Abstract: The present invention comprises a chest band adapted to encircle the torso of a patient after having implant surgery. The chest band couples to an arm cuff by means of an adjustable strap. The arm cuff fits loosely over the patient's arm above the elbow and is adjustable, comprising a single strap material with mating hook and loop fastener devices to allow adjustability for different sized arms. The chest band had a tapered end that over folds a second end and the tapered end includes a hook and loop faster that releasably couples directly to the fabric of the chest band. An adjustable wrist cuff includes a direct means for fastening the cuff to the chest band, or optionally, a second adjustable strap to enable selective coupling of the wrist cuff to the chest band.

Abstract: The present invention relates to a multi-column paddle structure and its uses thereof to provide neuromodulation therapy to a patient.

Abstract: Gastric apparatus is provided, including one or more sensors, adapted to generate respective sensor signals responsive to activity of a gastrointestinal tract of a subject. A control unit is configured with an eating detection threshold selected from the group consisting of: a predetermined threshold, and a threshold determined during a calibration procedure. The control unit is adapted to receive and analyze the sensor signals, and identify an aspect of at least one of the sensor signals indicative of periodic activity of the gastrointestinal tract. The control unit modifies the eating detection threshold responsive to identifying the aspect of the signals that is indicative of the periodic activity, and determines that an eating event has occurred responsive to the modified eating detection threshold and at least one of the analyzed sensor signals. Other embodiments are also described.

Abstract: An implantable device monitors and treats heart failure, pulmonary edema, and hemodynamic conditions and in some cases applies therapy. In one implementation, the implantable device applies a high-frequency multi-phasic pulse waveform over multiple-vectors through tissue. The waveform has a duration less than the charging time constant of electrode-electrolyte interfaces in vivo to reduce intrusiveness while increasing sensitivity and specificity for trending parameters. The waveform can be multiplexed over multiple vectors and the results cross-correlated or subjected to probabilistic analysis or thresholding schemata to stage heart failure or pulmonary edema. In one implementation, a fractionation morphology of a sensed impedance waveform is used to trend intracardiac pressure to stage heart failure and to regulate cardiac resynchronization therapy. The waveform also provides unintrusive electrode integrity checks and 3-D impedancegrams.

Abstract: The disclosed invention varies the width of the energy pulses with constant frequency and constant amplitude to regulate the amount of energy transferred from an energy transmitting device placed outside a patient to an energy receiver inside the patient. The pulse width is achieved with a modulation technique, PWMT, to control the amount of energy transferred from the external energy transmitting coil in the system to the implanted receiver. The PWMT is used to digitally vary the amount of power from the power amplifier that drives the transmitting coil. Compared to previous analog systems a PWM system is a great deal more efficient and can easily be controlled from a digital domain system such as a microprocessor.

Abstract: A method includes retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device. N is an integer greater than 1. The method further include categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles and performing comparisons between pairs of the N cardiac cycles. Each of the comparisons between two cardiac cycles includes detecting a mismatch between the two cardiac cycles when the two cardiac cycles are in different categories, and detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category. Additionally, the method includes classifying the rhythm of the N cardiac cycles based on a number of detected matches and detected mismatches.

Abstract: A blood pump system includes a first implantable housing, an implantable blood pump independent from the first implantable housing, and a percutaneous extension. The first implantable housing includes a rechargeable power storage device. The implantable blood pump supplements the pumping function of a heart. The rechargeable power storage device supplies electrical power to the implantable blood pump. The percutaneous extension is coupled to the rechargeable power storage device and adapted to traverse the skin. The percutaneous extension is configured to releasably connect to an external power supply adapted to provide power for recharging or supplementing the rechargeable power storage device to power the implantable blood pump.

Abstract: A method includes storing an electrogram (EGM) template in a memory. The EGM template includes first and second alignment points at first and second peaks of the EGM template, respectively. The method further includes identifying first and second peaks of a cardiac cycle EGM acquired by a medical device and selecting one of the first and second peaks of the cardiac cycle EGM to align with one of the first and second alignment points based on an order in which the first and second peaks of the cardiac cycle EGM occur. Additionally, the method includes aligning the selected one of the first and second peaks with one of the first and second alignment points and determining an amount of similarity between the cardiac cycle EGM and the EGM template after alignment.

Abstract: A system includes bio-medical units and an electromagnetic signal generating unit. A bio-medical unit includes a power harvesting module, a wireless communication module, a processing module, and a functional module that performs physical therapy function and generates physical therapy data. The electromagnetic signal generating unit that includes at least one signal generating module and a plurality of near field communication (NFC) modules. The signal generating module generates one or more signals and an NFC module converts the one or more signals into a component of electromagnetic signal, which the power harvesting module converts into a supply voltage that powers the other modules of the bio-medical unit.

Abstract: An article of clothing includes a clothing fabric and a plurality of bio-medical units integrated into the clothing fabric. A bio-medical includes a power harvesting module, a communication module, a processing module, a functional module, a die, and an IC package. The die supports the power harvesting module, the processing module, the communication module, and the functional module. The IC package houses the die and includes a mechanism for adhering to the clothing fabric.

Abstract: The disclosure describes techniques for associating therapy adjustments with posture states using a timer. The techniques may include detecting a patient adjustment to electrical stimulation therapy delivered to the patient, sensing a posture state of the patient, and associating the detected adjustment with the sensed posture state if the sensed posture state is sensed within a first period following the detection of the adjustment and if the sensed posture state does not change during a second period following the sensing of the sensed posture state.

Abstract: Electromagnetic signal delivery for tissue affected by neuronal dysfunction, degradation, damage, and/or necrosis, and associated systems and methods are disclosed. A method in accordance with one embodiment of the invention includes identifying an affected region, with the affected region including neuronal tissue that, at least during a pre-dysfunctional period, was in neural communication with neuronal tissue in a dysfunctional region. The affected tissue can be functionally adversely affected by neuronal dysfunction in the dysfunctional region. The method can further include applying electromagnetic signals to the neuronal tissue in the affected region. For example, the electromagnetic signals can be applied to a hypo-active neural region that is not physically damaged, and has been identified as likely to recover at least in part as a result of electromagnetic signals. Signals can be applied at sub-threshold levels to cortical and/or subcortical regions.

Abstract: The invention provides a method and system for analyzing an ECG signal to diagnose a heart condition of an individual. A sequence HBi of consecutive heart beat durations in an ECG signal is obtained. One or more first parameters are calculated in a calculation involving pairs of HBi and HBi-m, where m is a first predetermined integer and HBi-m is the duration of the heart beat that occurred m heart beats before the ith heart beat. One or more second parameters are calculated in a calculation involving pairs of HBi and HBBi-n, where n is second predetermined integer different from m. A diagnostic parameter is then calculated using the plurality of first parameters and the plurality of second parameters. The diagnostic parameter is compared to a predetermined threshold, and a diagnosis is made based on the comparison.

Abstract: An apparatus for monitoring fetal positions and fetal movements is provided. The apparatus includes a plurality of sensors, a signal pre-processor, a signal post-processor, and a fetal position judging processor. The sensors are attached on the abdomen of a maternal body to provide at least three measuring leads. The signal pre-processor receives a plurality of sensing signals from the sensors, and the signal pre-processor reduces noises in the sensing signals and amplifies the sensing signals to output a plurality of characteristic sensing signals. The signal post-processor receives the characteristic sensing signals from the signal pre-processor and separates out a plurality of fetal electrocardiograms (FECGs) corresponding to the leads. The fetal position judging processor analyzes the FECGs to obtain a characteristic waveform for each of the FECGs or directly calculates a fetal heart axis vector with respect to a front-side coordinate of the maternal body according to the FECGs.

Abstract: A first fluid status indicator of a pulmonary fluid status associated with pulmonary edema and a second fluid status indicator of a non-pulmonary fluid status can be used to provide an alert or to control a therapy for pulmonary edema. Additionally, intermittent cardiac blood volume redistribution therapy can be used to provide cardiac conditioning in heart failure patients.

Abstract: This document discusses, among other things, an apparatus comprising an implantable cardiac depolarization sensing circuit, an electrical stimulation circuit, and a pacing mode controller. The pacing mode controller is configured to deliver pacing therapy according to a first pacing mode that is a normal operating mode, and to deliver pacing therapy according to second and third pacing modes. The second and third pacing modes increase mechanical stress on at least a particular portion of the ventricle as compared to the pacing therapy delivered during the first pacing mode. The pacing mode controller alternates between the second and third pacing modes when pacing is changed from the normal operating mode to a stress augmentation mode. The pacing mode controller suspends the change from the normal operating mode to the stress augmentation mode when a condition to prevent the change is detected.

Abstract: An implantable medical lead having a modified electrode surface for imparting current density directionality within an electrode is disclosed. An implantable medical lead includes a lead body having a proximal section and a distal section having a pre-biased shape configured to secure the lead to an inner wall of a blood vessel. An electrode coupled to the distal section of the lead body includes a number of surface features on an inactive portion of the electrode that impart a current density directionality towards an active portion of the electrode that contacts the inner wall of the vessel. Methods for imparting current density directionality within an implantable lead electrode are also disclosed.

Abstract: A miniature microdrive system may be affixed to the skull and used to advance recording electrode bundles or injection cannula through the brain of freely moving test subjects, e.g., rodents. The microdrive may be constructed using a hybrid fabrication technique utilizing a printed circuit board and a small number of mechanical parts. The printed circuit board provides the base for both the electrical components and the mechanical components. The movement of a screw advances a shuttle that in turn moves an electrode bundle through the brain. Independently moving screws advance independent electrode bundles. The electrode wires are connected through the printed circuit board to a connector on the back of the board. Stainless steel cannulae are soldered to a grounding trace on the printed circuit board to guide the electrode bundle and provide a ground connection. With this system, multiple brain structures may be targeted simultaneously.

Abstract: Techniques for determining when to deliver a pre-excitation signal to damaged cardiac tissue, e.g., infarct tissue, of a ventricle during cardiac pacing are described. A medical device detects an intrinsic or paced atrial depolarization, and then detects a subsequent mechanical event, e.g., contraction, in a ventricle. As examples, the mechanical event may be detected by measuring ventricular movement, or changes in intracardiac or systemic blood pressure. The medical device determines an interval between the atrial depolarization and the ventricular mechanical event, which may be referred to as an A-Vm interval. By subtracting a pre-excitation interval (PEI) from the A-Vm, the medical device determines an A-V interval between an atrial depolarization and delivery of the pre-excitation signal.

Abstract: Systems and methods for temporarily pacing a patient's heart are provided. One system includes a hemostasis valve with an adjustable electrical connection, the adjustable electrical connection having one or more adjustable contacts. The adjustable contacts have a first, radially expanded configuration and a second, radially constricted configuration. In the radially constricted configuration, the adjustable contacts are configured to pierce through a layer of an elongate medical device that is disposed in the hemostasis valve. The elongate medical device has a distal electrode and a conductor extending along a portion of the elongate medical device. The adjustable contacts pierce through and make contact with the conductor, providing an electrical pathway to the distal electrode. Also provided are vascular access systems including hemostasis valve and a guide catheter, guide wire torquers with adjustable contacts and methods of temporarily pacing a patient's heart.