Abstract: The plasma sensor monitors parameters characterizing the condition of the plasma during the treatment phase and/or the change thereof in order to recognize a prefiguring or already occurred interruption of the plasma in this manner and to avoid this interruption and, in the ideal case, avoid this by already changing the voltage form previously. The mentioned mechanisms can be used by the control device (22) also during a pulse packet. The length of each pulse packet is adapted at each change of the voltage form according to their characteristics in order to guarantee a constant average power.

Abstract: A lung function analysis system includes motion sensing devices each including accelerometers, gyros, battery, processor, and ireless transmitter, the processor configured to read motion data from the accelerometers and gyros and transmit the motion data over the wireless transmitter. The system includes a data collection device receiving the motion data and recording the motion data in a database; and a computing device with a lung function data analysis routine adapted to analyze the motion data to provide information useful in treating pulmonary disease. In embodiments, the lung function analysis routine includes a classifier trained on a database of motion data and diagnoses. In embodiments, the accelerometers and gyros are three-axis and/or the devices include electromyographic sensors. In embodiments, the system includes remote sensors such as a stereo camera with or without markers, millimeter-wave radar, or an ultrasonic echolocation device.

Abstract: An assembly for performing an electrosurgical procedure. A cannula includes a cannula hub defining a middle bore having a smaller diameter than a proximal bore. An electrode includes an electrode head having an outer diameter smaller than the proximal bore and greater than the middle bore. A syringe includes a syringe head having a length sufficient to extend past the proximal bore, and an outer diameter sized to engage the middle bore to form an annular seal at an interface between the syringe and the cannula. A step may define a transition surface between the proximal bore and the middle bore, and at least one notch may be within the step to maintain fluid communication between the middle bore and the proximal bore when the electrode head is engaging the step. The cannula head may include first and second locking features configured to engage the syringe and electrode, respectively.

Abstract: Surgical devices and related methods are disclosed. An example end effector for a surgical device may include a first jaw, a second jaw, and an articulating mechanism operable to move the first jaw between an open position, an intermediate position, and a closed position. An example articulating mechanism may include a first jaw mount coupled to the first jaw so that movement of the first jaw mount along a path causes rotation and translation of the first jaw mount and the first jaw. A pivotably mounted crank may operably couple an actuator linkage to the first jaw mount so that moving the actuator linkage rotates the crank, and rotation of the crank may move the first jaw mount along the path.

Abstract: An energy delivery system for performing tissue ablation at the distal end of an Electromagnetic Navigation Bronchoscopy (ENB) instrument. The system is insertable through an instrument channel of a steerable instrument cord in an ENB instrument, and comprise a coaxial cable with a radiating tip portion. The tip portion comprises a first conductive element electrically connected to the coaxial cable's inner conductor and a second conductive element electrically isolated from the inner conductor. The conductive elements are arranged to act as: an active electrode and a return electrode for delivering the RF energy into tissue surrounding the radiating tip portion, and an antenna for radiating the microwave energy as a localized microwave field. The system may be arranged to delivery energy according to a predetermined profile comprising interleaving periods of RF and microwave energy or a combination thereof, or a dynamic profile based on detected tissue impedance.

Abstract: A treatment system includes an energy treatment tool and a power supply device. The energy treatment tool includes respective first and second grasps configured to be coupled with one another and are capable of pivoting with respect to one another so as to grip a treatment target therebetween. A plurality of bipolar electrodes is attached to the respective first and second grasps. The plurality of bipolar electrodes receives a high-frequency current to flow through the treatment target so as to develop a first temperature distribution in the treatment target. A treatment energy source is configured to be coupled to one of the respective first and second grasps and receives electric energy to generate treatment energy different from the high-frequency current and to apply the generated treatment energy to the treatment target so as to develop a second temperature distribution in the treatment target.

Abstract: A wearable electronic device and method are disclosed, including: at least one sensor including a plurality of electrodes, at least one processor operatively connected with the at least one sensor, and a memory operatively connected with the at least one processor. The processor implements the method, including detecting coupling of the wearable electronic device with an external accessory contacting a body of a user, and based on detecting the coupling with the external accessory, measuring a biometric signal using a voltage received from at least two electrodes from among a plurality of measurement electrodes included in the external accessory.

Abstract: A method of treating or preventing acute respiratory distress syndromes (ARDS) includes advancing a cryogenic treatment element into a target bronchus of a mammal and exchanging cryogenic energy between the target bronchus and the cryogenic treatment element for a predetermined period of time until a target temperature of the target bronchus is reached to cause neuropraxia of nerves within the target bronchus.

Abstract: The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

Abstract: Low power MASER (Microwave Amplification by Stimulated Emission of Radiation) radiation is used to non-invasively record molecular activity in a biological object such as a brain. Low power MASER radiation is also used to neuromodulate molecular targets via Rabi coupling, resulting for example in conformational and function change in specific molecular targets such as ligand-gated ion channels, voltage-gated ion channels, G-proteins, or dopamine receptors. The method can be used to change the energy state of targeted molecules via energization or enervation, or to ablate targeted molecules.

Abstract: A method includes receiving position signals that are indicative of positions of multiple electrodes disposed on an expandable balloon that is fitted at a distal end of a shaft for engaging a lumen of an organ to occlude the lumen. Based on the received position signals, a change is calculated in one or more dimensions of the balloon between (i) a first configuration in which the balloon is inflated but not engaged in the lumen, and (ii) a second configuration in which the balloon is inflated and engaged in the lumen. Using the calculated change, a degree is estimated to which the balloon occludes the lumen. The estimated degree of occlusion is presented to a user.

Abstract: An electrically conductive irrigation fluid for use in bipolar resectoscopic surgery, wherein the irrigation fluid being brought into contact with the electrode of a resectoscope and tissue being coagulated and/or resected by means of the electrode surrounded by the irrigation fluid, wherein the irrigation fluid includes metal ions. Moreover, the method relates to a resectoscopy system including a resectoscope and an irrigation system that is connected to the resectoscope, the resectoscope having a handle and a tubular shaft, and the shaft including an electrode instrument that is arranged so as to be longitudinally displaceable and has in its distal end region an electrode to which high-frequency current can be applied, wherein the irrigation system includes an irrigation fluid, which can be conducted through the shaft of the resectoscope to the electrode.

Abstract: A micro-sized cold atmospheric plasma accessory. The micro-sized cold atmospheric plasma accessory comprises a tube, an active electrode within said tube, and a nozzle at a distal end of said tube, said nozzle having an inner diameter less than 1 mm and a length less than 30 mm. A distal end inner diameter of said tube is greater than said inner diameter of said nozzle. The nozzle preferable is 15-25 mm in length. The nozzle may comprise stainless steel. The tube may have an inner diameter greater than 1 mm. The nozzle preferably has a distal end inner diameter less than 280 ?m. The micro-sized cold atmospheric plasma accessory may further comprise a return electrode on an outside of said tube.

Abstract: Disclosed herein are systems, devices, and methods for treating heart failure. In some variations, a catheter for forming an anastomosis in a heart may comprise a first catheter comprising an electrode. A second catheter may be slidably disposed within the first catheter. The second catheter may comprise a barb and a dilator comprising a mating surface configured to engage the electrode.

Abstract: This disclosure describes the methods, devices, and systems of treating diseased tissue with integrated nanosecond pulse irreversible electroporation. Methods and systems as disclosed provide MRI compatible shielded electrodes and electrode leads to prevent emanating radiofrequency noise and improve image quality, disconnecting the electrode from the cable linkage to the pulse generator reduce electromagnetic interference and image artifacts, placing electrodes strategically within a guide cannula to minimize distortion from heterogeneities or maximize ablation within the tissue, utilizing conductive fluids, innate or external, such as cerebral spinal fluid or grounding pads to provide a pathway for current return, and for timing of the electrical waveforms with inherent brain electrical activity.

Abstract: Systems, methods, and devices allow intravascular or percutaneous mapping, orientation and/or ablation, in bodily cavities or lumens. A device includes elongate members, moveable between an unexpanded configuration and an expanded or fanned configuration. The elongate members form a stack in the unexpanded configuration to fit through a catheter sheath. The elongate members follow respective arcuate or curvilinear paths as advanced from the sheath into the bent or coiled stack configuration, adopting volute, scroll or rho shapes, and may be nested. The elongated members are fanned or radially spaced circumferentially with respect to one another into the expanded or fanned configuration. Transducer elements carried by elongate members sense various physiological characteristics of or proximate tissue, and/or may apply energy to or proximate tissue. The elongate members are rotatable in groups or as a group in the expanded configuration. The device is retractable.

Abstract: An electrosurgical apparatus is provided including a housing, a flexible shaft, and a distal tip. The housing may further be coupled to an electrosurgical generator and gas supply. The distal tip of the electrosurgical apparatus may be grasped by a grasping tool, such that the orientation and position of the distal tip relative to the housing may be manipulated to achieve a plurality of positions. The electrosurgical apparatus provides electrosurgical energy and inert gas to an electrode within the distal tip of the electrosurgical apparatus to generate a plasma beam. In one aspect, the electrode is a retractable blade such that the electrosurgical apparatus can be used for mechanical and electrosurgical cutting during surgery when the electrode is in an extended position and for cold plasma applications during surgery when the electrode is in a retracted position.

Abstract: Systems, methods, and devices allow intravascular or percutaneous mapping, orientation and/or ablation, in bodily cavities or lumens. A device includes elongate members, moveable between an unexpanded configuration and an expanded or fanned configuration. The elongate members form a stack in the unexpanded configuration to fit through a catheter sheath. The elongate members follow respective arcuate or curvilinear paths as advanced from the sheath into the bent or coiled stack configuration, adopting volute, scroll or rho shapes, and may be nested. The elongated members are fanned or radially spaced circumferentially with respect to one another into the expanded or fanned configuration. Transducer elements carried by elongate members sense various physiological characteristics of or proximate tissue, and/or may apply energy to or proximate tissue. The elongate members are rotatable in groups or as a group in the expanded configuration. The device is retractable.

Abstract: The disclosure relates to a nozzle for a device for the dermo-cosmetic treatment of dark skin spots by cyto-selective cryotherapy comprising a spray jet supplied by a tank of pressurised liquified cryogenic gas. The nozzle comprises an upper ring for connecting to a shell, extended by a central body of which the side wall which narrows downwards has longitudinal openings and delimits a gas expansion chamber communicating with a frustoconical dispersal conduit arranged inside an end piece to be applied to the skin and opening to the outside through a discharge port.

Abstract: A cryosurgical instrument includes a feed line for conveying fluid into an expansion chamber. The feed line has a capillary line section that terminates in the expansion chamber and forms an aperture for the fluid to undergo the Joule-Thomson effect. The flow cross-section of the feed line decreases in at least one transition section of the feed line in the form of a funnel. Following each transition section there preferably follows a step section, in which latter section the flow cross-section is preferably largely constant. The last step section is preferably formed by the capillary line section. Due to the acceleration of the fluid in the transition sections and the abating of pressure fluctuations in the capillary tube section and, optionally in the additional step sections, the expansion range in the expansion chamber is increased, without impeding the backflow of the expanded gas out of the expansion chamber.