Patents Examined by Louise D. Leary
  • Method and diagnostic agent for enzyme substrate stabilization using 1-arylsemicarbazides
    Patent number: 5391482
    Abstract: The present invention is concerned with the use of 1-arylsemicarbazides of the general formula:Ar--NH--NH--CON.sub.2wherein Ar is an aryl radical optionally substituted by alkyl, alkoxy or halogen, for the stabilization of an enzyme substrate from which, by enzymatic hydrolysis, a leuko coloured material can be formed which, in turn, can be reacted by an oxidation agent to give a colored material. The present invention also provides a corresponding stabilizing process and a diagnostic agent containing such a stabilizer.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: February 21, 1995
    Assignee: Boehringer Mannheim GmbH
    Inventor: Dieter Mangold