Patents Examined by M. E. Ceperley
  • Patent number: 4596997
    Abstract: A phenolic compound represented by the formula: ##STR1## a process for producing it and a recording material comprising a support bearing a heat- or pressure-sensitive color-forming layer containing the phenolic compound and a leuco dye.
    Type: Grant
    Filed: January 31, 1985
    Date of Patent: June 24, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventor: Masaki Shinmoto
  • Patent number: 4595766
    Abstract: The invention relates to a novel process for the preparation of the optically pure 2S- or 2R-indolinecarboxylic acid of the formula ##STR1## and salts thereof. The process comprises forming the heterocyclic 5-membered ring in formula I from an open chain precursor by diastereoselective cyclization.
    Type: Grant
    Filed: October 26, 1984
    Date of Patent: June 17, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Achim Roloff, Heinz W. Gschwend
  • Patent number: 4585879
    Abstract: Disclosed herein is a process for obtaining indoline-2-carboxylic acid (or derivatives thereof) comprising the following steps: (a) reducing .alpha.-oxo-2-nitrobenzenepropanoic acid to .alpha.-hydroxy-2-nitrobenzenepropanoic acid, (b) replacing the hydroxyl group of the latter with a chlorine atom utilizing a selected Vilsmeier chlorinating reagent at temperatures of at least 20.degree. C., (c) reducing the nitro group of the resulting .alpha.-chloro-2-nitrobenzenepropanoic acid to obtain .alpha.-chloro-2-aminobenzenepropanoic acid, and (d) cyclizing the latter in aqueous base to form the desired indoline-2-carboxylic acid. Alternately, steps (c) and (d) may be combined in a one pot step by using, for example, a Raney nickel-hydrazine reducing medium.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: April 29, 1986
    Assignee: American Home Products Corporation
    Inventors: Michael W. Winkley, Ronald J. McCaully