Abstract: Infusions of brain-derived neurotrophic factor, neurotrophin-3 or neurotrophin-4 are used to produce analgesia in mammals. In addition, these neurotrophins are used to treat other diseases or disorders mediated by serotonin.
Type:
Grant
Filed:
January 25, 1995
Date of Patent:
October 27, 1998
Assignee:
Regeneron Pharmaceuticals, Inc.
Inventors:
Judith Siuciak, Charles A. Altar, Ronald M. Lindsay