Abstract: A device and method for endovascular radiation therapy that prevents unwanted damage to blood vessels during treatment is described. The device is adapted to prevent the emission end of an energy delivery device from coming into contact with the wall of a blood vessel. The device is also adapted to sense the inputted radiation power and prevent irradiation above a preselected power or energy level. Both features serve to prevent radiation, having an overly high intensity or power density, from impacting the vessel wall and causing a puncture.

Abstract: A medical instrument handle includes a stem, a joystick assembly, and a medical-instrument-member first articulation cable. The stem has a proximal stem portion and a distal stem portion. The joystick assembly includes a platform, a proximal joystick portion and a distal joystick portion, wherein the distal joystick portion is articulatably connected to the proximal stem portion. The first articulation cable includes a proximal cable portion which is connected to the platform and which is substantially transversely constrained by the stem. Articulation of the joystick assembly with respect to the stem changes a distance between the platform and the stem as measured along the first articulation cable. A medical instrument includes a medical instrument handle and a medical end effector. Examples of medical end effectors include, without limitation, a medical grasper and a medical snare.

Abstract: The invention provides a cardiac rhythm management system for stimulating a heart having photosensitive tissue, vectors useful to photosensitize cells expressing the vectors, and methods for light induced depolarization of cells.

Abstract: A catheter structure is provided for use with an electroviscerogram (EVG) system. The catheter structure includes an elongated tube structure having distal and proximal ends. Three electrodes are associated with distal end of the tube structure and are constructed and arranged obtain signals relating to myoelectrical activity internally of an intra-abdominal organ to thereby locate targeted tissue that includes main pathways of electrical generation in the organ. Therapy delivery structure, associated with the distal end of the tube structure and separate from the electrodes, is constructed and arranged to provide therapy at the targeted tissue simultaneously as the electrodes obtain the signals at the targeted tissue so that effectiveness of the therapy can be monitored.

Abstract: A steerable laser probe may include a handle, an actuation mechanism of the handle, an optic fiber, and a housing tube. The housing tube may include a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness. The optic fiber may be disposed within the housing tube and within an inner bore of the handle. A portion of the optic fiber may be fixed to an inner portion of the housing tube.

Abstract: A steerable laser probe may include a handle, an actuation structure of the handle, a housing tube, a flexible tube, an optic fiber, and a wire having a pre-formed curve. The flexible tube may be disposed within the housing tube wherein a distal end of the flexible tube projects out from a distal end of the housing tube. The optic fiber may be disposed within an inner bore of the handle, the housing tube, and the flexible tube. The wire may be disposed within the housing tube.

Abstract: The invention relates to the combination of a light ray with a cytochrome C oxidase substrate for improving the appearance of the skin and/or the hair.

Abstract: A steerable laser probe may include a handle, and inner bore of the handle, an actuation lever of the handle, a housing tube, and an optic fiber disposed within the inner bore of the handle and the housing tube. The housing tube may have a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness.

Abstract: Optical energy-based methods and apparatus for sealing vascular tissue involves deforming vascular tissue to bring different layers of the vascular tissue into contact each other and illuminating the vascular tissue with a light beam having at least one portion of its spectrum overlapping with the absorption spectrum of the vascular tissue. The apparatus may include two deforming members configured to deform the vascular tissue placed between the deforming members. The apparatus may also include an optical system that has a light source configured to generate light, a light distribution element configured to distribute the light across the vascular tissue, and a light guide configured to guide the light from the light source to the light distribution element. The apparatus may further include a cutting member configured to cut the vascular tissue and to illuminate the vascular tissue with light to seal at least one cut surface of the vascular tissue.

Abstract: A steerable laser probe may include a handle, an actuation lever, an optic fiber, and a housing tube. The housing tube may have a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness. The optic fiber may be disposed within the housing tube and within an inner bore of the handle. An actuation of the actuation lever about a pivot pin of the handle may gradually curve the optic fiber. An actuation of the actuation lever about the pivot pin of the handle may gradually straighten the optic fiber.

Abstract: A rooter includes a rotatable element, an actuator for causing the rotatable element to rotate, and a coupling feature for rotatably coupling an elongated medical instrument to the rotatable element. The rotatable element may be at least partially contained within the interior of a housing or another element that remains substantially stationary as the actuator causes the rotatable element to rotate. The rooter may be used with a variety of elongated medical instruments, such as needles, drill bits, trocars, wires, catheters, tubes, and other elongated instruments that are used to enable or effect medical procedures within the body of a subject. The rooter may be used for a variety of purposes, including, without limitation, the introduction of an elongated medical instrument into the body of a subject or its removal from the subject's body; removing, breaking up, or eliminating obstructions (e.g., blood clots, plaques, etc.) from the body of a subject; and obtaining samples from a subject's body.

Abstract: Surgical instrument with a handpiece having a drive and with a surgical tool, which has a tube and a working part with a shaft and with a tool head, the tube of the surgical tool can be detachably connected to the handpiece by a first coupling part and the shaft of the working part can be detachably connected to a drive shaft in the form of a pin of the drive by a second coupling part simultaneously.

Abstract: A device for controlled translational displacement of an elongated element that terminates in a frontal functional end, in particular an instrument/tool that is designed to be brought to an internal site in a patient, more particularly an exploratory instrument/surgical tool placed in a catheter or in an operating channel or working channel of a flexible endoscope, whereby the device includes a linear actuator that acts at the rear end of the elongated element that is located opposite its frontal functional end. The device that is characterized in that the actuator includes of a direct-drive electromagnetic linear motor with a shaft that moves in translation relative to a stator and that drives the elongated element, whereby the shaft can also be coupled to a rotary motor.

Abstract: The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue.

Abstract: A medical coil is provided which is formed by winding an element wire, and includes a convex part provided on a first end of a width direction of the element wire, and a concave part provided on a second end of the width direction of the element wire. At least one of the convex part and the concave part has a slant face. When a compressive force is applied in an axial direction of the medical coil, the convex part and the concave part adjacent to each other are configured to approach each other. A segment which connects a top part of the convex part which protrudes the most and a deepest part of the concave part which is deepest forms an angle so as not to be parallel to an axis of the medical coil.

Abstract: A system and method for automatically adjusting medical displays is arranged to communicate medical information to a caregiver. The system includes at least one display for displaying medical information, a wireless communication device associated with the display and a wireless communication device associated with the caregiver. The wireless communication device associated with the display is arranged to realize if the wireless communication device associated with the caregiver, and thus the caregiver, is present in a predetermined area near the display. A controller associated with the display is arranged to automatically adjust at least one characteristic of the display based upon the realized presence of the caregiver. According to the method, the presence of the caregiver is detected when the caregiver enters the predetermined area near the display. At lease one characteristic of the display is thus adjusted automatically based upon the detected presence of the caregiver in the predetermined area.

Abstract: A treatment device for the surgical correction of hyperopia in the eye comprising a laser device controlled by a control device. The laser device separating corneal tissue by applying laser radiation. The control device controls the laser device for emitting the laser radiation into the cornea such that a lenticule-shaped volume is isolated. Removal thereof effects the desired correction. The control device (12) predefines the volume such that a posterior surface and an anterior surface are connected via an edge surface that has a width in projection along the visual axis that is wider than the one which a straight line in the same projection, that is perpendicular at the edge of the posterior or the anterior surface would have relative to the associated surface and connects the anterior surface to the posterior surface or to the perceived extension thereof.

Abstract: A treatment apparatus for operatively correcting myopia or hyperopia in an eye includes a laser device controlled by a control device and that separates the corneal tissue by applying a laser beam. The control device controls the laser device to emit the laser beam into the cornea such that a lenticule-shaped volume is isolated in the cornea. The control device, when controlling the laser device, predefines the lenticule-shaped volume such that the volume has a minimum thickness of between 5 and 50 ?m. For myopia correction, the minimum thickness occurs on the edge of the volume, and for hyperopia correction the minimum thickness occurs in the region of the visual axis.

Abstract: Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one such device, target cells are stimulated using an implantable device. The device includes a light source for producing light from electrical power. An optical transmission element is made from a material that is substantially transparent to the light from the light source. This transmission element substantially encases the light source at a proximal end. The transmission element delivers light from the light source to a distal end. The shape and size of the transmission element facilitates implanting of the element within a patient. A fixation portion physically couples to the optical transmission element and secures the device to the patient. A heat dissipation portion removes heat from the near optical transmission element and the light source and dissipates the removed heat through the fixation portion.

Abstract: An ophthalmic laser treatment apparatus includes a light interference optical unit, an irradiation unit, a luminance transition information detecting unit, a focused state detecting unit, and a guide unit. The light interference optical unit is configured to acquire a depth profile of a patient's eye tissue. The luminance transition information detecting unit is configured to control a first focus position adjusting unit to shift a focus position of a measurement light to acquire a depth profile in each focus position. The focused state detecting unit is configured to detect a focused state in the patient's eye tissue based on luminance transition information acquired by the luminance transition information detecting unit. The guide unit is configured to guide a focus position of a laser beam to be adjusted based on a result of detection of the focused state detecting unit.