Abstract: A smart inhaler system comprising an inhaler device for directed aerosol delivery facilitated by an adaptive nozzle and a mechanism for inhalation waveform modulation is provided. Methods of using the smart inhaler system for delivering an active agent to a target area of a lung of a subject are further provided.

Abstract: A lung-volume-reduction device for treating a lung to relieve symptoms of chronic obstructive pulmonary disease and/or emphysema. The device includes a chest-mounted housing and a conduit which projects from the housing through an aperture in the chest of the patient into the lung. The other end of the conduit is connected to flow-control device which may include a valve such as a one-way valve, check valve or pressure-actuated valve. The flow-control device is positioned within the chest-mounted housing. The lung-volume-reduction device permits gasses to pass through the conduit and flow-control device and vent to atmosphere external of the patient.

Abstract: An oral airway includes a first component having a first guiding surface and a second component having a second guiding surface. The first component and the second component are adapted to be removably coupled together such that the first guiding surface and the second guiding surface collectively define and encompass an interior passage through the oral airway that is dimensioned to direct, for example, a fiber-optic scope or an endotracheal tube extending through the interior passage for tracheal intubation. The first and second components are configured to be decoupled and independently removed from a patient's mouth without disrupting an endotracheal tube that has been extended through the conduit for tracheal intubation. The first and second components may be maintained in coupled disposition by an interlocking mechanical structure. The first and second components also may be maintained in coupled disposition by magnetism.

Abstract: An oral airway includes a first component having a first guiding surface and a second component having a second guiding surface. The first component and the second component are adapted to be removably coupled together such that the first guiding surface and the second guiding surface collectively define and encompass an interior passage through the oral airway that is dimensioned to direct, for example, a fiber-optic scope or an endotracheal tube extending through the interior passage for tracheal intubation. The first and second components are configured to be decoupled and independently removed from a patient's mouth without disrupting an endotracheal tube that has been extended through the conduit for tracheal intubation. The first and second components may be maintained in coupled disposition by an interlocking mechanical structure. The first and second components also may be maintained in coupled disposition by magnetism.

Abstract: A medication inhaler having an inhaler body with a medication container chamber for receiving a medication container and at least one air passage connecting the medication container chamber with external air and a mouthpiece axially engageable with the inhaler body and having a mouthpiece chamber for communication with a patient's respiratory system and a hollow medication delivery needle communicating with the mouthpiece chamber. The medication delivery needle extends toward the medication container chamber and has at least one opening for passing exterior air and medication from an interior space of a medication container in the medication container chamber through the needle and to mouthpiece chamber.

Abstract: A portable breathable gas delivery device including a pressure vessel for storing the breathable gas under pressure and a valve coupled to the pressure vessel through which the breathable gas can be selectively released. The pressure vessel is enclosed in a housing having a first portion that at least partially encloses the pressure vessel and a second portion that partially encloses a chamber coupled to the pressure vessel via the valve into which the breathable gas can be released for breathing by a user. The second portion together with a user's facial structure forms a substantially closed enclosure. The chamber has an opening shaped and formed to interface with the user's facial structure.

Abstract: A volume expansion system increases the storage volume for breathing gas in a closed-circuit breathing gas apparatus. A flow controller is coupled to an inhalation side of the closed-circuit breathing gas apparatus and is also coupled to an expandable reservoir. The flow controller defines a first flow path that allows breathing gas in the inhalation side to automatically flow into the expandable reservoir when pressure in the inhalation side exceeds a threshold. The flow controller can also include the means to define a second flow path that allows on-demand return of the breathing gas in the expandable reservoir to the inhalation side of the breathing gas apparatus.

Abstract: A system is provided for delivering a flow of breathing gas to an airway of a patient. The system includes a pressurizing flow module that generates a pressurized flow of breathing gas and a patient circuit coupled to the pressurizing flow module configured to communicate the flow of breathing gas to an airway of a patient. The system includes a sensor for monitoring a characteristic of a breathing pattern of the patient a controller that communicates with the sensor configured to increase a fraction of inspired carbon dioxide if the characteristic exceeds an upper threshold value and to provide servo-ventilation if the characteristic is less than a lower threshold value. The upper threshold value and the lower threshold value are changed based on the monitored characteristic of the breathing pattern of the patient.

Abstract: A catalytically active gel product is described consisting of a silica matrix which is amorphous to x-rays with uniform porosity, monomodal pore distribution and high surface area, within which one or more metal oxides possessing catalytic activity are dispersed. A process for preparing this catalytic gel is also described.