Abstract: The present disclosure provides a gastroretentive drug delivery device having an expandable structure. The drug delivery device includes: a capsule body; an arm moving part movable within the capsule body; an elastic body positioned between one end of the capsule body and the arm moving part and acting to move the arm moving part toward the other end of the capsule body; an arm support part movable within the capsule body; a capsule cap configured to engage the other end of the capsule body; a rail formed within the capsule body; and an arm configured to be unfolded by longitudinal movement of the arm moving part and move along the rail. A disintegrable immediate-release formulation is positioned between the arm moving part and the arm support part. A disintegrable sustained-release formulation is positioned between the arm support part and the capsule cap.

Abstract: An apparatus is provided for guiding the subcutaneous placement of a puncture indwelling drainage tube. The apparatus includes a cannula having a first puncture needle core with a first engagement portion that matches a second engagement portion of a second puncture needle core. The apparatus also includes a third puncture needle core having a third engagement portion that matches a fourth engagement portion of a fourth puncture needle core. Front ends of the four puncture needle cores all protrude from a front end of the cannula and four handles all protrude from the rear end.