Abstract: A phototherapy device includes: a treatment light emitter configured to emit treatment light for causing a reaction of a drug; a narrow band light emitter configured to emit narrow band light having part of wavelength band of a visible light range; an imager configured to obtain a narrow band light image which is formed using the narrow band light applied onto an application position of the treatment light; a narrow-band-light image variation calculator configured to calculate a time variation between the narrow band light image obtained before an application of the treatment light and the narrow band light image obtained after the application of the treatment light; and a display image generator configured to generate a display image including information based on the calculated variation.

Abstract: Systems and methods are disclosed for flexibly controlling laser pulses being output from a laser system. An example surgical system comprises a laser, an optical switching device, and a laser pulse controller. Optical switching control signals communicated by the laser pulse controller control the length of a pulse picking cycle and the number of laser pulses in each pulse picking cycle to be output from the laser system. The number of laser pulses in each pulse picking cycle to be output from the laser system may be adjustable in a range that includes more than 50% of the laser pulses in each pulse picking cycle.

Abstract: A device for laser lipolysis is described, comprising a treatment laser source adapted to emit radiation within a wavelength range strongly absorbed by the human body adipocytes. The device further comprises a hand-piece having a handle and a cannula that is adapted to be inserted into an adipose tissue of a patient undergoing a lipolysis treatment. An optical fiber is adapted to connect the laser source to the hand-piece, and the cannula is adapted to receive a distal portion of the optical fiber. The device further comprises a detection system, for detecting the movement speed of the hand-piece when in use, and a control unit, functionally connected to the treatment laser source and adapted to control at least one emission parameter of the treatment laser source, so as to modulate the power emitted by the treatment laser source based on the movement speed of the hand-piece detected by the detection system.

Abstract: According to an example, a handle assembly for a medical device may comprise a handle body, and a first knob for controlling movement of a distal portion of the medical device, the first knob may comprise a first rotational axis, and a second knob for controlling movement of the distal portion of the medical device, the second knob may comprise a second rotational axis, wherein the first rotational axis may be spaced from the second rotational axis.

Abstract: Systems and methods are provided for modulating laser treatment on the eye. In use, an eye of a patient is scanned using a laser scanning system to produce a scan result. A mapping of the eye is created based on the scan result. Additionally, a modulated treatment of the eye is created based on the mapping. Further, a laser illumination light beam is delivered to a first location on the eye of the patient in accordance with the modulated treatment.

Abstract: Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided.

Abstract: Provided is a laser ablation catheter, including a laser optical fiber bundle, an adjustable head, an outer tube, an overtube and a connector. The outer tube wraps the laser fiber bundle. The adjustable head includes an adjustable stent, the adjustable stent is made of a shape memory material and is sleeved outside one end of the outer tube. The connector is connected to the other end of the outer tube, and the laser fiber bundle can be connected to a laser generator through the connector. The overtube is sleeved outside the adjustable stent for compressing the adjustable stent. At least one end of the adjustable stent is a movable end, and the movable end is slidingly connected to the outer tube. When the overtube is withdrawn, the movable end can provide conditions for the deformation of the adjustable stent.

Abstract: A lighting arrangement for general lighting, comprising a first light source 10 adapted to emit a first light substantially only in a first predetermined spectrum in a range from 615 nm to 690 nm, one or more driver circuits adapted to provide a first pulsed driving current to the first light source for producing the first light pulsing with a first peak radiant power in the first predetermined spectrum sufficient to induce a photo-biomodulation response in a human body, and a second light source adapted to emit a second light, the second light source being capable of emitting at least 250 lumens.

Abstract: A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) or a heart valve includes a light source (124), a first light guide (122A), a second light guide (122A), and a guide bundle (152). The light source (124) generates light energy. The first light guide (122A) receives the light energy from the light source (124) and has a guide proximal end (122P). The second light guide (122A) receives the light energy from the light source (124) and has a guide proximal end (122P). A guide bundle (152) is in optical communication with the light source (124). The guide bundle (152) bundles the first light guide (122A) and the second light guide (122A). The guide bundle (152) includes a first ferrule (778) that engages the guide proximal end (122P) of the first light guide (122A) and a second ferrule (778) that engages the guide proximal end (122P) of the second light guide (122A).

Abstract: Methods and systems for recommending at least one patient interface device from among a plurality of patient interface devices for a patient. The methods and systems monitor an initial stress response of the patient upon being exposed to each of the potential patient interface devices of the plurality and from such monitoring select a device or devices that produce lesser stress responses.

Abstract: Dermatological systems and methods for providing a therapeutic laser treatment using a handpiece providing contact cooling of the skin and contact sensing to ensure proper contact between therapeutic laser and the contact cooling element and skin of the patient.

Abstract: Systems and methods are disclosed for generating an electro-anatomical map of the heart. Techniques disclosed include measuring groups of activation signals. The activation signals of each group are measured by respective electrodes of a mapping catheter that is placed at a respective position in the heart. Where at least one electrode of the mapping catheter that measured an activation signal of one group spatially overlapped with a respective electrode of the mapping catheter that measured an activation signal of another group. Techniques disclosed further include obtaining, based on the groups of activation signals, respective sets of time measurements, utilizing the overlapping electrodes. And, constructing the electro-anatomical map based on the obtained sets of time measurements.

Abstract: Modulation of foreign body responses in living tissue, and more particularly, devices and related methods for light-based modulation of foreign body responses in living tissue are disclosed. Light sources are disclosed that provide light with characteristics for modulation of foreign body responses that may be elicited by percutaneous and/or subcutaneous devices, including medical devices and other consumer electronic devices. Light delivery structures are disclosed that propagate light from the light sources to irradiate associated subcutaneous tissues. Modulation of foreign body responses may include inhibiting collagen and fibrous tissue generation, modulating inflammation and healing, and/or increasing nitric oxide production and/or release. By modulating foreign body responses associated with percutaneous and/or subcutaneous devices, performance characteristics and lifetimes of such devices may be improved.

Abstract: A catheter system for treating a treatment site within or adjacent to a vessel wall includes a light source, a balloon, a light guide, and an optical analyzer assembly. The light source generates light energy. The balloon is positionable substantially adjacent to the vascular lesion. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The light guide receives light energy from the light source at a guide proximal end and guides the light energy toward a guide distal end and into the balloon interior. The optical analyzer assembly is configured to optically analyze light energy emitted from the guide proximal end of the light guide.

Abstract: The present disclosure relates generally to devices, assemblies, and methods for removing a bodily mass from a body cavity. In some embodiments, a medical device may include a scope including a working channel and a sheath having a wall defining a lumen, wherein the sheath extends beyond a distal end of the scope. The medical device may further include a laser extending through the working channel, adjacent the sheath.

Abstract: The present disclosure provides a master manipulator device for a robot. The master manipulator device comprises an end control assembly and a posture adjustment member. The posture adjustment member includes a first rotation mechanism and a second rotation mechanism. The first rotation mechanism is connected to the end control assembly, and the second rotation mechanism is connected to the first rotation mechanism. The end control assembly drives the first rotation mechanism to rotate around a rotation axis of the first rotation mechanism, and the end control assembly also drives the first rotation mechanism and the second rotation mechanism to rotate around a rotation axis of the second rotation mechanism.

Abstract: A catheter system (100) for treating a treatment site (106) includes a first light source (124), a plurality of light guides (122A), a multiplexer (128), a multiplexer alignment system (142), and a first beamsplitter (268). The first light source (124) generates a source beam (124A). The multiplexer (128) receives the source beam (124A), and alternatively directs the source beam (124A) to each of the plurality of light guides (122A). The multiplexer alignment system (142) is operatively coupled to the multiplexer (128). The multiplexer alignment system (142) includes a second light source (270) that generates a probe source beam (270A) that is directed to scan across a guide proximal end (122P) of each of the plurality of light guides (122A) so that a time is determined to generate the source beam (124A) so that the source beam (124A) is optically coupled to the guide proximal end (122P) of each of the plurality of light guides (122A).

Abstract: Methods and systems for recording evoked potentials evoked during electrical stimulation of a patient's neural tissue are disclosed. The methods and systems are useful with treatment modalities, such as spinal cord stimulation (SCS). The disclosed methods and system allow for stimulation artifacts to be reduced in, or removed from, the recorded signals. A residual portion of the stimulation artifact can be modeled and subtracted from a recorded signal that includes both artifact and neural response contributions.

Abstract: In certain embodiments, an ophthalmic laser surgical system for treating a floater in a vitreous of an eye includes a floater detection system, a laser device, and a computer. The floater detection system determines the location of the floater in the vitreous of the eye. The laser device directs a laser beam along a laser beam path towards the floater. The computer accesses a three-dimensional scan pattern for the laser beam that yields a three-dimensional pulse pattern of laser pulses. The three-dimensional pulse pattern has a bubble shield pulse pattern at the posterior side of the three-dimensional pulse pattern. The bubble shield pulse pattern forms a bubble shield that reduces laser radiation exposure at a retina of the eye. The computer instructs the laser device to direct the laser beam towards the floater according to the three-dimensional scan pattern.

Abstract: A microrobot including a propulsion system with a propulsion structure deformable in elongation/contraction along a main axis, an actuator or actuation zone configured to actuate sequentially elongation/contraction cycles of the propulsion structure, a light source aimed at, when activated, emitting at least one predetermined light signal, and a remote control unit. The light source includes an optical fiber, and is configured to be activated by the remote control unit, and the actuator or actuation zone is configured to be activated by the light signal emitted from the light source.