Abstract: A clip for engaging tissue includes a generally annular-shaped body defining a plane and disposed about a central axis extending normal to the plane. The body includes alternating inner and outer curved regions, defining a zigzag pattern about a periphery of the clip. The body is biased towards a planar configuration lying in the plane and deflectable towards a transverse configuration extending out of the plane. Tines extend from the inner curved regions, the tines being oriented towards the central axis in the planar configuration, and parallel to the central axis in the transverse configuration. The tines may include primary tines and secondary tines that are shorter than the primary tines. The primary tines may be disposed on opposing inner curved regions and oriented towards one another such that they overlap in the planar configuration.

Abstract: An introducer apparatus for deploying a self-expandable medical device, such as a stent, to a target area of a body vessel of a patient comprises a shaft having a proximal end and a distal end, and a distal end portion disposed at the shaft distal end. The distal end portion comprises an introducer body and at least one deployment member. The introducer body is sized and shaped relative to the self-expandable medical device such that the medical device is receivable on a surface of the introducer body when the medical device is in a compressed condition. The deployment member is configured and arranged relative to the introducer body for selectively restraining the self-expandable medical device in the compressed condition on the introducer apparatus surface.

Abstract: A removable filter having a collapsed state and an expanded state for capturing thrombi in a blood vessel is disclosed. The filter comprises a plurality of primary struts and a plurality of secondary struts. Each primary strut in the expanded state extends from a primary strut first end to an anchoring hook. Each primary strut extends arcuately along a longitudinal axis and linearly radially. The plurality of primary strut first ends are attached together along the longitudinal axis. Each secondary strut in the expanded state extends from a secondary strut first end to a free end. Each secondary strut extends arcuately along the longitudinal axis and linearly radially. The plurality of secondary struts are attached together along the longitudinal axis. The plurality of secondary struts centralize the filter in the expanded state in the blood vessel.

Abstract: Relatively pain free vaginal dilation is obtained by inserting into the vaginal canal a variable rigidity vaginal dilator having an inflatable balloon, in a manner that avoids insertion into the urethra. Air is introduced into the balloon. When the patient has gained confidence in the pain free use of the dilator, the balloon is deflated to remove the air and water is introduced into the balloon to expand it so that it contacts the vaginal canal and exerts a pressure thereon. This contact is maintained for a period of up to about 15 minutes. The pressure and/or contact time is stepwise sequentially increased to a maximum of about 12 atmospheres and a contact time of up to about 45 minutes, in accordance with a regimen and instructions established by the patient's healthcare provider and tailored to the patient's specific needs. A preferred embodiment of the dilator and a kit employing same, useful in the method of the invention, are disclosed.

Abstract: A suture system includes a plurality of double-stranded needles connected in sequence with a single-stranded needle at each end. The double-stranded suture needles incorporates two suture strands into a single needle. The suture system of the present invention facilitates the implantation of valve prostheses.

Abstract: A shunt rivet for implementation in the aorta and inferior vena cava to treat chronic obstructive pulmonary disease, and a method of treating chronic obstructive pulmonary disease.

Abstract: The invention relates to ophthalmology surgical procedures, and specifically to vitreous retinal surgical procedures for marking positions for incision/injection sites on the scleral surface of the eye. The types of ophthalmic vitreous surgical procedures for which are applicable include but not limited to, vitrectomies performed in hospital operating rooms and vitreous injections are routinely performed in doctor's offices for a variety of procedures to treat abnormal eye conditions. The invention discloses a range of scleral limbal marker for adult human patients, pediatric patients, and domestic and other animals. The invention discloses markers in materials capable of sterilization and for markers in materials suitable for disposal and packaged in vacuum sealed packages.

Abstract: A surgical device of suturing vascular vessels is described, as well as methods for suturing tissue employing the surgical device. The device includes at least one needle advanceable through tissue and into a needle capture element within a distal end of the surgical device to draw lengths of suture material which can then be used to close various puncture wounds, particularly in vascular tissue.

Abstract: Provided is an endoscopic suturing system for joining internal body tissues in a variety of procedures. The system comprises a suturing capsule releasably mountable to the distal end of an endoscope and capable of forming multiple stitches in tissue at a plurality of locations without requiring withdrawal of the capsule from the patient between stitches. Also enclosed is a suture lock to secure the placed stitch that is delivered by a device introduced through the working channel of the indwelling endoscope. Suitable control handles for the suturing capsule and for the suture lock delivery device positioned at the proximal end of the endoscope are provided to facilitate operation by the user.

Abstract: Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can comprise a three-step progressive treatment process that includes immediate restoration of blood flow, in-situ clot management, and/or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis and maceration. The progressive, or modular, treatment can be provided by a system or kit of one or more treatment devices.

Abstract: Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can comprise a three-step progressive treatment process that includes immediate restoration of blood flow, in-situ clot management, and/or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis and maceration. The progressive, or modular, treatment can be provided by a system or kit of one or more treatment devices.

Abstract: An apparatus for applying clips to tissue, comprises a plurality of clips, each of the clips including a proximal end having a pair of opposed jaws and a distal end including a linking feature, where the clips are linked to one another to form a clip chain with a linking feature of a distal-most one of the clips being gripped between the jaws of an immediately proximal one of the clips and a control linkage coupled to a proximal-most one of the clips for applying tension and compression to the clip chain in combination with a magazine containing the clip chain, the magazine including an abutment surface sized to prevent passage distally therebeyond of a clip having received between its jaws a linking feature of an immediately distal clip and an opening location within which the jaws of a clip are permitted to open to release a linking feature therefrom.

Abstract: A system and method for retrieving an implantable device includes a delivery catheter, a recapture section, and a sheath. The delivery catheter has a proximal end and a distal end. The recapture section is axially extendable from the distal end of the delivery catheter. The sheath has a proximal end and a distal end and a lumen sized to receive the delivery catheter. A portion of the lumen of the sheath is actuatable from an enlarged inside diameter to a reduced inside diameter to apply an inwardly directed force to the recapture section. The delivery catheter can be actuated with respect to the sheath to extend or retract the recapture section with respect to the delivery catheter.

Abstract: A method for occluding a blood vessel at a compression site is provided. Suction is applied to stabilize a surgical location adjacent the compression site. A first compressor is positioned proximal the surgical location and adjacent the blood vessel. The blood vessel is occluded with the first compressor in response to the positioning. Systems and apparatuses for using the method are also provided.

Abstract: The present invention involves a removable filter for capturing thrombi in a blood vessel. The filter comprises a plurality of struts having first ends attached together along a longitudinal axis of the filter. Each strut has a body member extending from the first end along the longitudinal axis to an anchoring hook defining a strut axis. Each strut is configured to move along a strut path relative to the longitudinal axis between an expanded state for engaging with the blood vessel and a collapsed state for filter delivery or retrieval. Each anchoring hook has an angle of up to about 90 degrees relative to the strut axis.

Abstract: A medical instrument includes a flexible sheath, a pivot base, a medical needle knife base, a medical needle knife, and a handpiece. The flexible sheath has a distal sheath portion insertable within a patient and has a proximal sheath portion. The pivot base is attached to the distal sheath portion. The needle knife base is pivotally connected to the pivot base and has a passageway. The medical needle knife is extendable from the passageway and is retractable within the passageway. The handpiece is connected to the proximal sheath portion and includes a manually-operated articulation control operatively connected to the needle knife base for pivoting the needle knife base with respect to the pivot base.

Abstract: An occlusion device includes a braiding of thin wires or threads tapering to the diameter of a catheter used for an intravascular implantation/explantation procedure and having a proximal retention area, a distal retention area at which ends of the wires or threads converge into a holder, and a cylindrical crosspiece interposed between the proximal retention area and the distal retention area, whereby the two retention areas are positioned on two sides of a shunt to be occluded in a septum following implantation while the crosspiece transverses the shunt. The holder exhibits a head section at its free end having an eyelet as a cross-hole which can be gripped and held in form-fit fashion by an implantation/explantation instrument. A surgical instrument having such a holder includes gripper tongs with gripping jaws which open and close by a push/pull system, and which force-fit grips the head section of the holder.

Abstract: An aspect of the invention relates to a forceps and collection assembly having multiple components and their related methods of use and manufacture. More specifically, an embodiment of the invention relates to a forceps for obtaining and collecting multiple samples in a collection assembly, such as a pouch. The forceps has multiple components including an insert cutting edge, a molded biopsy jaw, and an insert molded pouch.

Abstract: A thromboembolic removal system for treating ischemic stroke includes an elongate member and a receiver on a distal portion of the elongate member. The receiver includes structural members arranged to form a sleeve having a central lumen. A plurality of the structural members form engaging elements having apex regions that extend into the central lumen. During use of the thromboembolic removal system, the receiver is advanced over a body of thromboembolic material within a blood vessel, causing the body to be received into the central lumen, and causing the engaging elements to engage the body within the lumen.

Abstract: An apparatus for application of surgical clips to body tissue has a handle portion and a body extending distally from the handle portion and defining a longitudinal axis. The apparatus also has a plurality of surgical clips disposed within the body, and a jaw assembly mounted adjacent a distal end portion of the body. The jaw assembly includes first and second jaw portions movable between a spaced-apart and an approximated position. The apparatus also has a wedge plate longitudinally movable between the first and the second jaw portions, and a clip pusher configured to individually distally advance a surgical clip to the jaw assembly while the jaw portions are in the spaced apart position. The apparatus still further has an actuator at least partially disposed within the body and longitudinally movable in response to actuation of the handle portion and a jaw closure member positioned adjacent the first and second jaw portions to move the jaw portions to the approximated position.