Patents Examined by Leon Blaine Lankford
  • Patent number: 8337834
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: December 25, 2012
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick
  • Patent number: 7189568
    Abstract: The present invention provides a method of clonal propagation of Pandanus amaryllifolius and further provides a composition for the clonal propagation of scented Pandanus amaryllifolius.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: March 13, 2007
    Assignee: Council of Scientific and Industrial Research
    Inventors: Bhagyalakshmi Neelwarne, Thimmaraju Rudrappa, Mandayam Singara Narayan, Gokare Aswathanarayana Ravishankar
  • Patent number: 7186555
    Abstract: The present invention provides methods and pharmaceutical compositions of the human glycoprotein fetuin, or ?2-HS glycoprotein, or fragments thereof to mitigate tissue damage associated with ischemia, particularly in stroke or in myocardial infarction.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: March 6, 2007
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Kevin J. Tracey, Haichao Wang
  • Patent number: 7176023
    Abstract: A method is described to induce primate embryonic stem cells to differentiate into a relatively homogenous population of endothelial cells. The ES derived endothelial cells have the general morphological and cell surface marker characteristics of endothelial cells. The ES derived endothelial cells also are capable of inducing and participating in blood vessel formation (or vascularization) when transplanted into tissue in vivo.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: February 13, 2007
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Dan S. Kaufman, Rachel Lewis, Robert Auerbach
  • Patent number: 7175842
    Abstract: The invention features methods of promoting hair growth in a subject. The methods include inducing or mimicking the effects of Wnt promoted signal transduction, e.g., by increasing the level of Wnt protein or administering an agent which mimics an effect of Wnt promoted signal transduction, e.g., by administering lithium chloride. Methods of inhibiting hair growth are also provided.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: February 13, 2007
    Assignee: The General Hospital Corporation
    Inventors: Bruce A. Morgan, Jiro Kishimoto, Robert Burgeson
  • Patent number: 7169607
    Abstract: The invention features a liver cell culture comprising hepatocytes that have increased detoxification enzyme activity when isolated from a liver of a donor that had been administered at least one induction agent prior isolation of hepatocyte cells. The induced hepatocytes are used in a bioreactor and cultured to produce hepatocyte cell products or metabolize toxins added to the culture. The bioreactor is, or is an integral part of, a liver assist device used to treat a patient in need of liver assist.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: January 30, 2007
    Assignee: Organogenesis, Inc
    Inventors: Susan J. Sullivan, Paul G. Gregory, Paul A. DiMilla
  • Patent number: 7157082
    Abstract: The present invention relates to methods and compositions related to the use of enzymes of the allene oxide synthase family for reducing myocardial ischemia reperfusion injury associated with myocardial infarction, thrombolysis, angioplasty and coronary bypass surgery. The methods of the invention comprise administration of allene oxide synthases, which are capable of eliminating lipid hydroperoxides, as a potent cardioprotective agent. The invention is based on the discovery that administration of allene oxide synthase following severe global ischemia stimulates cardiac recovery.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: January 2, 2007
    Assignee: Arizona Board of Regents
    Inventor: Ralph A. Backhaus
  • Patent number: 6797508
    Abstract: The invention relates to bioreactor for fermenting solid substrates, comprising a fermentation vessel (2), a device for feeding bioreactive substances and a nozzle arrangement in the fermentation vessel (2). The invention is characterized in that a nozzle arrangement (10, 20) consisting of a plurality of pipes (14, 24) which project into the reaction chamber (49) of the fermentation vessel (2) in parallel and which are provided with nozzles (16, 28) is situated in the fermentation vessel (2). The invention also relates to a method for aerobically fermenting solids. A reaction medium containing these solids is mixed using a compressed gas (48) which is guided into the reaction mixture from above.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: September 28, 2004
    Assignee: Hofer Bioreact GmbH
    Inventor: Udo Hölker
  • Patent number: 5387109
    Abstract: Disclosed are a novel fructosylamine deglycase characterized by the specificity to amadori compounds of catalyzing oxidation of the compounds to produce an .alpha.-ketoaldehyde, an amine derivative and hydrogen peroxide; a method of producing the novel enzyme by cultivating microorganisms belonging to the genus Candida and having an ability of producing the novel enzyme; and a method of quantitative determination of amadori compounds by applying the novel enzyme to a sample containing amadori compounds to measure the amount of the hydrogen peroxide to be formed by the oxidation reaction or measure the amount of the oxygen to be consumed by the reaction to thereby obtain the amount of the amadori compounds from the measured value. The invention provides a novel enzyme characterized by the high specificity to the reaction with amadori compounds, especially that having therein a saccharide moiety as bonded to the .epsilon.
    Type: Grant
    Filed: May 24, 1993
    Date of Patent: February 7, 1995
    Assignee: Nakano Vinegar Co., Ltd.
    Inventors: Atsushi Ishikawa, Yoshifumi Ohshima, Mikio Yamada, Hajime Okumura, Yoshiya Kawamura