Patents Examined by Lakshmi S. Channavajjala
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Patent number: 11968976Abstract: Active ingredient-carrying hydrogels include at least a hydrogel and an active ingredient. The active ingredient is released from the hydrogel onto an agricultural substrate or at an agricultural site in a controlled manner. The hydrogel may include lactose, which may be provided by a milk permeate waste stream from the dairy or food processing industry.Type: GrantFiled: November 4, 2019Date of Patent: April 30, 2024Assignee: WinField Solutions, LLCInventors: Danny Brown, Christine Colby, Lillian Magidow, Megan Barta, Dustyn Sawall
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Patent number: 11963947Abstract: Disclosed is a pharmaceutical combination comprising a glucokinase activator or a pharmaceutically acceptable salt thereof, an isotopic label thereof, a crystalline form thereof, a hydrate, a solvate, a diastereomeric or enantiomeric form thereof, and a DPP-IV inhibitor. Disclosed are a pharmaceutical composition and a fixed dose of a compound preparation, and the methods for preparing the pharmaceutical composition and the fixed dose of the compound preparation and the uses thereof.Type: GrantFiled: May 28, 2019Date of Patent: April 23, 2024Assignee: HUA Medicine (Shanghai) Ltd.Inventors: Li Chen, Yongguo Li, Gaosen Wang, Huisheng Gao
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Patent number: 11957660Abstract: An edaravone suspension for human oral administration includes edaravone particles, a dispersant, and water.Type: GrantFiled: September 22, 2022Date of Patent: April 16, 2024Assignee: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Tetsuo Hayama, Tomohiro Takahashi, Tomoyuki Omura, Kouji Hayashi, Munetomo Matsuda, Tadashi Miyazawa
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Patent number: 11918024Abstract: The present disclosure provides a coating composition including a pectin and a non-glycerol sugar alcohol. The pectin can be present in an amount by weight of at least 30.0% and at most 50.0%. The non-glycerol sugar alcohol can be present in an amount by weight of at least 10.0%) and at most 40.0%. The pectin can be present in a ratio of at least 1:1 and at most 5:1 relative to the non-glyercol sugar alcohol. The present disclosure also provides coating suspensions, coatings, and coated substrates related to the coating composition. The present disclosure also provides methods of making and using the coating compositions.Type: GrantFiled: April 3, 2018Date of Patent: March 5, 2024Assignee: Sensient Colors LLCInventors: Beverly A. Schad, Houston Smith
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Patent number: 11918689Abstract: An oral clonidine dosage unit providing a twenty-four hour extended release profile following a single dose administration is provided. The dosage unit comprises a pharmaceutically effective amount of a coated complex comprising clonidine bound to a cationic exchange resin, which is characterized by a twenty-four hour release profile. Dosage units may also provide an immediate release component.Type: GrantFiled: July 28, 2021Date of Patent: March 5, 2024Assignee: TRIS PHARMA INCInventor: Grishma Patel
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Patent number: 11911510Abstract: The invention relates to a solid oral extended release pharmaceutical dosage form comprising an extended release matrix formulation. The extended release matrix formulation comprises (1) at least one active agent, (2) at least one anionic surfactant, and (3) at least about 40% by weight (based on the weight of the extended release matrix formulation) of at least one polyethylene oxide. In certain embodiments, the molar ratio of the at least one anionic surfactant to the at least one active agent is from about 1:2 to about 10:1.Type: GrantFiled: August 30, 2018Date of Patent: February 27, 2024Assignee: Purdue Pharma L.PInventors: Ozgur Akcan, Richard Mannion
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Patent number: 11896719Abstract: The present invention provides for a method of treatment of IgA nephropathy, which method comprises: (i) identifying a pharmaceutically acceptable composition intended to treat IgA nephropathy comprising budesonide and one or more pharmaceutically-acceptable excipients that provide for a modified release of said budesonide after administration to the gastrointestinal tract, which composition fulfils the following requirements in a standard in vitro USP<711>/Ph.Eur. 2.9.3 dissolution test using a dissolution apparatus according to Apparatus 2 (Paddle Apparatus) of said test; (a) the composition fulfils the requirement that no more than about 10% of the budesonide is released into the dissolution medium within about 120 minutes, when the dissolution medium is aqueous and has a pH of about 1.Type: GrantFiled: January 23, 2023Date of Patent: February 13, 2024Assignee: CALLIDITAS THERAPEUTICS ABInventors: Eva Kristina Riesel, Lena Margareta Pereswetoff-Morath, Kari Sandvold, Christian Olle Andreas Pedersen
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Patent number: 11878025Abstract: Pharmaceutical compositions and stable nano-suspensions comprising mifepristone and at least one pharmaceutically acceptable excipient, which exhibit enhanced bioavailability compared to the currently marketed or commercially available formulations. Manufacturing process and methods of use are also provided. The pharmaceutical compositions are used for prevention, treatment or prophylaxis of disorders in human patients in need thereof. Oral pharmaceutical compositions of mifepristone, methods for their administration, processes for thei r production, and use of these compositions are described for the treatment of diseases for which mifepristone is indicated.Type: GrantFiled: June 17, 2022Date of Patent: January 23, 2024Assignee: SLAYBACK PHARMA LLCInventors: Paras P. Jain, Somnath Devidas Navgire, Sumitra Ashokkumar Pillai
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Patent number: 11878075Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.Type: GrantFiled: April 18, 2019Date of Patent: January 23, 2024Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Sonali Sandip Bharate, Vikas Kumar, Mehak Gupta, Sumit Gandhi, Ajay Kumar, Sandip Bibishan Bharate, Ram Vishwakarma
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Patent number: 11872314Abstract: Disclosed herein are pharmaceutical powder compositions, methods of making such compositions, and uses thereof.Type: GrantFiled: August 28, 2020Date of Patent: January 16, 2024Assignee: Shin Nippon Biomedical Laboratories, Ltd.Inventor: Shunji Haruta
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Patent number: 11872328Abstract: Disclosed herein are devices/kits and methods for reducing, treating, preventing or eliminating post-operative adhesions in an intervention/target site within a body of a subject. The method comprises the steps of: introducing an applicator, configured for applying an anti-adhesive composition, into an intervention/target site within a body of a subject; applying the anti-adhesive composition onto the intervention/target site; and extracting the applicator from the body of the subject, wherein the method is performed during or following an interventional procedure.Type: GrantFiled: August 28, 2018Date of Patent: January 16, 2024Assignees: HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD., AZRIELI COLLEGE OF ENGINEERING JERUSALEMInventors: Yoav Mintz, Nikolai Kunicher, Tali Tavor Re'em
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Patent number: 11871744Abstract: A synergistic disinfectant composition comprises a C1-8 organic acid, an amino acid based surfactant, an anionic surfactant, and a stabilizing agent. The C1-8 organic acid may include two or more types of the C1-8 organic acids with at least one of the C1-8 organic acids is alpha hydroxyl acid. The disinfectant composition has an antimicrobial activity of log reduction of at least 2 under Biocidal Product Registration (BPR) standard EN13727, EN1276, EN13624 or EN1499, and/or the EPA standard that applies the “Quantitative Methods for Evaluating the Activity of Microbicides used on Hard, Non-Porous Surface” issued by the Organisation for Economic Co-operation and Development (OECD). In addition, the disinfectant composition may be stable during storage and retain their antimicrobial activity after at least one month at 40° C. When desired, the synergistic disinfectant composition may further comprise an oxidizing agent.Type: GrantFiled: November 1, 2022Date of Patent: January 16, 2024Assignee: Diversey, Inc.Inventors: Farida H. Tinwala, Xiaobao Li, Decio R. Silva, Jr., Yogaraj Nabar, Arnoud Ubald Maria Gengler
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Patent number: 11857671Abstract: An improved medical implant device directed to, inter alia, (i) avoiding unwanted initial drug “burst” problems, (ii) providing a more level amount of drug delivery, (iii) reducing blood clotting, (iv) reducing the amount of drug material that remains in the implant device, and/or (v) novel materials for an implant device.Type: GrantFiled: March 30, 2021Date of Patent: January 2, 2024Inventor: Robert W. Adams
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Patent number: 11826478Abstract: The invention provides compositions and methods for delivering vitamin D to a human subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to human skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.Type: GrantFiled: February 12, 2021Date of Patent: November 28, 2023Assignee: TRS II, LLCInventors: Ted Schwarzrock, Gary Cleary
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Patent number: 11826352Abstract: An edaravone suspension for human oral administration includes edaravone particles, a dispersant, and water.Type: GrantFiled: May 5, 2021Date of Patent: November 28, 2023Assignee: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Tetsuo Hayama, Tomohiro Takahashi, Tomoyuki Omura, Kouji Hayashi, Munetomo Matsuda, Tadashi Miyazawa
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Patent number: 11813263Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.Type: GrantFiled: August 15, 2022Date of Patent: November 14, 2023Assignee: Aerovate Therapeutics, Inc.Inventors: Ben Dake, Ralph Niven
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Patent number: 11806433Abstract: Described herein are alcohol-resistant oral pharmaceutical compositions and dosage forms that exhibit reduced drug release in the presence of alcohol. The compositions comprise a substrate comprising a controlled release formulation of lorazepam and an alcohol-resistant coating surrounding the substrate.Type: GrantFiled: October 25, 2018Date of Patent: November 7, 2023Assignee: EDGEMONT PHARMACEUTICALS, LLC TRUSTInventors: Douglas Saltel, Michael Vachon
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Patent number: 11801231Abstract: Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition HOCH2—(CHOH)n—CH2NR1R2??(I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.Type: GrantFiled: December 19, 2018Date of Patent: October 31, 2023Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Katie F. Wlaschin, Amanda C. Engler, Hannah C. Cohen, Yizhong Wang, Tao Gong, Tiffany T. Ton, Joel D. Oxman, Jie Yang
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Patent number: 11758906Abstract: A synergistic disinfectant composition comprises a C1-8 organic acid, an amino acid based surfactant, an anionic surfactant, and a stabilizing agent. The C1-8 organic acid may include two or more types of the C1-8 organic acids with at least one of the C1-8 organic acids is alpha hydroxyl acid. The disinfectant composition has an antimicrobial activity of log reduction of at least 2 under Biocidal Product Registration (BPR) standard EN13727, EN1276, EN13624 or EN1499, and/or the EPA standard that applies the “Quantitative Methods for Evaluating the Activity of Microbicides used on Hard, Non-Porous Surface” issued by the Organisation for Economic Co-operation and Development (OECD). In addition, the disinfectant composition may be stable during storage and retain their antimicrobial activity after at least one month at 40° C. When desired, the synergistic disinfectant composition may further comprise an oxidizing agent.Type: GrantFiled: April 6, 2022Date of Patent: September 19, 2023Assignee: Diversey, Inc.Inventors: Farida H. Tinwala, Xiaobao Li, Decio R. Silva, Jr., Yogaraj Nabar, Arnoud Ubald Maria Gengler
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Patent number: 11737988Abstract: Disclosed is a method of manufacturing a cardiovascular fixed-dose combination pharmaceutical dosage form that includes an anti-hypertensive active agent, a cholesterol-lowering active agent, and optionally, an enteric-coated aspirin or platelet inhibitor. The fixed-dose combination is prepared with at least two granulation solutions that are free of citric acid and enhance the aqueous solubility of the cholesterol-lowering agent in fixed-dose combination. The active agents in the resulting dosage form, which is also free of citric acid, have the same strength and release profiles as the same active agents prepared as a single formulation.Type: GrantFiled: April 17, 2019Date of Patent: August 29, 2023Assignee: CardioPharma, Inc.Inventors: Roy A. Stimits, Daniel Tyree Gregory, Jr., Wayne L. Whittingham, Stephan Dale Glenn, David P. Hause