Abstract: A diaper changing restraint system for restraining an infant while changing the infant's diaper. The system provides a four-point restraint system for securing the infant by itself or in conjunction with a diaper-changing table. The system includes a bottom portion, a top portion and a mechanism for fastening the top portion to the bottom portion. The top portion is generally one piece and is in the shape of the front of a tank-top shirt having two shoulder straps and two side portions. The bottom portion includes a stiff stable surface having four cloth-like material portions attached thereto. The four cloth-like material portions are positioned so as to align with the two shoulder straps and the two side portions of the top portion. A fastening mechanism, preferably hook and pile (i.e., VELCRO.RTM.), is provided for attaching the top portion to the bottom portion via the two shoulder straps and the two side portions.