Abstract: A housing assembly is provided to define a locally controlled environment to maintain a localized clean work area without the need to maintain cleanliness levels in an entire room as in conventional clean rooms. The housing assembly includes a HEPA filter coupled to an air inlet to filter all of the air entering the housing. An air blower is coupled to the air inlet to feed filtered air into the housing assembly and to maintain a positive air pressure in the housing assembly to prevent unfiltered outside air from entering. Prefillable medical containers, such as syringe barrels and syringe tip closures, are introduced into the housing assembly where the syringe barrels and tip closures are cleaned with filtered ionized air and the tip closures are coupled to the barrels. A thin coating of a lubricant is applied to the inner surface of each of the syringe barrels. The syringe barrels can be filled with a substance.

Abstract: A carton-shaping machine includes a material conveying mechanism, an opening mechanism, a shaping mechanism, and a band sticking mechanism combined on a worktable. A vertical and a horizontal cylinder of the opening mechanism control fixing members to force needles on them insert firmly in an upper folding portion of a carton and turn the carton to extend to standing position so as to permit opening process operated with accuracy. Then, the band sticking mechanism may seal the bottom portion of the carton and the carton is moved to the packing process, without any need of manual work to turn it for a right angle to stand upright.