detection sensitivity of this measuring apparatus in response to the depth from the surface of the examined body, the interior can be observed.

Abstract: An apparatus for administering electrical aversive stimulus is provided. The apparatus includes a remote transmitter, a receiver/stimulator, and an electrode. The receiver/stimulator is activated by an electromagnetic signal generated by the transmitter. In response, the receiver/stimulator generates an electrical stimulus pulse which is administered to the individual through the electrode. The receiver/stimulator and electrode are worn by the individual. Stimulation indicator means on the receiver/stimulator provides a positive indication that the stimulation has been administered to the individual. Various characteristics of the electrical stimulus pulse may be adjusted to vary the individual's perceived averseness of the stimulus. A method of treatment utilizing the apparatus of this invention is also provided.

Abstract: The invention relates to combined neuroepithelial electrode and sample delivery devices which deliver a stimulant to neuroepithelial tissue and measure the bioelectric response of the tissue to the stimulant. Some devices also include an evacuation catheter which removes the stimulant from a subject immediately after stimulation, thereby limiting the locus of stimulated tissue. The invention also relates to methods of using these devices to stimulate and measure the response of neuroepithelial tissue, particularly the neuroepithelial tissue of the human vomeronasal organ.

Abstract: A two- and three-dimensional autoradiographical imaging system is provided which includes a charge coupled device for detecting the emission of radioactively labeled substances from materials such as tissue samples, brains of humans or animals, or substances used in electrophoresis applications. In a first aspect, a radioactively labeled substance is included in a tissue sample. The tissue sample is sequentially imaged by a charge coupled device and a sectioning tool such as a microtome to produce a plurality of two-dimensional images. A three-dimensional image of the tissue sample is generated by further processing of the plurality of two-dimensional images derived from the charge coupled device. In a further aspect of the invention, a charge coupled device is utilized to provide realtime imaging of metabolic or physiological parameters involved in brain activity.

Abstract: A system for continuously supplying supplemental therapeutic oxygen to a patient to enhance atmospheric breathing comprising an oxygen supply source for continuously supplying low pressure low volume oxygen to a patient at relatively low pressures and relatively low flow rates to supplement normal atmospheric breathing; flexible oxygen supply tube devices for supplying oxygen from said oxygen supply source to the patient; and a continuous one-piece constant diameter flexible elongated tracheal tube member having a continuous constant diameter passage extending therethrough and being flexible when inserted into an operative position within the trachea to provide therein an intermediate curved side wall portion extending between a proximate end side wall portion having an unrestricted inlet opening therein located posterior of the neck of a patient and a straight distal side wall portion located in the trachea and extending downwardly therein and having an unrestricted distal end outlet opening located in upwar

Abstract: Large surface area electrode for use with a power supply having a more uniform current density distribution for contacting the exposed surface of a living body having a contour. The electrode comprises a layer of flexible conductive material of a predetermined geometrical shape and having first and second surfaces. The layer is normally relatively flat and is capable of assuming contours of the skin of the body when the electrode is placed in contact with the body with the first surface of the layer engaging the exposed surface of the body. The layer of conductive material has a central portion and a surrounding ring portion. The central portion and the surrounding ring portion have outer margins with edges. A flexible carrier layer is provided which is secured to the second surface of the layer of flexible conductive material and serves to support the central portion and the said surrounding portion so that the surrounding portion is spaced from and insulated from the central portion.

Abstract: A method is disclosed treating a tumor in a host by administering an ultrapurified polymerized hemoglobin solution to the host and thereafter administering ionizing radiation, such as X-rays, to the tumor. In a particularly preferred embodiment, the hemoglobin is bovine hemoglobin.

Abstract: A hand held breath analyzer is energized when a mouthpiece tube is put into position. An ejector mechanism expels the mouthpiece, which de-energizes the system. The insertion of the mouthpiece not only cocks the ejector mechanism but closes a cover on an exhaust manifold of a breath sample passage. The breath sample passage includes a sample chamber with a port to receive a sampling tube fitting, and an auxiliary port. The exhaust manifold is long relative to the length of the sampling chamber and terminates in an orifice by means of which ambient air is drawn across a thermistor. The sampling tube communicates with a fuel cell chamber, into which breath is drawn by a diaphragm pump arranged, in its normal, uncocked condition, to inhibit the entrance of contaminants into the chamber. The diaphragm pump is actuated in response to operation of the thermistor, through a relay-tripped toggle linkage.

Abstract: The invention relates to a fastening member (1) which is placed into a patient's cavity, such as a nostril, surrounded by tissue, and which allows a flow through the cavity through a port (5) and which can be joined to the measuring device via a suitable connecting piece (2). The fastening member (1) is flexible, whereby it can be formed, before being placed into the cavity, into a shape or size which fits better into the cavity, whereupon the fastening member, in the cavity, tends to return towards the original state by pressing against the surrounding wall of the cavity.

Abstract: A sensor for non-invasive measurement of oxygen saturation using the reflection method comprises a red transmitter (55), an infrared transmitter (58) and a receiver (57). The distances between the transmitters and the receiver are selected such that the length of the light path (60, 61) between the red transmitter (55) and the receiver (57) is substantially equal to the length of the light path (62, 63) between the infrared transmitter (58) and the receiver (57). The sensor comprises a further red transmitter (56) which is used for another application at the human body or another tissue characteristics where the depth of penetration at the various wavelengths is different from the shown example. Together with an appropriate oximeter, manual or automatic adaptation is possible. Further signal improvement may be obtained by autocorrelating the received signal, detecting its frequency and cross-correlating it with a pattern function of the same frequency.

Abstract: A sensor for non-invasive measurement of oxygen saturation using the reflection method comprises a red transmitter (55), an infrared transmitter (58) and a receiver (57). The distances between the transmitters and the receiver are selected such that the length of the light path (60, 61) between the red transmitter (55) and the receiver (57) is substantially equal to the length of the light path (62, 63) between the infrared transmitter (58) and the receiver (57). The sensor comprises a further red transmitter (56) which is used for another application at the human body or another tissue characteristics where the depth of penetration at the various wavelengths is different from the shown example. Together with an appropriate oximeter, manual or automatic adaptation is possible. Further signal improvement may be obtained by autocorrelating the received signal, detecting its frequency and cross-correlating it with a pattern function of the same frequency.

Abstract: Homogeneous membranes are disclosed which are composed of acrylic copolymers and are capable of absorbing 10% to 50% of their dry weight of water. The copolymers include a hydrophilic component which comprises acrylic esters having a poly(ethylene oxide) substituent as part of the alcohol moiety. The copolymers further comprise methacrylate and/or acrylate monomer units. The membranes are useful in the fabrication of biosensors, e.g., a glucose sensor, intended for in vivo use. Variations in the ratios of the monomeric components make possible the fabrication of membranes which have varying permeabilities.

Abstract: Apparatus particularly suited for implantation and/or extraction of osteal prostheses, comprising an ultrasonic power generator, regulator means for regulating the ultrasonic power generator in accordance with a predetermined algorithm, at least one transducer connected to the output line for converting said electrical energy to a linear mechanical motion, an acoustic transformer for increasing or decreasing peak-to-peak motion of the transducer and means for connecting the acoustic transformer to a surgical tool or a prosthetic device. The system suitably comprises a pair of transducers, one operating at each of 20 KHz and 40 KHz frequencies. Novel adapters for the four major types of osteal prosthesis are also provided.