Patents Examined by Lia Feisee
  • Antibodies with altered effector functions
    Patent number: 5624821
    Abstract: An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 29, 1997
    Assignee: Scotgen Biopharmaceuticals Incorporated
    Inventors: Gregory P. Winter, Alexander R. Duncan, Dennis R. Burton