Patents Examined by Laura Bouchelle
  • Injection sensor with feedback mechanism
    Patent number: 10940273
    Abstract: The present disclosure provides devices for implanting tissue or other substances within the body. The devices can include a feedback mechanism, which can assist a surgeon in implanting the tissue or other substances by preventing excess shear force or pressure on the tissue or substance to be implanted.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: March 9, 2021
    Assignee: LifeCell Corporation
    Inventors: Aaron M. Barere, Evan J. Friedman
  • Hose line and method for producing same
    Patent number: 10933215
    Abstract: A hose line includes a sheath extending axially between a first hose end and a second hose end, and has an outer face and an inner face, an axial passage enclosed by the inner face and extending between the hose ends, a radial passage which extends through the sheath and connects the axial passage to the outer face, and a closure which is arranged between the radial passage and the second hose end and closes the axial passage in a fluid-tight manner. The radial passage is formed by a sheath portion which is bent and partially separated from the rest of the sheath along a partition line. The closure is formed by placing the sheath portion onto the inner face and connecting the sheath portion to the inner face in a fluid-tight manner. The hose line can be used in a catheter hose line.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 2, 2021
    Assignee: B. BRAUN MELSUNGEN AG
    Inventors: André Weiß, Oliver Kahlen
  • Means and method to give injections with little or no pain
    Patent number: 10933199
    Abstract: A preferred method to obtain a painless or near painless needle 8 penetration is disclosed to be in the following manner: Applying electric current using a TENS device in conjunction with physically stimulating the injection site at a frequency that is dependent on the frequency of the electric current applied to the injection site, followed by a needle 8 penetration into the skin 2.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: March 2, 2021
    Inventor: Pourang Bral
  • Injector
    Patent number: 10926033
    Abstract: An injector can include an ignition device having a partition member which forms a first space to store a gunpowder and which is formed of a prescribed rigid material such that the partition member is breached based on a rise in pressure of the first space when the gunpowder is burned. The injector can also include a case including a base section fixed on a side of the ignition device. The case can be arranged in a space inside the injector main body so as to cover the ignition device. The case can define a second space with the partition member of the ignition device and encapsulate, inside the second space, a combustion product of the gunpowder. When the gunpowder burns in the ignition device and pressure inside the second space rises, a part of the case extends so as to approach a prescribed end section.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: February 23, 2021
    Assignee: Daicel Corporation
    Inventor: Takaya Masumoto
  • Convertible plungers and methods for assembling the same in a medical barrel
    Patent number: 10918800
    Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and assembling them into syringes, e.g., pre-filled syringes.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: February 16, 2021
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Brian Russell Lilly, Kenneth Wade Kelly, Joseph W. Rogers, Jean-Pierre Giraud, Bruce Rabinne, Herve Pichot, Benjamin Hunt, Zachary Dean Freeman, Dalton Roe, Robert S. Abrams
  • In vivo gene therapy delivery procedure and device
    Patent number: 10918861
    Abstract: A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape of the gene vectors from the targeted tissue volume, such as would waste the vectors, promote undesired immune reactions, and/or incur prohibitive costs for the required dose of gene-containing virus vectors. In this regard, the invention provides a means to simultaneously achieve local electroporation and gene-containing vector injection in a portion of a vascularized organ. It includes two double-balloon catheters that create contained volumes in parallel blood vessels for the introduction of vectors with reduced loss along with electrodes providing electroporation of the cells in the same location where the vectors are injected.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: February 16, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Susan Hagness, Erik Aiken, John Booske, Hans Sollinger, Paul Laeseke, Tausif Alam
  • Transdermal administration device
    Patent number: 10918845
    Abstract: A transdermal administration device including a first administration member including a first substrate and a first projection protruding from a first administration surface of the first substrate, and a second administration member including a second substrate and a second projection protruding from a second administration surface of the second substrate. The first substrate has an aperture, and the second substrate is positioned within the aperture when viewed in a direction perpendicular to the second administration surface.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: February 16, 2021
    Assignee: TOPPAN PRINTING CO., LTD.
    Inventors: Hiroyuki Kato, Ichiro Takase
  • Caps for integrated fill and inject of safety needle devices
    Patent number: 10918801
    Abstract: Drug delivery safety devices comprise a safety needle device comprising a needle hub, a needle cannula, and a safety feature; and a cap comprising a cap body having a proximal end attached to the safety needle device and a distal end having an access opening that is in fluid communication with the needle cannula. The safety needle device allow for an integrated device for both filling and injection that do not interfere with passive safety features. The caps may have a fill feature that engages with a safety feature of the safety needle device to keep it in a fill state.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: February 16, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Ashley Rachel Rothenberg, Theodore Mosler, Laurie Sanders, Edward P. Browka, Peter Smith, Eli B. Nichols
  • Medical delivery device
    Patent number: 10918795
    Abstract: A medical delivery device is disclosed including a rod element, a dosage member and a lock mechanism. The rod element has a stem and the dosage member includes a delivery orifice and a chamber body. The stem of the rod element extends into the chamber body and the delivery orifice is arranged adjacent to a proximal end of the stem. In a dosing status, the rod element is movable along its longitudinal axis relative to the delivery orifice, wherein a dosage chamber is formed within the chamber body between the stem and the delivery orifice such that the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism is adapted to change the medical delivery device from a lock status to a dosing status, wherein, in the lock status moving the rod element along its longitudinal axis relative to the delivery orifice is prevented.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Medical delivery device
    Patent number: 10918794
    Abstract: A medical delivery device is disclosed having a rod element and a dosage member. The rod element has a stem and a first thread arrangement. The dosage member includes a delivery orifice, a chamber body and a second thread arrangement. The stem of the rod element extends within the chamber body and the delivery orifice is arranged adjacent to a proximal end of the stem. The dosage chamber is formed within the chamber body between the stem and the delivery orifice such that the dosage chamber increases when the rod element moves away from the delivery orifice. In a dosing status, the first thread arrangement of the rod element engages the second thread arrangement of the dosage member such that the rod element is moveable along its longitudinal axis relative to the delivery orifice of the dosage member.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Medical delivery device
    Patent number: 10918793
    Abstract: A medical delivery device is disclosed that includes a rod element, a dosage member and a lock mechanism. A stem of the rod element extends into an interior of a chamber body of the dosage member and a delivery orifice of the dosage member is arranged adjacent to a proximal end of the stem of the rod element. In a dosing status, the rod element is movable relative to the delivery orifice of the dosage member, such that a dosage chamber is formed within the chamber body between the stem of the rod element and the delivery orifice, wherein the dosage chamber increases when the rod element moves away from the delivery orifice. The lock mechanism changes the medical delivery device from a lock status to the dosing status, wherein in the lock status the rod element is prevented from moving relative to the dosage member delivery orifice.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 16, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Impacting type applicator for microneedle patch and leading end member
    Patent number: 10918846
    Abstract: To achieve stable administration of a medicine into a dermis by improving the operability of a device that inserts a microneedle into a skin. An impacting type applicator (1) for a microneedle patch is an applicator that applies a microneedle patch (3) to a skin includes a main body (5), a spring expanding/compressing lever (7), a resilient body (9), a lock mechanism (11), and a piercing switch (13). The spring expanding/compressing lever (7) is movably attached to the main body (5), and the microneedle patch (3) can be attached to a leading end of the spring expanding/compressing lever (7). The resilient body (9) is a member that imparts a biasing force to the spring expanding/compressing lever (7). The lock mechanism (11) is a mechanism that locks the spring expanding/compressing lever (7) in a state where the resilient body (9) exerts the biasing force on the main body (5).
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: February 16, 2021
    Assignee: Labo Juversa Co., Ltd.
    Inventors: Hiroyuki Nagai, Risa Nakaoka, Ichiro Ono, Kanji Takada
  • Drive mechanism for drug delivery pumps with integrated status indication
    Patent number: 10918788
    Abstract: A drive mechanism having integrated status indication includes a drive housing, a status switch interconnect, a drive biasing member, a piston, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the drive biasing member is configured to bear upon an interface surface of the piston. Drive mechanism may include an incremental status stem having a stem interconnect, wherein the stem resides within the drive housing and the piston, and wherein the stem has an interconnect which engages one or more contacts on the piston to provide incremental feedback. A drug delivery pump with integrated status indication includes a housing and an assembly platform, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection, a power and control system, and the drive mechanism having a drug container may be mounted.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: February 16, 2021
    Assignee: UNL HOLDINGS LLC
    Inventors: Sean M. O'Connor, Kevin Bokelman, Ian B. Hanson, Paul F. Bente, IV
  • Single use delivery device having a primer element
    Patent number: 10918809
    Abstract: A single use delivery device is disclosed having a manually deformable liquid container defining an inner chamber, the container having a distal end, a body, a proximal end, and an outlet on the distal end; a tip projecting from the outlet on the distal end of the container, the tip in fluid communication with the inner chamber of the container; and a primer element for removing one or more air bubbles from the chamber, said primer element being attached to and in fluid communication with the deformable container. A method of administering a fluid to or flushing a vascular access device using a single use pre-filled delivery device as described herein is also disclosed.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 16, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Suzanne Ferreri, Darrin Manke, James J. Kennedy, III, Morgan Carlson
  • Medical delivery device
    Patent number: 10912890
    Abstract: A medical delivery device is disclosed having a rod element with a stem and a first thread arrangement, a dial shell with a second thread arrangement, a delivery orifice, and a switching mechanism. In a dosing status, the rod element is movable relative to the delivery orifice by rotating the dial shell around the stem causing the first thread arrangement and the second thread arrangement to travel along each other, a dosage chamber is formed between the rod element and the delivery orifice when the rod element moves away from the delivery orifice, and the rod element is prevented from movement along a longitudinal axis when an axial force is applied. In a delivery status, the rod element is movable along the longitudinal axis relative to the delivery orifice when an axial force is applied and moving the rod element by rotating the dial shell around the stem is prevented.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: February 9, 2021
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Roberta Leah, Declan Reilly, Mark Digby Teucher, Paul Graham Hayton, Jonathan Paul Ridley, James Robert Coop
  • Multi-lumen indwelling catheter
    Patent number: 10905815
    Abstract: In one aspect, the present disclosure provides a catheter, the catheter with a distal length extending to a distal end, the distal length configured to indwell a cavity of a patient body. The distal length may include a first lumen extending longitudinally through a lengthwise portion of the distal length, where the first lumen may be at least partially defined by a first inner diameter surface of the distal length. The distal length may include a second lumen extending longitudinally through the lengthwise portion of the distal length, where the second lumen may be at least partially defined by a second inner diameter surface of the distal length. A first fenestration may be disposed through a side wall of the first lumen. A proximal length of the catheter may include a proximal lengthwise portion of the first lumen and the second lumen.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: February 2, 2021
    Assignee: CAREFUSION 2200, INC.
    Inventors: Palak Doshi, Shayna Massi, John A. Krueger
  • Auto-injectors featuring medicine delivery assurance
    Patent number: 10898655
    Abstract: Auto-injectors can deliver many different types of medicines into people. One failure mode of auto-injectors is failing to insert the needle into the patient while the medicine is propelled from the auto-injector. This error results in the medicine not entering the patient's body. An auto-injector can include a syringe and probes to prevent medicine from being propelled if the person administering the injection does not position the auto-injector correctly.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: January 26, 2021
    Inventor: Benson Eric Wengreen
  • Urinary catheter having a conical proximal section
    Patent number: 10898676
    Abstract: A urinary catheter has a tube having a proximal section that is insertable into a urethra and a distal section having a connector secured to a distal end of the tube. A lumen is formed longitudinally in the tube and a hydrophilic coating applied to an exterior surface of the tube. The proximal section of the tube includes a proximal tip end that is closed to terminate the lumen at the proximal tip end, with the proximal tip end rounded for insertion of the proximal tip end through the urethra and into a bladder. The proximal section of the tube is conical such that a first outer diameter of the proximal section of the tube measured at the proximal tip end is smaller than a second outer diameter of the proximal section of the tube measured distal from the proximal tip end.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: January 26, 2021
    Assignee: Coloplast A/S
    Inventors: Egon Triel, Johnny Wagner
  • Vascular access port systems and methods
    Patent number: 10894120
    Abstract: In certain systems disclosed herein, one or more of a first vascular access port and a second vascular access port can be selected by a customer. Each of the first and second vascular access ports can be implanted subcutaneously within a patient, and each can include a base configured to be attached to a vessel, a body that extends away from the base, and a guidance passageway that extends through the body and the base and includes a funnel region. A maximum height defined by the base and body of the second vascular access port can be greater than a maximum height defined by the base and body of the first vascular access port.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: January 19, 2021
    Assignee: Advent Access Pte. Ltd.
    Inventors: Nathaniel P. Young, G. Doug Smith, Mark A. Crawford
  • Steerable catheter system with hub
    Patent number: 10894145
    Abstract: A steerable catheter having a hub with a control feature includes a semi-rigid catheter with the hub attached at the proximal end. The distal end of the catheter includes a distal tip and a flexible portion adjacent the distal tip. The catheter includes a working channel, and further includes a channel through which a tension member or wire extends to the distal tip. Tension in the wire causes the distal tip to deflect and be steered. The hub includes a fixed member attached to the catheter, an inner member that moves axially relative to the fixed member, and an outer member that rotates relative to the inner member and the fixed member. Rotation of the outer member results in translation of the inner member, which is attached to the tension member and provides for controlled steering of the distal tip.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: January 19, 2021
    Assignee: Cook Medical Technologies LLC
    Inventors: Jeffry Scott Melsheimer, Patrick James Zito