Abstract: There are disclosed therapeutic microcapsules for beneficial insects having a non-toxic matrix with a medicament for treating a beneficial insect disorder substantially uniformly distributed therethrough and therapeutic compositions in which the microcapsules are in a carrier. Also disclosed is the method of treating beneficial insect disorders with such microcapsules and compositions.
Type:
Grant
Filed:
November 20, 1996
Date of Patent:
December 25, 2001
Assignee:
Enviroquest, Ltd
Inventors:
Sherrene D. Kevan, Peter G. Kevan, Jack D. Trevino
Abstract: Use of a cellulose ester for reducing the drying time of a nail varnish, wherein the nail varnish comprises, in a solvent medium, nitrocellulose a dyestuff, the cellulose ester being present in a synergistic amount, relative to the amount of nitrocellulose, effective for reducing the drying time of the nail varnish.
Abstract: A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The poorly crystalline apatitic calcium phosphate is characterized in that, when placed in an intramuscular or subcutaneous site, resorption of at least 1 g of the material is complete within one year. The supplementary material is in intimate contact with the hydroxyapatite material in an amount effective to impart a selected characteristic to the composite. The supplemental material may be biocompatible, bioresorbable or non-resorbable.
Type:
Grant
Filed:
March 2, 1998
Date of Patent:
December 18, 2001
Assignee:
Etex Corporation
Inventors:
Dosuk D. Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi
Abstract: Controlled release devices are disclosed which are biocompatible and can be implanted into the eye. The devices have a core comprising a drug and a polymeric outer layer which is substantially impermeable to the entrance of an environmental fluid and substantially impermeable to the release of the drug during a delivery period, and drug release is effected through an orifice in the outer layer. These devices have an orifice area of less than 10% of the total surface area of the device and can be used to deliver a variety of drugs with varying degrees of solubility and or molecular weight. Methods are also provided for using these drug delivery devices.
Type:
Grant
Filed:
October 22, 1999
Date of Patent:
December 18, 2001
Assignee:
Oculex Pharmaceticals, Inc.
Inventors:
Vernon G. Wong, Mae W. L. Hu, Donald E. Berger, Jr.
Abstract: Bioactive, degradable composite material and composite material microspheres were produced using a new solid-in-oil-in-water method. Compositions and methods for tissue engineering and drug delivery are provided.
Type:
Grant
Filed:
November 12, 1999
Date of Patent:
December 11, 2001
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Paul Ducheyne, Portonovo S. Ayyaswamy, Qing-Qing Qiu
Abstract: The present invention relates to the use of bicozamycins for the prophylaxis and treatment of infections with a verotoxin-producing E. coli, as well as for eradicating verotoxin-producing E. coli in livestock.
Abstract: A dispenser for a volatile aromatic substance is provided which includes a closed container formed from a single blank of folded sheet material in which the aromatic substance is deposited. The blank is folded to form a plurality of coacting interior and exterior walls, one of the walls having a tab form which is broken along a line of weakness to expose at least one vent passage in an underlying interior wall through which the vapors of the aromatic substance may pass. The tab form is hingedly connected to the blank so that it will not be removed therefrom and in one embodiment, coacts with a vent passage so that the tab form is displaced from underlying interior walls to modulate the circulation of vapors flowing from the vent passages. A hermetic coating is provided to preserve the shelf life of the container, including the aromatic substance deposited therein.
Type:
Grant
Filed:
May 15, 2000
Date of Patent:
December 11, 2001
Assignee:
Scientific Mfg. Co., Inc.
Inventors:
Howard Alboum, John Williams, Ruggiero Abbatemarco
Abstract: A simulated capsule-like medicament comprising a subcoating of a mixture of a water-soluble, film-forming polymer, e.g. hydroxypropylmethyl cellulose and a hydrophobic plasticizer, e.g. castor oil, which promotes a smooth uniform and substantially bubble free outer coating, e.g. gelatin, for the capsule-like medicament; capsule-like medicaments which are slightly bowed in shape; and a process of making such medicaments.
Type:
Grant
Filed:
January 14, 2000
Date of Patent:
December 4, 2001
Assignee:
McNeil-PPC, Inc.
Inventors:
Kishor B. Parekh, Dennis C. Wieand, Jean B. Leasure
Abstract: A method for making, storing and using a surgical graft from human amniotic membrane; the resulting graft; and the storage solution. The amniotic membrane is obtained from human placenta, from which the chorion has been separated. Sheets of the amniotic membrane are cut to size and mounted on filter paper. The cells of the amniotic membrane are killed, preferably while being frozen and thawed in the storage solution. The storage solution comprises a culture medium and a hyperosmotic agent, wherein the hydration of the amniotic membrane is maintained. The membrane can be impregnated with therapeutic agents, prior to storage, for use in post surgical healing or other therapies.
Abstract: A copolymer having silyl groups with at least one reactive functional group bonded thereto. The copolymer comprises a monomer (A) shown by the following Formula (I):
wherein R1 is hydrogen atom or methyl; R2 is alkylene group having 1-6 carbon atoms; and R3, R4 and R5 each is a reactive functional group which can cross-link molecules of the copolymer by hydrolyzing. Further, the copolymer preferably comprises, as a constituent monomer, an alkyl (meth)acrylate and a siloxane-containing (meth)acrylate. A coating-forming method comprises hydrolyzing the composition on a material to be treated to cross-link molecules of the copolymer when on the material. A coating of the cross-linked copolymer has resistance to washing. This coating can modify the nature of hair, improve make-up retention, and provide skin-protecting. It can impart water-repellency, resistance to fouling, suitability as a sizing and crease resistance to fibers.
Abstract: Implantable medical devices and drug delivery implants containing polyarylate random block copolymers are disclosed, along with methods for drug delivery and for preventing the formation of adhesions between injured tissues employing the polyarylate random block copolymers.
Abstract: The present invention relates to the formation of microparticles from copolymers during a process involving precipitation with compressed antisolvents. The family of suitable copolymers have a semi-crystalline structure that above their glass transition temperature retain sufficient crystalline strength to form microparticles. The invention also provides systems comprising the microparticles encapsulated with a desired compound for the controlled release of the compound over a predetermined period of time.
Type:
Grant
Filed:
February 9, 2000
Date of Patent:
November 20, 2001
Assignee:
University Technology Corporation
Inventors:
Theodore W. Randolph, Corinne Lengsfeld, Richard Frank Falk, III
Abstract: A cosmetic composition having particulates coated with fluorosilane, such as a pigment and/or filler coated with fluorosilane is provided. The cosmetic composition can be a blush, a concealer, an eye shadow, a lipstick, a liquid make-up, a mascara, a moisturizer, or a powder. The present invention also provides methods of (a) reducing staining potential of a lipstick on a person, (b) improving water and/or oil resistance in cosmetic compositions, especially in a mascara, (c) reducing oil breakthrough in a facial product, and (d) reducing color drift in a powder cosmetic during wear.
Abstract: The invention concerns a pharmaceutical and/or food composition comprising a suitable pharmaceutical and/or food vehicle and a heat shock protein and at least conformation or sequential epitopes of an antigenic structure inducing a graft versus host, an allergic or autoimmune reaction.
Abstract: A method of treating or preventing recurrence of warts including a step of administering to a patient an anti-inflammatory drug, particularly, ciprofloxacin.
Abstract: A composition for conditioning the skin and for treating pseudofolliculitis barbae. Also disclosed is a method for making said composition. The composition is comprised of water, Aloe Vera juice, ammonium alum, glycerine, and ethanol. It can be made using relatively unsophisticated processing equipment. The process essentially comprises adding Aloe Vera juice to water, heating the water almost to its boiling point, adding glycerine and ammonium alum, allowing the mixture to cool, and adding a small amount of ethanol to avoid precipitation of the ammonium alum during prolonged storage.
Abstract: This invention is a method for reduction of hair loss and stimulation of hair growth on the scalp of a human patient. The method comprises the step of administering a presynaptic neurotoxin into the scalp of the patient in a quantity and concentration to provide a therapeutically-effective flaccid paralysis of the muscle tissue outside of the skull of the patient. The result is a reduction in tissue tension in the desired area of hair-growth without affecting any tissue not outside the skull of the patient.
Abstract: The present invention is concerned with solid dosage forms comprising a) valsartan and optionally HCTZ, and b) pharmaceutically acceptable additives suitable for the preparation of solid oral dosage forms by compression methods.
Type:
Grant
Filed:
May 7, 1999
Date of Patent:
September 25, 2001
Assignee:
Novartis AG
Inventors:
Robert Frank Wagner, Yoshimitsu Katakuse, Takashi Taike, Fujiki Yamato, Manfred Kohlmeyer
Abstract: This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at least one natural or synthetic polycarboxylated polymer and at least one polysaccharide; drying the solution to form a solid; and heat treating the solid to effect cross-linking and to form the bioadhesive composition.
Type:
Grant
Filed:
February 11, 2000
Date of Patent:
September 4, 2001
Assignee:
National Starch and Chemical Company Investment Holding
Corporation
Inventors:
Paul B. Foreman, Paul Richardson, John Tsai, Jean Paul Remon, Jody Voorspoels, Dieter Ameye, Catherine Callens