Patents Examined by Luther Behringer
  • Patent number: 10413278
    Abstract: Various methods of performing ultrasound contrast assisted therapy are provided. One such method includes delivering a plurality of microbubble-based ultrasound contrast agents to a target area and disrupting the microbubble-based ultrasound contrast agents by delivering tone bursts of ultrasound to the target area. The oscillation of the microbubble-based ultrasound contrast agents can be achieved by delivering ultrasound tone bursts of greater than 5 acoustic cycles with a pulse repetition frequency of between 0.01 and 20 Hz, with pressure greater than 0.3 MPa.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: September 17, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Xucai Chen, Jianjun Wang, John J. Pacella, Flordeliza S. Villanueva
  • Patent number: 10413258
    Abstract: An apparatus for generating a medical device implantation warning includes a processor to automatically generate a spatial implantation envelope of a first medical device. The envelope defines a spatial extent of a region of implantation around a first medical device prior to, during, and/or after deployment of the first medical device for implantation. If a second medical device, such as a pigtail catheter, strays into the area, an alarm is generated to warn a medical professional to withdraw the pigtail catheter, before deployment continues.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: September 17, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Guillaume Julien Joseph Pizaine, Olivier Pierre Nempont, Vincent Maurice André Auvray, Raoul Florent
  • Patent number: 10390992
    Abstract: A thermal control unit for delivering temperature-controlled fluid to one or more patient therapy devices (e.g. pads, blankets, etc.) that are in contact with a patient is disclosed. The thermal control unit allows multiple patient therapy devices to be fluidly coupled thereto and to individually monitor the temperatures, flow rates, and/or connections/disconnections of the patient therapy devices. A user interface enables a user to designate outlet ports to the therapy devices as active or inactive, and the control unit provides notifications to the user if any of the active ports experience an undesired condition, or if a patient therapy device is connected to an inactive port. The user interface further allows the user to designate one of multiple patient temperature probes as a primary probe. The primary probe is used to control the temperature of the fluid circulating through the control unit.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: August 27, 2019
    Assignee: Stryker Corporation
    Inventors: Christopher John Hopper, Brian Schultz, Roy E Holmberg, III, Jonathan David Campbell, Marco Constant
  • Patent number: 10383603
    Abstract: An ultrasound diagnostic device generating a frame reception signal by compounding sub-frame reception signals through spatial compounding, the ultrasound diagnostic device including a control circuit that includes a sub-frame enhancement map creator creating a plurality of sub-frame enhancement maps, each corresponding to one sub-frame reception signal, the creating of each of the sub-frame enhancement maps being performed by calculating, for a pixel region reception signal in a corresponding sub-frame reception signal, an enhancement amount in accordance with a characteristic value calculated based on the pixel region reception signal, the pixel region reception signal corresponding to a pixel region composed of one or more pixels, and an enhancement-applied reception signal generator generating an enhancement-applied frame reception signal by compounding pixel region reception signals included in the sub-frame reception signals based on pixel region positions, taking into account the enhancement amount in
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: August 20, 2019
    Assignee: KONICA MINOLTA, INC.
    Inventors: Kazuya Takagi, Yoshihiro Takeda, Akihiro Kawabata
  • Patent number: 10368970
    Abstract: An apparatus includes at least one transducer configured to (i) generate first ultrasonic signals and receive reflected first ultrasonic signals and (ii) generate second ultrasonic signals. The apparatus also includes a diagnostic ultrasound system configured to control generation of the first ultrasonic signals and to perform image processing using the reflected first ultrasonic signals in order to generate real-time images of tissue in an animal. The apparatus further includes a therapeutic ultrasound system configured to control generation of the second ultrasonic signals in order to ablate targeted tissue in the animal and sterilize the animal. The at least one transducer could include (i) a diagnostic transducer configured to generate the first ultrasonic signals and receive the reflected first ultrasonic signals and (ii) a therapeutic transducer configured to generate the second ultrasonic signals. A portable handheld housing could contain the at least one transducer.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: August 6, 2019
    Inventor: Randy L. King
  • Patent number: 10368850
    Abstract: Systems and methods are provided for utilizing an MRI image and real-time an ultrasound images to guide and/or restrict the movement of an ultrasound probe in position for collecting a biopsy core. A real-time ultrasound image is acquired and fused with pre-operative imaging modalities, such as an MRI image, to provide a three-dimensional model of the prostate. A multi-link robotic arm is provided with an end-effector and an ultrasound probe mounted thereto. Sensor information is used to track the ultrasound probe position with respect to the 3D model. The robotic arm allows for the implementation of a virtual remote center of motion (VRCM) about the transrectal probe tip, an adjustable compliant mode for the physician triggered movement of probe, a restrictive trajectory of joints of the robotic arm and active locking for stationary imaging of the prostate.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: August 6, 2019
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Ali Kamen, John Benson, Richard Chiao, Dorin Comaniciu, Ankur Kapoor, Yuehaw Khoo, Andrzej Milkowski
  • Patent number: 10362983
    Abstract: A rectal near infrared (NIR) scanning polarization imaging system uses NIR Photonic Prostatoscopy Analyzer (NIRPPA) for prostate cancer detection using light. The NIRPPA consists of a portable rectal NIR scanning polarization imaging unit and an optical fiber-based rectal probe capable of recording sets of 2D images of a prostate through rectum at different wavelengths and depths and obtaining a three dimensional (3D) image of the prostate and 3D locations of abnormal tissue inside the prostate. Diode lasers/light emission diodes (LEDs) with selected emitting wavelengths are used in the NIR spectral range from 650 nm to 2,400 nm corresponding to the four tissue optical windows (#I, 650 nm-950 nm; #II, 1,100 nm-1,350 nm; #III, 1,600 nm-1,870 nm; and #IV, 2,100 nm-2,300 nm). The fingerprint absorptions of water (H2O), Oxyhemoglobin (HbO2) and deoxyhemoglobin (Hb) in the prostate are used as native biomarkers for prostate cancer detection.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: July 30, 2019
    Inventors: Robert R. Alfano, Wubao Wang, Yang Pu, Yury Budansky, Laura Sordillo, Guichen Tang, James Eastham
  • Patent number: 10357227
    Abstract: A medical apparatus (200, 300, 400, 500) determines the concentration distribution of sonically dispersive elements (606, 2001) within a subject (306, 604, 1004), wherein the medical apparatus comprises: a memory (212) for storing machine executable instructions (224, 226, 228, 230, 232, 318) and a processor (206) for executing the machine executable instructions. Execution of the instructions cause the processor to: receive (100) shear wave data (214) descriptive of the propagation of shear waves (310, 608, 1118) within the subject for at least two frequencies; determine (102) a mechanical property (316, 618, 620) of the subject using the shear wave data at each of the at least two frequencies; determine (104) a power law relationship (218, 702) between the at least two frequencies and the mechanical property; and determine (106) the concentration distribution of the sonically dispersive elements within the subject using the power law relationship and calibration data (222, 704, 800).
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: July 23, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Ralph Roman Sinkus, Simon Auguste Lambert, Leon Christiaan Ter Beek
  • Patent number: 10342510
    Abstract: The invention relates to an interventional device (10) including a plurality of signal assemblies, a method of assembling such interventional device (10), an assembling system for such interventional device (10) and a corresponding software product. In order to provide a number of signal assemblies including, for example, ultrasound transducers (40) in an interventional device (10) with a reduced risk of thrombi formation or similar complications a desired flush and smooth surface of a casing (15) of the interventional device (10) is achieved if the signal assemblies are inserted in such a manner that they are urged into their respective positions from inside the casing (15) after such insertion.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: July 9, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Szabolcs Deladi, Cornelius Antonius Nicolaas Maria Van Der Vleuten, Antonius Johannes Josephus Rademakers, Johannes Gerardus Van Beek
  • Patent number: 10335231
    Abstract: A method of forming a microwave applicator comprising forming a body comprising dielectric material so that there is a void in the dielectric material, and depositing conductive material in the void to form a feed for coupling energy into the dielectric material.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: July 2, 2019
    Assignee: EMBLATION LIMITED
    Inventors: Gary Beale, Eamon McErlean
  • Patent number: 10328238
    Abstract: In a catheter system and method for controlling such a system, an elongate hollow shaft has a proximal end connected to a handle and a distal end remote from the handle. A working component is carried by the shaft and has at least one characteristic that is adjustable. An actuator is rotatably mounted on the handle for selectively adjusting at least one characteristic of the working component. A control line extends at least in part within the shaft. The control line operatively couples the actuator with the working component such that rotation of the actuator relative to the handle effects linear translation of the control line to adjust the at least one characteristic of the working component.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: June 25, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Russell D. Terwey, James Paul Goodman, Kevin Gin Park
  • Patent number: 10321895
    Abstract: In an ultrasound diagnostic apparatus of the present invention, the controller writes and reads element data of one frame into and out from two or more buffer memories 21a, 21b, . . . 21i sequentially frame by frame and assigns the element data of one frame sequentially read out from the buffer memories to a plurality of arithmetic blocks of a signal processor, wherein the element data assigned is subjected to processing by each of a plurality of arithmetic cores in the plurality of arithmetic blocks to produce an image signal.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: June 18, 2019
    Assignee: FUJIFILM Corporation
    Inventor: Yoshiaki Satoh
  • Patent number: 10314509
    Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: June 11, 2019
    Assignee: TOSENSE, INC.
    Inventors: Matthew Banet, Susan Meeks Pede, Marshal Singh Dhillon, Kenneth Robert Hunt
  • Patent number: 10292680
    Abstract: An ultrasonic probe includes a capacitive micromachined ultrasonic transducer (cMUT) array configured to generate ultrasonic waves, an integrated circuit to which the cMUT array is bonded, and a flexible printed circuit board having one end connected to the integrated circuit to output signals to the integrated circuit, the integrated circuit including pads provided on the integrated circuit and an anisotropic conductive film (ACF) provided on the pads, and the one end of the flexible printed circuit board being connected to the ACF to thereby connect the flexible printed circuit board to the integrated circuit.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: May 21, 2019
    Assignees: SAMSUNG ELECTRONICS CO., LTD., KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Youngil Kim, Jong Keun Song, Baehyung Kim, Yongrae Roh, Eunsung Lee, Kyungil Cho, Minseog Choi
  • Patent number: 10274452
    Abstract: The present invention relates to a method for fabricating a semiconductor device for stimulation and/or data recording of biological material to a such semiconductor device. The method comprises providing a semiconductor substrate comprising a first insulating layer; providing a patterned conductive layer on top of the first insulating layer; depositing and patterning a second insulating layer atop the patterned conductive layer; growing carbon nano-sheets atop the second insulating layer; and defining carbon nano-sheet electrode areas on the second insulating layer by etching away the carbon nano-sheets outside of the carbon nano-sheet electrode areas.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: April 30, 2019
    Assignees: IMEC, KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
    Inventors: Nadine Collaert, Daire J. Cott, Michael De Volder
  • Patent number: 10265514
    Abstract: A sensing and stimulation system includes a central hub, and a plurality of flexible arms extending from the central hub. Each of the arms includes at least one electrode and at least one sensor. Each of the arms is configured to perform sensing and stimulation including electrically stimulating biological material, and sensing biological responses and changes. The system includes a port configured to be alternatively connected to a remote control module for wireless operation of the system and a leaded connector for wired operation of the system.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: April 23, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: William Harding, Scott Mark
  • Patent number: 9687384
    Abstract: The present invention relates to a sliding-type apparatus for thermo-therapeutic treatment comprising: a body (1100) on which a thermo-therapeutic treatment device (1010) is arranged; a cover (1250) which is slid, and covers said thermo-therapeutic treatment device (1010); and guide grooves which are formed to slide on said body (1100). According to the present invention, if the apparatus for thermo-therapeutic treatment is not used, a lower bed member is slid such that the lower bed member can be overlapped with the body whereby a space can be easily utilized, and if the apparatus for thermo-therapeutic treatment is used, the lower bed member is easily unfolded in a sliding manner.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: June 27, 2017
    Assignee: CERAGEM CO., LTD.
    Inventor: Ji Hoon Park
  • Patent number: 9681913
    Abstract: An elongated shaft assembly includes a rotatable inner cutting sleeve and a non-rotating outer sleeve. A window of the inner cutting sleeve is selectively rotatable within an opening of the non-rotating outer sleeve to cut tissue with a sharpened cutting blade when rotated in a first rotational direction and to cut tissue with an electrode when rotated in a second rotational direction.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: June 20, 2017
    Assignee: RELIGN Corporation
    Inventors: Benedek Orczy-Timko, Aaron Germain
  • Patent number: 9618590
    Abstract: An MRI-compatible tip assembly for an MRI-compatible medical device includes a first tubular member, a second tubular member, a ring electrode, and a tip electrode. The tip electrode proximal end is secured to the first tubular member distal end. The second tubular member distal end is inserted through the ring electrode and is secured to the first tubular member proximal end. When assembled, the tip assembly is a substantially rigid structure. Each tubular member has a recessed portion for a tracking coil.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 11, 2017
    Assignee: MRI Interventions, Inc.
    Inventor: Jesse Flores
  • Patent number: 9597140
    Abstract: A device, system and method for temperature-based lesion formation assessment and mapping functionality using an accessory usable with an over-the-wire balloon catheter. The device may include a first annular element, a plurality of wires coupled to the first annular element, and a second annular element, the plurality of wires passing from the first annular element through the second annular element and into an elongate wire conduit coupled to the second annular element. At least one of the plurality of wires may include at least one temperature sensor and/or at least one mapping electrode. The first annular element coupled to an outer surface of a sheath. As a balloon catheter is advanced out of the sheath lumen, the distal tip of the catheter engages the second annular element and pushes the wires out of the sheath lumen, everting them over the balloon of the catheter.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: March 21, 2017
    Assignee: Medtronic CryoCath LP
    Inventor: Teresa Mihalik