Abstract: Example panel assemblies with frost inhibiting seal members are disclosed herein. Some example panel assemblies disclosed herein are particularly suited for creating a blast freezer (for food and other products) by using the panels in cordoning off a relatively small quick-freeze area within a larger freezer room. In some examples disclosed herein, a touch-and-hold fastener (e.g., VELCRO) connects two or more insulated flexible panels along their adjoining vertical edges to span the width of a supporting frame that is wider than a width of a single panel. To seal the joint and/or inhibit frost from developing along the joint, some example panel assemblies disclosed herein include a seal member with touch-and-hold elements plus sealing edges extending laterally in opposite directions. In some examples disclosed herein, the touch-and-hold elements couple two panels together while the sealing edges (e.g., foam strip or double looped sheet of material) block air from flowing through the touch-and-hold elements.