Abstract: In at least a medical system including a structure, a plurality of transducers located on the structure, a shaft member configured to percutaneously deliver the structure to a location within a patient, a plurality of conductors at least partially within the shaft member and coupled to the transducers, and a controller operatively coupled to the transducers via the conductors, the controller may cause first electrical power to be delivered to one or more of the transducers for a first period of time, where second electrical power less than the first electrical power, if delivered for a second period of time longer than the first period time would result in a steady-state temperature of a portion of the shaft member that would be just below a safe temperature limit for at least the portion of the shaft member.

Abstract: Methods and systems for ablating target tissue, such as in or along an airway, include modulation one of power and current of an a system to achieve a treatment output or parameter. Treatment outputs can include current, power, energy delivered, percent drop in impedance, an impedance-based ratio, a percent impedance slope, and/or an airway wall impedance. Power and/or current of the system can be varied, within certain maximum thresholds, such as power, current, and/or impedance thresholds, to achieve the desired output parameter target during some or all of the treatment time. The systems and methods reduce the variability of the treatment efficacy otherwise due to variability in electrical properties of patient tissue and/or electrode contact.

Abstract: An arthroscopic cutting probe includes an outer sleeve having a longitudinal bore and an outer cutting window at its distal end. The outer sleeve has a metal body electrically insulated over its exterior except for a portion at least partially surrounding the outer cutting window which comprises an active electrode. An inner sleeve is rotationally disposed in a bore of the outer sleeve, and the inner sleeve has a distal end, a proximal end and a longitudinal passageway having an electrically conductive inner surface which comprises a return electrode. A dielectric cutting member is attached to the distal end of the inner sleeve and has a central passage extending from an inner cutting window at its distal end to an opening at its proximal end.

Abstract: Systems and methods for neuromodulation therapy are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a plurality of reference electrodes at the skin of a human patient and intravascularly positioning a plurality of ablation electrodes within a blood vessel lumen at a treatment site. The method can include obtaining impedance measurements between different combinations of the reference electrodes and the ablation electrodes and, based on the impedance measurements, identifying two or more electrode groups for treatment, where at least two of the electrode groups include a different one of the reference electrodes and a different one of the ablation electrodes.

Abstract: A surgical cryoablation system comprising a valve having a valve inlet and a valve outlet the valve inlet connectable to a source of cryogenic fluid at a pressure of greater than 4000 psi and the valve outlet connectable to a cryoablation probe, such that the valve outlet is in fluid communication with the cryoprobe such that the source of cryogenic fluid is in fluid communication with the valve inlet.

Abstract: Apparatuses and methods for treating a heart failure patient by ablating a nerve of the thoracic splanchnic sympathetic nervous system to increase venous capacitance and reduce pulmonary blood pressure. A method comprising: inserting a catheter into a vein adjacent the nerve, applying stimulation energy and observing hemodynamic effects, applying ablation energy and observing hemodynamic effects, applying simulation energy after the ablation and observing hemodynamic effects and monitoring for presence of the lung in the ablation zone. An alternative method comprising: inserting a catheter into a vein adjacent the nerve, detecting that lung tissue is a safe distance from an ablation zone, and delivering ablation energy to the target nerve when lung tissue is a safe distance from the ablation zone.

Abstract: A reinforcing clinical wrap is provided with integral thermal management. The clinical wrap includes a fluid circuit for a heat transfer medium to circulate between a fluid inlet and a fluid outlet. A shape conforming medium is disposed within a portion of the clinical wrap providing selective reinforcement support of the portion of the clinical wrap to conform to a surface of a patient. Non-limiting examples of the shape conforming medium may include a magnetorheological elastomer, a magnetorheological elastomer, a magnetorheological foam, a UV curable resin, and a phase change material.

Abstract: A pulmonary treatment catheter and handle system including a catheter assembly with insertion tube coupled to a handle assembly. The system is further removably coupleable to a delivery device, such as a flexible bronchoscope or endoscope, having a port for coupling the handle assembly thereto, and a working channel in communication with the port for delivering the catheter assembly through the delivery device and into a body lumen. Optionally, a port channel of the port can be collinear with the working channel of the delivery device. The catheter assembly, handle assembly, and delivery device cooperate together to facilitate delivery and positioning of a catheter electrode in a treatment site, such as an airway, conduit, or vessel for treatment of the tissue, while minimizing damage to portions of the catheter assembly, the delivery device, or both.

Abstract: An expandable balloon, which is coupled to a distal end of a shaft for insertion into an organ of a patient, includes an expandable membrane, one or more electrodes and one or more respective conductive coils. The one or more electrodes are disposed over an external surface of the membrane. The one or more respective conductive coils are each disposed proximate a respective RF ablation electrode. The one or more conductive coils are configured as magnetic sensors.

Abstract: Methods for estimating of the effectiveness of catheter ablation procedures to form lesions, and particular lesions which together form an ablation segment of an ablation line. Lesion effectiveness parameters are received, and effectiveness, optionally the joint effectiveness, of corresponding ablations (optionally planned, current, and/or already performed) is estimated. In some embodiments, estimating is based on use by computer circuitry of an estimator constructed based on observed associations between previously analyzed lesion effectiveness parameters, and observed lesion effectiveness. Additionally or alternatively, estimators may be constructed based on analytic functions. The estimator is used by application to the received lesion effectiveness parameters.

Abstract: Described embodiments include an apparatus that includes an intrabody probe and an electrode coupled to a distal end of the intrabody probe. The electrode includes a flexible electrically-insulating substrate, comprising a substrate surface. The electrode further includes a layer of an electrically-conducting metal covering at least part of the substrate surface. The electrode further includes a metallic sheet, comprising an inner sheet surface, and an outer sheet surface shaped to define multiple depressions. The electrode further includes an adhesive, which fills the depressions and bonds the outer sheet surface to the layer of the electrically-conducting metal. Other embodiments are also described.

Abstract: An assembly for performing an electrosurgical procedure. A cannula includes a cannula hub defining a middle bore having a smaller diameter than a proximal bore. An electrode includes an electrode head having an outer diameter smaller than the proximal bore and greater than the middle bore. A syringe includes a syringe head having a length sufficient to extend past the proximal bore, and an outer diameter sized to engage the middle bore to form an annular seal at an interface between the syringe and the cannula. A step may define a transition surface between the proximal bore and the middle bore, and at least one notch may be within the step to maintain fluid communication between the middle bore and the proximal bore when the electrode head is engaging the step. The cannula head may include first and second locking features configured to engage the syringe and electrode, respectively.

Abstract: An arthroscopic cutting probe includes an elongated shaft assembly having a distal end, a proximal end, and a longitudinal axis therebetween. A working end at the distal end of the elongated shaft assembly includes a first active electrode and a second active electrode The shaft assembly is rotates the first electrode relative to the second electrode about the longitudinal axis, and a return electrode is carried on the shaft assembly proximal of the working end. The first and second active electrodes are electrically coupled to each other and electrically isolated from the return electrode.

Abstract: An electrically conductive irrigation fluid for use in bipolar resectoscopic surgery, wherein the irrigation fluid being brought into contact with the electrode of a resectoscope and tissue being coagulated and/or resected by means of the electrode surrounded by the irrigation fluid, wherein the irrigation fluid includes metal ions. Moreover, the method relates to a resectoscopy system including a resectoscope and an irrigation system that is connected to the resectoscope, the resectoscope having a handle and a tubular shaft, and the shaft including an electrode instrument that is arranged so as to be longitudinally displaceable and has in its distal end region an electrode to which high-frequency current can be applied, wherein the irrigation system includes an irrigation fluid, which can be conducted through the shaft of the resectoscope to the electrode.

Abstract: A micro-sized cold atmospheric plasma accessory. The micro-sized cold atmospheric plasma accessory comprises a tube, an active electrode within said tube, and a nozzle at a distal end of said tube, said nozzle having an inner diameter less than 1 mm and a length less than 30 mm. A distal end inner diameter of said tube is greater than said inner diameter of said nozzle. The nozzle preferable is 15-25 mm in length. The nozzle may comprise stainless steel. The tube may have an inner diameter greater than 1 mm. The nozzle preferably has a distal end inner diameter less than 280 ?m. The micro-sized cold atmospheric plasma accessory may further comprise a return electrode on an outside of said tube.

Abstract: A medical device includes a body and at least one electrode disposed thereon. The electrode includes a metallic substrate, such as a platinum group metal, an alloy of platinum group metals, or gold. The surface of the substrate is modified in a manner that increases its effective surface area without inducing bulk heating. For example, the surface of the substrate can be laser textured and/or coated, such as with titanium nitride or iridium oxide.

Abstract: A medical device that has a first array of loop electrodes and a second array of loop electrodes. The first array of loop electrodes and the second array of loop electrodes are configured to expand within a uterus and deliver a therapy current to tissue defining the uterus.

Abstract: A method includes providing electrical energy to a transducer for sealing a vessel, where a frequency of the electrical energy is in an ultrasound range, controlling the electrical energy to achieve a predetermined velocity of an end effector coupled to the transducer, when the end effector is grasping the vessel, sensing parameters of the electrical energy when the end effector achieves the predetermined velocity, calculating power of the electrical energy based on the sensed parameters and estimating a size range of the vessel based on the power, and controlling the electrical energy to achieve a target velocity, which is determined based on the estimated size range of the vessel, to seal the vessel.

Abstract: A medical device includes a shaft including a central lumen configured to direct a flow of fluid through the shaft, and an electrode positioned at a distal portion of the shaft. The electrode includes an electrode lumen in fluid communication with the central lumen, and the electrode lumen is configured to receive the flow of fluid from the central lumen. The electrode also includes one or more channels angled relative to the electrode lumen, and the one or more channels are in fluid communication with the electrode lumen to receive the flow of fluid from the electrode lumen. The one or more channels are configured to divert the flow of fluid from the electrode lumen toward one or more outlets laterally offset from the electrode lumen.

Abstract: A method and system of adaptive cold atmospheric based treatment for diseased tissues, such as an area with cancerous cells, is disclosed. A plasma device generates a cold atmospheric plasma jet directed at the area having cancerous cells. A sensor is operable to sense the viability of the cancerous cells in the area. A controller is coupled to the plasma device and sensor. The controller is operative to control an initial plasma jet generated by the plasma device. The controller receives a sensor signal from the sensor to determine cell viability of the selected cells from the initial plasma jet. The controller adjusts the plasma jet based on the viability of the cancerous cells.