Abstract: The administration of a bronchodilator to a subject can be carried out using a new transdermal delivery system, a multilayer laminate where the drug is mixed in a gel which must pass through a barrier membrane prior to administration on the skin.
Type:
Grant
Filed:
July 31, 1987
Date of Patent:
November 29, 1988
Assignee:
Warner-Lambert Company
Inventors:
Niranjan M. Patel, Mohan B. Kabadi, Susan C. Moniot
Abstract: Phospholipids such as lecithins provide improved rheological properties for coating a rapidly moving web, such as a paper web. The phospholipids are preferably applied to the paper web as part of a coating mixture, and they can be included in the coating mixture by first including the phospholipid in a lubricant additive mixture that includes an emulsifier, a fatty acid vehicle, and plasticizer. The lubricant is well-suited for short-dwell coating methods.