Patents Examined by Lynnette F.. Smith
  • Tandem synthetic HIV-1 Peptides
    Patent number: 5876731
    Abstract: Novel synthetic peptides are provided which are candidate vaccines against HIV-1 and which are useful in diagnostic application. The peptides comprise an amino acid sequence of a T-cell epitope of the gag protein of HIV-1, specifically p24E linked directly to an amino acid sequence of a B-cell epitope of the V3 loop protein of an HIV-1 isolate and containing the sequence GPGR, and/or the gp41 containing the sequence ELKDWA. Multimeric forms of the tandem synthetic peptides are provided.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 2, 1999
    Assignee: Connaught Laboratories Limited
    Inventors: Charles D. Y. Sia, Pele Chong, Michel H. Klein