Patents Examined by Laura Lutz
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Patent number: 5804686Abstract: The present invention encompasses structures of the formula I: ##STR1## or the pharmaceutically acceptable non-toxic salts thereof wherein: G represents ##STR2## where Q is aryl substituents optionally mono or disubstituted with hydroxy or halogen;T is halogen, hydrogen, hydroxyl, amino or alkoxy having 1-6 carbon atoms;W is oxygen, nitrogen, sulfur, or optionally substituted methylene;X is hydrogen, hydroxyl, or alkyl;Z is an organic or inorganic substituent optionally forming a ring with subtituents on Q; ##STR3## independently represent optionally substituted carbon chains; wherein k, m, and n are independently 0, or an integer of from 1-3 R.sub.3, R.sub.4, R.sub.5, and R.sub.6 are the same or different and represent organic or inorganic substituents.These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors.Type: GrantFiled: January 19, 1996Date of Patent: September 8, 1998Assignee: Neurogen CorporationInventors: Pamela Albaugh, Gang Liu, Kenneth Shaw, Alan Hutchison
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Method and apparatus for direct oxygen injection with a reactant stream into a fluidized bed reactor
Patent number: 5801265Abstract: A system provides an oxygen-bearing gas and a gaseous reactant stream to a fluidized bed reactor. A sparger causes an entraining of the oxygen bearing gas into the reactant gas stream. A feed line couples the sparger to the reactor's fluidized bed and introduces the reactant gas stream and entrained oxygen-bearing gas directly into contact with the fluidized bed. A controller controls both the amount of oxygen-bearing gas and the gaseous reactant so that, at the point of feed injection, the fluidized bed catalyst does not experience an oxygen deficiency. To assure safety, the reactant content of the combined feed and oxygen stream is maintained above an upper flammability limit, preferably with a safety margin of at least 25%. In one embodiment, the system enables the production of acrylonitriles from a feed stream comprising ammonia, propylene and oxygen.Type: GrantFiled: August 24, 1995Date of Patent: September 1, 1998Assignee: Praxair Technology, Inc.Inventors: Matthew Lincoln Wagner, Thomas John Bergman, Jr. -
Patent number: 5723641Abstract: Processes for hydrocyanation of nonconjugated acyclic aliphatic monoolefins, monoolefins conjugated to an ester group, or monoolefins conjugated to a nitrile group which utilize a catalyst precursor composition comprising a bidentate phosphite ligand and zero-valent nickel preferably in the presence of a Lewis acid promoter. Catalyst precursor compositions are also disclosed.Type: GrantFiled: September 26, 1996Date of Patent: March 3, 1998Assignee: E. I. du Pont de Nemours and CompanyInventors: Wilson Tam, Kristina Ann Kreutzer, Ronald James McKinney
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Patent number: 5716906Abstract: Saccharin derivatives of the formula I ##STR1## where the substituents have the following meanings: L and M are hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, chlorine, cyano, methylsulfonyl, nitro or trifluoromethyl;Z is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.5 -alkynyl, C.sub.1 -C.sub.4 -acyl, benzyl or phenyl, the phenyl rings in each case being unsubstituted or substituted by halogen or C.sub.1 -C.sub.4 -alkyl;Q is a radical T-J, whereT is a carbonyl radical CO or the radical --CHY,J is a 4-linked isoxazole ring of the formula II ##STR2## where R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl andR.sup.2 is C.sub.1 -C.sub.4 -alkyl, cyclopropyl, 1-methylcyclopropyl or 1-methylthiocyclopropyl;Y is an OH group, a hydroxyl group which may be acylated by C.sub.2 -C.sub.4 -acyl or a chlorine atom;and agriculturally customary salts of the compounds I are described.Type: GrantFiled: February 10, 1997Date of Patent: February 10, 1998Assignee: BASF AktiengesellschaftInventors: Peter Plath, Wolfgang von Deyn, Stefan Engel, Uwe Kardorff, Hartmann Konig, Harald Rang, Matthias Gerber, Helmut Walter, Karl-Otto Westphalen
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Patent number: 5716905Abstract: Saccharin derivatives of the formula I ##STR1## where the substituents have the following meanings: L and M are hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -alkylthio, chlorine, cyano, methylsulfonyl, nitro or trifluoromethyl;Z is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.3 -C.sub.8 -cycloalkyl, C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.5 -alkynyl, C.sub.1 -C.sub.4 -acyl, benzyl or phenyl, the phenyl rings being unsubstituted or substituted by halogen or C.sub.1 -C.sub.4 -alkyl;R.sup.1 is cyclopropyl, 1-methylcyclopropyl, 1-methylthiocyclopropyl or tert-butyl;and agriculturally customary salts of the compounds I are described.Type: GrantFiled: February 3, 1997Date of Patent: February 10, 1998Assignee: BASF AktiengesellschaftInventors: Peter Plath, Wolfgang von Deyn, Stefan Engel, Uwe Kardorff, Christoph Nubling, Hartmann Konig, Harald Rang, Matthias Gerber, Helmut Walter, Karl-Otto Westphalen
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Patent number: 5710281Abstract: Organic compounds having at least one ethylenically-unsaturated group are described, the organic compounds being suitable for use in coatable compositions as reactive diluents; compounds of the invention preferably have a divalent organic linking moiety devoid of reactive groups other than optional ethylenically-unsaturated groups, and a polar organic moiety and are particularly adept in solubilizing aminoplast resins having radiation-curable pendant groups.Type: GrantFiled: February 23, 1996Date of Patent: January 20, 1998Assignee: Minnesota Mining and Manufacturing CompanyInventors: Ernest L. Thurber, Eric G. Larson, Alan R. Kirk, Gregg D. Dahlke
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Patent number: 5708188Abstract: The invention relates to mixed crystals of 1,4-diketopyrrolo?3,4-c!pyrroles, consisting of 1 mol each of two different compounds of formulae ##STR1## as well as single-phase solid solutions of two different compounds of formulae I and II, wherein the diketopyrrolopyrrole having the smaller geometrical constitution is present in an amount of 53 to 70 mol %. A and B are as defined in claim 1. The novel mixed crystals as well as the novel solid solutions are admirably suited for pigmenting organic material of high molecular weight.Type: GrantFiled: September 28, 1995Date of Patent: January 13, 1998Assignee: Ciba Specialty Chemicals CorporationInventors: Zhimin Hao, Abul Iqbal, Bernhard Medinger, Olof Wallquist
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Patent number: 5705456Abstract: Compounds of formula I: ##STR1## where n is 0 or an integer from 1 to 5; X is halogen, nitro or cyano, or C.sub.1-10 hydrocarbyl or C.sub.1-10 hydrocarbyloxy, either of which may be substituted with one or more halogen atoms;Y is CH.sub.2, O or S; andR.sup.1 and R.sup.2 independently represent hydrogen, C.sub.1-6 alkyl, C.sub.1-6 haloalkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl or halogen;Processes for the preparation of compounds of formula I, herbicidal compositions and methods utilising them are also disclosed.Type: GrantFiled: November 29, 1996Date of Patent: January 6, 1998Assignee: Zeneca LimitedInventors: Glynn Mitchell, Stephen Christopher Smith