Abstract: An integrated catheter placement system for accurately placing a catheter within a patient's vasculature is disclosed. In one embodiment, the integrated system comprises a system console, a tip location sensor for temporary placement on the patient's chest, and an ultrasound probe. The tip location sensor senses a magnetic field of a stylet disposed in a lumen of the catheter when the catheter is disposed in the vasculature. The ultrasound probe ultrasonically images a portion of the vasculature prior to intravascular introduction of the catheter. The ultrasound probe includes user input controls for controlling use of the ultrasound probe in an ultrasound mode and use of the tip location sensor in a tip location mode. In another embodiment, ECG signal-based catheter tip guidance is included in the integrated system to enable guidance of the catheter tip to a desired position with respect to a node of the patient's heart.

Abstract: An accurate real-time measurement of a displacement vector is achieved on the basis of the proper beamforming that require a short time for obtaining one echo data frame without suffering affections by a tissue motion. The displacement measurement method includes the steps of: (a) yielding ultrasound echo data frames by scanning an object laterally or elevationally using an ultrasound beam steered electrically and/or mechanically with a single steering angle over an arbitrary three-dimensional orthogonal coordinate system involving existence of three axes of a depth direction, a lateral direction, and an elevational direction; and (b) calculating a displacement vector distribution by implementing a block matching on the predetermined ultrasound echo data frames yielded at more than two phases.

Abstract: Provided are an ultrasonic diagnostic apparatus and a method of operating the same. The ultrasonic diagnostic apparatus includes: a first ultrasonic transceiver that transmits an ultrasonic signal and receives a first echo signal that is reflected, through a deactivated probe from among a plurality of probes; a gel detector that determines whether gel is applied on the deactivated probe based on the received first echo signal; and a controller that activates the deactivated probe when it is determined that the gel is applied on the deactivated probe.

Abstract: Methods and devices for both imaging and treating uterine fibroid tumors in one real-time system are provided. One minimally invasive method comprises introducing a sheath into a uterus and determining a location of a fibroid using a visualization element within or on the sheath. Upon identification, a portion of the sheath is steered to position at least one treatment needle at the determined location. The needle is then anchored in uterine tissue and the fibroid treated with the needle.

Abstract: The present disclosure involves a method and apparatus for attaching two electrical dies by wire bonding and then encasing the assembly in a protective casting that works by arranging two dies into a fixture conducive to wire bonding. Doped epoxy may be immediately dispensed over the assembly to form a near-net-shape protective cover, or Drive Can.

Abstract: An ultrasonic transducer includes “m” first ultrasonic elements including first diaphragms, and “n” second ultrasonic elements including second diaphragms. “m” represents a number of the first ultrasonic elements and is an integer of 1 or more. Each of the first diaphragms has a first area. “n” second ultrasonic elements includes second diaphragms. Each of the “n” second diaphragms has a second area being smaller than the first area. “n” represents a number of the second ultrasonic elements and is an integer larger than “m”. The “m” first ultrasonic elements are electrically connected in series in a case where “m” is an integer of 2 or more. The “n” second ultrasonic elements are electrically connected in series. B/A is within a range of 0.9 to 1.1, when a total sum of the first areas is “A” and a total sum of the second areas is “B”.

Abstract: Certain aspects relate to apparatuses and techniques for non-invasive optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications, including assessing the presence and severity of tissue conditions, such as burns and other wounds.

Abstract: Disclosed is an ultrasonic oscillator that heats a target using ultrasonic waves. The ultrasonic oscillator includes: a plurality of ultrasonic oscillation elements that oscillates the ultrasonic waves; a retention portion that retains the plurality of ultrasonic oscillation elements in a state where the ultrasonic oscillation elements are arranged along a concave thereof opposing the heating target; and a controller that controls the ultrasonic oscillation elements so as to oscillate the ultrasonic waves.

Abstract: The present invention generally relates to paramagnetic contrast agents and a Dynamic Contrast Enhanced-MRI method for the non-invasive estimation of the delivery of a macromolecular anticancer drug or pro-drug within pathological tissues and, especially, in solid tumors and for the optimization of anticancer therapies.

Abstract: An image processing method enables an elasticity image of a body including a cavity to be produced on the basis of the material(s) forming the body, wherein the method includes the steps of: receiving a deformation image illustrating a field of movement of the points of the body on the basis of a pressure difference in the body, estimating a shape function of the body from the deformation image, calculating an elasticity image of the body on the basis of the shape function, of the pressure difference and of the deformation image.

Abstract: An ultrasound system and method that can include: a receive beamformer configured to receive signals from a transducer; a processor coupled to the receive beamformer, the processor configured to: analyze echo data reflected from a region of interest, the echo data elicited by a transmitted pulse sequence; using the echo data, determine a central tendency of a signal magnitude from regions of adherent microbubbles over time within the region of interest; determine a time series of the signal magnitude; using the time series, determine an initial signal magnitude parameter; obtain a saturated signal parameter and a residual signal parameter using the time series; and determine a relative indication of information indicative of the residual signal magnitude versus the saturated signal magnitude.

Abstract: A subject-information acquisition apparatus includes a light source; a holding member configured to hold a subject so as to surround the subject; at least one transducer configured to receive an acoustic wave generated by irradiating the subject with light from the light source; and a signal processing unit configured to obtain distribution information using a received signal output from the transducer. The holding member includes a marker that absorbs the light and generates an acoustic wave.

Abstract: In an example, an optical system can include a polarization scrambler coupleable to a tunable first optical source configured to generate a coherent optical output. The system can include an intra-body optical sensor such as a an intravascularly-deliverable optical fiber transducer, configured to be coupled to the tunable first optical source through the polarization scrambler, the polarization scrambler configured to vary a polarization state of the optical energy provided by the tunable first optical source, the intravascularly-deliverable optical fiber transducer configured to reflect a portion of the optical energy modulated in response to a vibration, pressure, or strain.

Abstract: Measurement or imaging of elastic wave nonlinear scatterers with a memory of scattering parameters comprises selecting LF pulses having characteristics to change the scattering parameters of nonlinear scatterers. A transmit time relation is selected so that the incident HF pulse propagates sufficiently close to the LF pulse that the effect of the incident LF pulse on its scatterer parameters is observed by the HF pulse. At least two elastic wave pulse complexes comprising a high frequency (HF) pulse and a selected low frequency (LF) pulse are transmitted towards the region. Received HF signals are combined to form nonlinear HF signals representing the scatterers with memory, with suppression of received HF signals from other scatterers. At least one of the received HF signals may be corrected by time delay correction and/or speckle correction with a speckle correction filter, determined by movement of the scattering object. Systems are also disclosed.

Abstract: Systems and methods are disclosed for locating the parathyroid. In one aspect, temporal variation among a plurality of images is evaluated and at least one image is enhanced according to the temporal variation. The image may be enhanced to one or both of reduce conspicuity of the thyroid gland and enhance conspicuity of the parathyroid gland. Some of the plurality of images may be adjusted in order to align representations of a target portions. Adjustments may be based locations of one or more organs or one or more artificial markers affixed to a living body in the plurality of images. A local positioning system (LPS), GPS, or other locating system may be used to position a living body, align the plurality of images, or to guide the positioning of objects relative to the living body. An elastomeric gel marker for imaging applications is also disclosed.

Abstract: Systems and methods are provided for detecting the flow of blood or other fluids in biological tissue by illuminating the biological tissue with two or more beams of coherent light and detecting responsively emitted light. A difference in wavelength, coherence length, beam divergence, or some other property of the beams of illumination causes the beams to preferentially scatter from, be absorbed by, or otherwise interact with respective elements of the biological tissue. Flow properties in one or more regions of the biological tissue (e.g., a region with which both beams of light preferentially interact, a region with which only one of the beams preferentially interacts) could be determined based on detected responsively emitted light from the biological tissue. Variations in speckle patterns over time and/or space, Doppler shifts, or some other properties of the detected light could be used to determine the flow properties.

Abstract: An optical coherence tomography (“OCT”) system that includes a planarizing transparent material is provided. The OCT system includes an OCT probe comprising: a body having a distal end and a proximal end; a positioner adapter located at the proximal end; a connector to an OCT analysis device, the connector located at the proximal end; and, an OCT scan lens located at the distal end. The OCT system further includes: a transparent material configured to planarize tissue at a scan plane of the OCT scan lens.

Abstract: An X-ray CT system (1000) includes a CT scanner (300) which obtains diagnostic images of a patient, a chemical liquid injector (100) which injects a chemical liquid into a patient whose images are obtained, an operation device (400), I/Fs (320, 421) for transmitting and receiving data between the CT scanner (300) and the operation device (400) and I/Fs (120, 420) for transmitting and receiving data between the chemical liquid injector (100) and the operation device (400). The operation device includes an input section used to set an injection condition for the chemical liquid by the chemical liquid injector (100) and an imaging condition by the CT scanner (300), a control section for controlling operation of the chemical liquid injector (100) and operation of the CT scanner (300) in accordance with the setting and a display section (450) for displaying information relating to the setting of the injection condition and the imaging condition and an obtained image.

Abstract: The present invention relates to a method of diagnosing, or providing a prognosis to, or for providing the likelihood of developing, malignant melanoma in a subject, the method comprising the steps of: (a) measuring two or more markers in blood perfusion dynamics at and/or around a skin lesion site; and (b) determining if the two or more markers is different to a normal value. The invention also relates to a device for diagnosing/providing a prognosis to/for malignant melanoma in a subject.

Abstract: Disclosed is a pullback system, which has a simplified and miniaturized structure and an advanced function. The pullback system includes a central unit, which includes a rotation transducer part that rotates, and a stretchable part that is connected to a side of the rotation transducer part to rotate together with the rotation transducer part and that has a stretchable property, and a first unit rotatably coupled to a portion of the central unit. As the first unit moves in a first direction oriented from the rotation transducer part to the stretchable part or in a second direction opposite to the first direction, the stretchable part contacts or stretches.